MPD: Project measures / variables set: Rusyn2 BUN

Project measures / variables set: Rusyn2 BUN_ctrl

ID, description, units	MPD:36132 BUN_ctrl blood urea nitrogen (serum BUN), control group [mg/dL] trichloroethylene study
Measures	• time: 2h • 8h • 24h
Data set, strains	Rusyn2 inbred 16 strains sex: m age: 7wks
Procedure	metabolic panel
Comparison	timecourse but different cohorts
Ontology mappings	VT:0010487 response to xenobiotic stimulus trait VT:0005265 blood urea nitrogen amount MA:0002502 serum MP:0005265 abnormal blood urea nitrogen level MP:0008872 abnormal physiological response to xenobiotic

Values Means Δ Means Z-scores

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Rusyn2 - blood urea nitrogen (serum BUN), control group

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
time	2	46.7008	23.3504	1.3398	0.2672
strain	14	614.4335	43.8881	2.5182	0.0046
time:strain	28	1044.4322	37.3011	2.1403	0.0038
Residuals	88	1533.6667	17.428

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Rusyn2	36132	metabolic panel	trichloroethylene	blood urea nitrogen (serum BUN), control group [mg/dL] 2h after baseline BUN_2_ctrl	inbred	15	m	7wks
Rusyn2	36133	metabolic panel	trichloroethylene	blood urea nitrogen (serum BUN), control group [mg/dL] 8h after baseline BUN_8_ctrl	inbred	16	m	7wks
Rusyn2	36134	metabolic panel	trichloroethylene	blood urea nitrogen (serum BUN), control group [mg/dL] 24h after baseline BUN_24_ctrl	inbred	15	m	7wks