Phenotype measure

ID, description, units MPD:41808   ALP   alkaline phosphatase (serum ALP)   [IU/L]
Data set, strains Donahue9   B6.PWD consomic w/par   25 strains     sex: both     age: 11wks
Procedure metabolic panel
Ontology mappings


  STRAIN COMPARISON PLOT
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Donahue9 - alkaline phosphatase (serum ALP)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains25 strains
Mean of the strain means108   IU/L 87.7   IU/L
Median of the strain means98.2   IU/L 75.2   IU/L
SD of the strain means± 33.3 ± 38.1
Coefficient of variation (CV)0.310 0.435
Min–max range of strain means60.6   –   190   IU/L 54.7   –   240   IU/L
Mean sample size per strain8.3   mice 8.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 31336.3306 31336.3306 74.2198 < 0.0001
strain 22 414569.4757 18844.0671 44.632 < 0.0001
sex:strain 22 83145.7583 3779.3526 8.9514 < 0.0001
Residuals 334 141018.0433 422.2097


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 129.0 24.0   8 8.48 0.186 102.0, 180.0 0.64
B6.PWD-Chr1 m 103.0 14.9   8 5.27 0.144 92.0, 139.0 0.4
B6.PWD-Chr10.1 f 74.6 24.2   8 8.55 0.324 37.0, 106.0 -0.99
B6.PWD-Chr10.1 m 73.1 7.06   8 2.5 0.0965 63.0, 84.0 -0.38
B6.PWD-Chr10.2 f 101.0 14.7   11 4.42 0.145 84.0, 125.0 -0.2
B6.PWD-Chr10.2 m 80.5 21.0   10 6.64 0.261 55.0, 113.0 -0.19
B6.PWD-Chr10.3 f 101.0 18.5   8 6.53 0.182 73.0, 127.0 -0.2
B6.PWD-Chr10.3 m 75.8 5.5   8 1.94 0.0726 66.0, 85.0 -0.31
B6.PWD-Chr11.1 f 86.8 14.9   12 4.31 0.172 70.0, 121.0 -0.62
B6.PWD-Chr11.1 m 72.8 12.8   12 3.68 0.175 53.0, 101.0 -0.39
B6.PWD-Chr11.2 f 60.6 11.3   10 3.57 0.186 45.0, 81.0 -1.41
B6.PWD-Chr11.2 m 54.7 7.99   10 2.53 0.146 39.0, 61.0 -0.87
B6.PWD-Chr11.3 f 83.5 20.0   10 6.34 0.24 52.0, 123.0 -0.72
B6.PWD-Chr11.3 m 69.0 20.5   8 7.24 0.297 53.0, 118.0 -0.49
B6.PWD-Chr12 f 78.8 14.6   8 5.15 0.185 60.0, 96.0 -0.86
B6.PWD-Chr12 m 61.1 13.4   8 4.73 0.219 47.0, 91.0 -0.7
B6.PWD-Chr14 f 83.3 15.6   9 5.2 0.187 54.0, 106.0 -0.73
B6.PWD-Chr14 m 60.1 5.95   9 1.98 0.0989 49.0, 68.0 -0.72
B6.PWD-Chr15 f 120.0 21.2   8 7.48 0.176 88.0, 146.0 0.37
B6.PWD-Chr15 m 87.8 17.0   8 6.02 0.194 61.0, 107.0 0.0
B6.PWD-Chr16 f 77.5 15.1   10 4.78 0.195 66.0, 117.0 -0.9
B6.PWD-Chr16 m 61.7 24.5   6 9.99 0.397 41.0, 104.0 -0.68
B6.PWD-Chr17 f 118.0 10.7   8 3.77 0.0906 103.0, 130.0 0.31
B6.PWD-Chr17 m 63.0 16.5   8 5.84 0.262 47.0, 98.0 -0.65
B6.PWD-Chr18 f 115.0 9.5   8 3.36 0.0824 101.0, 131.0 0.22
B6.PWD-Chr18 m 101.0 8.62   8 3.05 0.085 93.0, 119.0 0.35
B6.PWD-Chr19 f 86.4 6.09   8 2.15 0.0705 78.0, 95.0 -0.63
B6.PWD-Chr19 m 75.2 6.41   8 2.27 0.0852 60.0, 80.0 -0.33
B6.PWD-Chr3 m 113.0 19.7   9 6.57 0.174 86.0, 139.0 0.66
B6.PWD-Chr5 f 108.0 10.9   8 3.85 0.101 91.0, 124.0 0.01
B6.PWD-Chr5 m 95.5 9.13   8 3.23 0.0956 77.0, 106.0 0.2
B6.PWD-Chr6 f 133.0 27.8   8 9.82 0.209 82.0, 155.0 0.76
B6.PWD-Chr6 m 123.0 16.6   8 5.86 0.135 105.0, 154.0 0.93
B6.PWD-Chr9 f 98.2 19.6   4 9.78 0.199 80.0, 126.0 -0.28
B6.PWD-Chr9 m 84.4 23.7   7 8.97 0.281 62.0, 131.0 -0.09
B6.PWD-ChrX.1 f 95.2 24.4   5 10.9 0.256 68.0, 133.0 -0.37
B6.PWD-ChrX.1 m 71.8 28.8   6 11.8 0.401 37.0, 109.0 -0.42
B6.PWD-ChrX.2 m 64.2 10.5   9 3.51 0.164 51.0, 88.0 -0.62
B6.PWD-ChrX.3 f 190.0 88.1   8 31.2 0.464 93.0, 293.0 2.47
B6.PWD-ChrX.3 m 68.4 10.2   8 3.61 0.149 57.0, 83.0 -0.51
B6.PWD-ChrY f 96.8 30.9   8 10.9 0.319 64.0, 135.0 -0.32
B6.PWD-ChrY m 85.2 11.6   8 4.09 0.136 67.0, 109.0 -0.07
B6.PWD-mt f 90.9 11.1   8 3.92 0.122 77.0, 112.0 -0.5
B6.PWD-mt m 68.1 10.2   8 3.6 0.149 53.0, 80.0 -0.51
C57BL/6J f 171.0 11.7   8 4.13 0.0681 159.0, 194.0 1.9
C57BL/6J m 140.0 16.4   8 5.79 0.117 119.0, 162.0 1.37
PWD/PhJ f 174.0 16.2   8 5.72 0.0932 154.0, 199.0 1.99
PWD/PhJ m 240.0 13.2   9 4.38 0.0549 222.0, 263.0 4.0


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 128.875 7.2647 143.1654 114.5846
B6.PWD-Chr1 m 103.25 7.2647 117.5404 88.9596
B6.PWD-Chr10.1 f 74.625 7.2647 88.9154 60.3346
B6.PWD-Chr10.1 m 73.125 7.2647 87.4154 58.8346
B6.PWD-Chr10.2 f 101.2727 6.1954 113.4596 89.0859
B6.PWD-Chr10.2 m 80.5 6.4978 93.2817 67.7183
B6.PWD-Chr10.3 f 101.375 7.2647 115.6654 87.0846
B6.PWD-Chr10.3 m 75.75 7.2647 90.0404 61.4596
B6.PWD-Chr11.1 f 86.75 5.9316 98.418 75.082
B6.PWD-Chr11.1 m 72.8333 5.9316 84.5014 61.1653
B6.PWD-Chr11.2 f 60.6 6.4978 73.3817 47.8183
B6.PWD-Chr11.2 m 54.7 6.4978 67.4817 41.9183
B6.PWD-Chr11.3 f 83.5 6.4978 96.2817 70.7183
B6.PWD-Chr11.3 m 69.0 7.2647 83.2904 54.7096
B6.PWD-Chr12 f 78.75 7.2647 93.0404 64.4596
B6.PWD-Chr12 m 61.125 7.2647 75.4154 46.8346
B6.PWD-Chr14 f 83.3333 6.8492 96.8064 69.8602
B6.PWD-Chr14 m 60.1111 6.8492 73.5842 46.638
B6.PWD-Chr15 f 119.875 7.2647 134.1654 105.5846
B6.PWD-Chr15 m 87.75 7.2647 102.0404 73.4596
B6.PWD-Chr16 f 77.5 6.4978 90.2817 64.7183
B6.PWD-Chr16 m 61.6667 8.3886 78.1678 45.1656
B6.PWD-Chr17 f 117.5 7.2647 131.7904 103.2096
B6.PWD-Chr17 m 63.0 7.2647 77.2904 48.7096
B6.PWD-Chr18 f 115.25 7.2647 129.5404 100.9596
B6.PWD-Chr18 m 101.375 7.2647 115.6654 87.0846
B6.PWD-Chr19 f 86.375 7.2647 100.6654 72.0846
B6.PWD-Chr19 m 75.25 7.2647 89.5404 60.9596
B6.PWD-Chr5 f 107.75 7.2647 122.0404 93.4596
B6.PWD-Chr5 m 95.5 7.2647 109.7904 81.2096
B6.PWD-Chr6 f 133.125 7.2647 147.4154 118.8346
B6.PWD-Chr6 m 122.875 7.2647 137.1654 108.5846
B6.PWD-Chr9 f 98.25 10.2739 118.4596 78.0404
B6.PWD-Chr9 m 84.4286 7.7663 99.7056 69.1515
B6.PWD-ChrX.1 f 95.2 9.1892 113.2761 77.1239
B6.PWD-ChrX.1 m 71.8333 8.3886 88.3344 55.3322
B6.PWD-ChrX.3 f 190.0 7.2647 204.2904 175.7096
B6.PWD-ChrX.3 m 68.375 7.2647 82.6654 54.0846
B6.PWD-ChrY f 96.75 7.2647 111.0404 82.4596
B6.PWD-ChrY m 85.25 7.2647 99.5404 70.9596
B6.PWD-mt f 90.875 7.2647 105.1654 76.5846
B6.PWD-mt m 68.125 7.2647 82.4154 53.8346
C57BL/6J f 171.375 7.2647 185.6654 157.0846
C57BL/6J m 140.0 7.2647 154.2904 125.7096
PWD/PhJ f 173.625 7.2647 187.9154 159.3346
PWD/PhJ m 239.6667 6.8492 253.1398 226.1936


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 116.0625 5.1369 126.1673 105.9577
B6.PWD-Chr10.1 both 73.875 5.1369 83.9798 63.7702
B6.PWD-Chr10.2 both 90.8864 4.489 99.7166 82.0561
B6.PWD-Chr10.3 both 88.5625 5.1369 98.6673 78.4577
B6.PWD-Chr11.1 both 79.7917 4.1943 88.0422 71.5411
B6.PWD-Chr11.2 both 57.65 4.5946 66.688 48.612
B6.PWD-Chr11.3 both 76.25 4.8733 85.8363 66.6637
B6.PWD-Chr12 both 69.9375 5.1369 80.0423 59.8327
B6.PWD-Chr14 both 71.7222 4.8431 81.2491 62.1953
B6.PWD-Chr15 both 103.8125 5.1369 113.9173 93.7077
B6.PWD-Chr16 both 69.5833 5.3054 80.0196 59.1471
B6.PWD-Chr17 both 90.25 5.1369 100.3548 80.1452
B6.PWD-Chr18 both 108.3125 5.1369 118.4173 98.2077
B6.PWD-Chr19 both 80.8125 5.1369 90.9173 70.7077
B6.PWD-Chr5 both 101.625 5.1369 111.7298 91.5202
B6.PWD-Chr6 both 128.0 5.1369 138.1048 117.8952
B6.PWD-Chr9 both 91.3393 6.4395 104.0064 78.6722
B6.PWD-ChrX.1 both 83.5167 6.2211 95.7542 71.2791
B6.PWD-ChrX.3 both 129.1875 5.1369 139.2923 119.0827
B6.PWD-ChrY both 91.0 5.1369 101.1048 80.8952
B6.PWD-mt both 79.5 5.1369 89.6048 69.3952
C57BL/6J both 155.6875 5.1369 165.7923 145.5827
PWD/PhJ both 206.6458 4.9922 216.466 196.8257