Project measure / variable:   Threadgill1   ALT_Rx100_24h

ID, description, units MPD:19409   ALT_Rx100_24h   alanine transaminase (serum ALT), t=24h   [IU/L]  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   7 strains     sex: m     age: 8-17wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Threadgill1 - alanine transaminase (serum ALT), t=24h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means54.2   IU/L
Median of the strain means47.8   IU/L
SD of the strain means± 18.0
Coefficient of variation (CV)0.332
Min–max range of strain means40.2   –   93.0   IU/L
Mean sample size per strain3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 6086.1667 1014.3611 3.3062 0.0242
Residuals 17 5215.6667 306.8039


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6C3F1/J m 45.2 18.6   4 9.31 0.412 29.0, 70.0 -0.5
C3H/HeJ m 47.8 11.8   4 5.92 0.248 38.0, 64.0 -0.36
C57BL/10J m 49.7 7.64   3 4.41 0.154 43.0, 58.0 -0.25
CBA/J m 45.0 5.66   2   4.0 0.126 41.0, 49.0 -0.51
DBA/2J m 58.8 21.8   4 10.9 0.371 29.0, 77.0 0.25
LP/J m 93.0 32.4   3 18.7 0.349 57.0, 120.0 2.15
NOD/ShiLtJ m 40.2 4.86   4 2.43 0.121 33.0, 43.0 -0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6C3F1/J m 45.25 8.7579 63.7276 26.7724
C3H/HeJ m 47.75 8.7579 66.2276 29.2724
C57BL/10J m 49.6667 10.1128 71.0027 28.3306
CBA/J m 45.0 12.3856 71.1312 18.8688
DBA/2J m 58.75 8.7579 77.2276 40.2724
LP/J m 93.0 10.1128 114.3361 71.6639
NOD/ShiLtJ m 40.25 8.7579 58.7276 21.7724




  GWAS USING LINEAR MIXED MODELS