Project measure / variable:   Threadgill1   ALT_Rx100_4h

ID, description, units MPD:19407   ALT_Rx100_4h   alanine transaminase (serum ALT), t=4h   [IU/L]  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   7 strains     sex: m     age: 8-17wks
Procedure metabolic panel
Ontology mappings

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  STRAIN COMPARISON PLOT


  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means51.6   IU/L
Median of the strain means50.2   IU/L
SD of the strain means± 10.4
Coefficient of variation (CV)0.202
Min–max range of strain means36.3   –   63.8   IU/L
Mean sample size per strain3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 2317.3333 386.2222 0.3961 0.8719
Residuals 18 17550.6667 975.037


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
B6C3F1/J m 60.2 41.7   4 20.9 0.692 24.0, 119.0 0.82
C3H/HeJ m 61.2 14.9   4 7.47 0.244 45.0, 80.0 0.92
C57BL/10J m 63.8 11.1   4 5.54 0.174 50.0, 75.0 1.17
CBA/J m 47.0 25.5   2   18.0 0.542 29.0, 65.0 -0.44
DBA/2J m 50.2 45.9   4 22.9 0.913 24.0, 119.0 -0.13
LP/J m 36.3 15.3   3 8.82 0.42 23.0, 53.0 -1.46
NOD/ShiLtJ m 42.5 35.9   4 17.9 0.844 7.0, 88.0 -0.87


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6C3F1/J m 60.25 15.6128 93.0513 27.4487
C3H/HeJ m 61.25 15.6128 94.0513 28.4487
C57BL/10J m 63.75 15.6128 96.5513 30.9487
CBA/J m 47.0 22.0798 93.388 0.612
DBA/2J m 50.25 15.6128 83.0513 17.4487
LP/J m 36.3333 18.0281 74.209 0.0
NOD/ShiLtJ m 42.5 15.6128 75.3013 9.6987




  GWAS USING LINEAR MIXED MODELS

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