MPD: Project measures / variables set: Rusyn5 ALT

Project measures / variables set: Rusyn5 ALT

ID, description, units	MPD:43001 ALT serum alanine transaminase (ALT) [IU/L] high-fat diet and ethanol study
Measures	• high-fat only • high-fat and ethanol
Data set, strains	Rusyn5 inbred 14 strains sex: m age: 8-14wks
Procedure	metabolic panel
Comparison	control group vs. treated group
Ontology mappings	VT:0001573 blood alanine transaminase amount VT:0010489 response to alcohol trait MA:0002502 serum MP:0001573 abnormal circulating alanine transaminase level

Values Means Δ Means Z-scores

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Rusyn5 - serum alanine transaminase (ALT)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	42749.8464	42749.8464	73.3855	< 0.0001
group:strain	13	52656.3452	4050.4881	6.9532	< 0.0001
Residuals	56	32622.1284	582.538
strain	13	65365.9799	5028.1523	8.6315	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Rusyn5	43001	metabolic panel	high-fat diet and ethanol	serum alanine transaminase (ALT) [IU/L] high-fat only ALT_hf	inbred	14	m	8-14wks
Rusyn5	43002	metabolic panel	high-fat diet and ethanol	serum alanine transaminase (ALT) [IU/L] high-fat and ethanol ALT_hfe	inbred	14	m	8-14wks