Project measure / variable:   Donahue9   TP

ID, description, units MPD:41816   TP   total protein (serum TP)   [g/dL]  
Data set, strains Donahue9   B6.PWD consomic w/par   25 strains     sex: both     age: 11wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue9 - total protein (serum TP)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains25 strains
Mean of the strain means5.75   g/dL 5.91   g/dL
Median of the strain means5.62   g/dL 5.80   g/dL
SD of the strain means± 0.559 ± 0.511
Coefficient of variation (CV)0.0972 0.0865
Min–max range of strain means4.99   –   7.18   g/dL 5.21   –   7.07   g/dL
Mean sample size per strain8.3   mice 8.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.1418 3.1418 20.2978 < 0.0001
strain 22 84.726 3.8512 24.8809 < 0.0001
sex:strain 22 13.0263 0.5921 3.8253 < 0.0001
Residuals 334 51.6981 0.1548


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 5.8 0.65   8 0.23 0.112 4.8, 6.9 0.09
B6.PWD-Chr1 m 5.8 0.628   8 0.222 0.108 4.7, 6.5 -0.22
B6.PWD-Chr10.1 f 5.21 0.517   8 0.183 0.0991 4.6, 6.2 -0.97
B6.PWD-Chr10.1 m 5.36 0.498   8 0.176 0.0929 4.5, 5.9 -1.08
B6.PWD-Chr10.2 f 5.62 0.209   11 0.063 0.0372 5.2, 6.0 -0.23
B6.PWD-Chr10.2 m 5.8 0.294   10 0.0931 0.0508 5.3, 6.1 -0.22
B6.PWD-Chr10.3 f 5.62 0.301   8 0.106 0.0535 5.1, 6.0 -0.23
B6.PWD-Chr10.3 m 5.9 0.227   8 0.0802 0.0384 5.5, 6.2 -0.03
B6.PWD-Chr11.1 f 5.98 0.335   12 0.0968 0.056 5.5, 6.5 0.41
B6.PWD-Chr11.1 m 6.24 0.291   12 0.0839 0.0466 5.7, 6.7 0.64
B6.PWD-Chr11.2 f 5.63 0.411   10 0.13 0.073 5.0, 6.5 -0.22
B6.PWD-Chr11.2 m 5.83 0.313   10 0.0989 0.0537 5.5, 6.5 -0.16
B6.PWD-Chr11.3 f 5.92 0.266   10 0.0841 0.0449 5.6, 6.3 0.3
B6.PWD-Chr11.3 m 5.75 0.33   8 0.116 0.0573 5.4, 6.2 -0.32
B6.PWD-Chr12 f 7.18 0.623   8 0.22 0.0868 6.4, 8.2 2.56
B6.PWD-Chr12 m 7.07 0.575   8 0.203 0.0813 6.2, 7.8 2.26
B6.PWD-Chr14 f 5.68 0.205   9 0.0683 0.0361 5.5, 6.1 -0.13
B6.PWD-Chr14 m 5.91 0.382   9 0.127 0.0647 5.3, 6.4 -0.01
B6.PWD-Chr15 f 5.31 0.304   8 0.108 0.0573 4.9, 5.8 -0.79
B6.PWD-Chr15 m 5.22 0.399   8 0.141 0.0764 4.6, 5.7 -1.36
B6.PWD-Chr16 f 5.25 0.268   10 0.0847 0.051 4.8, 5.6 -0.9
B6.PWD-Chr16 m 6.27 0.344   6 0.141 0.055 5.7, 6.6 0.7
B6.PWD-Chr17 f 5.55 0.262   8 0.0926 0.0472 5.1, 5.9 -0.36
B6.PWD-Chr17 m 5.51 0.3   8 0.106 0.0544 5.1, 5.9 -0.79
B6.PWD-Chr18 f 4.99 0.23   8 0.0811 0.046 4.7, 5.4 -1.36
B6.PWD-Chr18 m 5.42 0.219   8 0.0773 0.0403 5.1, 5.8 -0.97
B6.PWD-Chr19 f 5.25 0.302   8 0.107 0.0576 4.6, 5.6 -0.9
B6.PWD-Chr19 m 5.49 0.36   8 0.127 0.0657 4.9, 6.0 -0.83
B6.PWD-Chr3 m 5.21 0.639   9 0.213 0.123 4.0, 6.2 -1.38
B6.PWD-Chr5 f 5.36 0.366   8 0.129 0.0683 4.8, 5.9 -0.7
B6.PWD-Chr5 m 5.62 0.471   8 0.167 0.0838 4.8, 6.1 -0.57
B6.PWD-Chr6 f 5.51 0.34   8 0.12 0.0617 5.1, 6.1 -0.43
B6.PWD-Chr6 m 6.51 0.196   8 0.0693 0.0301 6.2, 6.7 1.17
B6.PWD-Chr9 f 5.85 0.723   4 0.362 0.124 5.2, 6.7 0.18
B6.PWD-Chr9 m 5.8 0.523   7 0.198 0.0901 5.0, 6.4 -0.22
B6.PWD-ChrX.1 f 6.48 0.722   5 0.323 0.111 5.7, 7.5 1.3
B6.PWD-ChrX.1 m 5.93 0.68   6 0.278 0.115 5.2, 6.9 0.03
B6.PWD-ChrX.2 m 6.52 0.299   9 0.0997 0.0459 6.0, 6.9 1.18
B6.PWD-ChrX.3 f 6.29 0.253   8 0.0895 0.0403 6.0, 6.6 0.96
B6.PWD-ChrX.3 m 6.48 0.255   8 0.0901 0.0394 6.1, 6.8 1.11
B6.PWD-ChrY f 6.41 0.69   8 0.244 0.108 5.7, 7.4 1.18
B6.PWD-ChrY m 5.69 0.422   8 0.149 0.0743 4.9, 6.2 -0.44
B6.PWD-mt f 6.81 0.455   8 0.161 0.0668 6.3, 7.4 1.89
B6.PWD-mt m 7.03 0.568   8 0.201 0.0808 6.1, 7.5 2.18
C57BL/6J f 5.45 0.177   8 0.0627 0.0325 5.2, 5.8 -0.54
C57BL/6J m 6.12 0.167   8 0.059 0.0272 5.8, 6.3 0.4
PWD/PhJ f 5.12 0.175   8 0.062 0.0342 4.8, 5.4 -1.13
PWD/PhJ m 5.37 0.194   9 0.0645 0.0361 5.1, 5.7 -1.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 5.8 0.1391 6.0736 5.5264
B6.PWD-Chr1 m 5.8 0.1391 6.0736 5.5264
B6.PWD-Chr10.1 f 5.2125 0.1391 5.4861 4.9389
B6.PWD-Chr10.1 m 5.3625 0.1391 5.6361 5.0889
B6.PWD-Chr10.2 f 5.6182 0.1186 5.8515 5.3848
B6.PWD-Chr10.2 m 5.8 0.1244 6.0447 5.5553
B6.PWD-Chr10.3 f 5.625 0.1391 5.8986 5.3514
B6.PWD-Chr10.3 m 5.9 0.1391 6.1736 5.6264
B6.PWD-Chr11.1 f 5.9833 0.1136 6.2067 5.7599
B6.PWD-Chr11.1 m 6.2417 0.1136 6.4651 6.0183
B6.PWD-Chr11.2 f 5.63 0.1244 5.8747 5.3853
B6.PWD-Chr11.2 m 5.83 0.1244 6.0747 5.5853
B6.PWD-Chr11.3 f 5.92 0.1244 6.1647 5.6753
B6.PWD-Chr11.3 m 5.75 0.1391 6.0236 5.4764
B6.PWD-Chr12 f 7.175 0.1391 7.4486 6.9014
B6.PWD-Chr12 m 7.075 0.1391 7.3486 6.8014
B6.PWD-Chr14 f 5.6778 0.1311 5.9357 5.4198
B6.PWD-Chr14 m 5.9111 0.1311 6.1691 5.6531
B6.PWD-Chr15 f 5.3125 0.1391 5.5861 5.0389
B6.PWD-Chr15 m 5.225 0.1391 5.4986 4.9514
B6.PWD-Chr16 f 5.25 0.1244 5.4947 5.0053
B6.PWD-Chr16 m 6.2667 0.1606 6.5826 5.9507
B6.PWD-Chr17 f 5.55 0.1391 5.8236 5.2764
B6.PWD-Chr17 m 5.5125 0.1391 5.7861 5.2389
B6.PWD-Chr18 f 4.9875 0.1391 5.2611 4.7139
B6.PWD-Chr18 m 5.425 0.1391 5.6986 5.1514
B6.PWD-Chr19 f 5.25 0.1391 5.5236 4.9764
B6.PWD-Chr19 m 5.4875 0.1391 5.7611 5.2139
B6.PWD-Chr5 f 5.3625 0.1391 5.6361 5.0889
B6.PWD-Chr5 m 5.625 0.1391 5.8986 5.3514
B6.PWD-Chr6 f 5.5125 0.1391 5.7861 5.2389
B6.PWD-Chr6 m 6.5125 0.1391 6.7861 6.2389
B6.PWD-Chr9 f 5.85 0.1967 6.237 5.463
B6.PWD-Chr9 m 5.8 0.1487 6.0925 5.5075
B6.PWD-ChrX.1 f 6.48 0.1759 6.8261 6.1339
B6.PWD-ChrX.1 m 5.9333 0.1606 6.2493 5.6174
B6.PWD-ChrX.3 f 6.2875 0.1391 6.5611 6.0139
B6.PWD-ChrX.3 m 6.475 0.1391 6.7486 6.2014
B6.PWD-ChrY f 6.4125 0.1391 6.6861 6.1389
B6.PWD-ChrY m 5.6875 0.1391 5.9611 5.4139
B6.PWD-mt f 6.8125 0.1391 7.0861 6.5389
B6.PWD-mt m 7.025 0.1391 7.2986 6.7514
C57BL/6J f 5.45 0.1391 5.7236 5.1764
C57BL/6J m 6.125 0.1391 6.3986 5.8514
PWD/PhJ f 5.125 0.1391 5.3986 4.8514
PWD/PhJ m 5.3667 0.1311 5.6246 5.1087


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 5.8 0.0984 5.9935 5.6065
B6.PWD-Chr10.1 both 5.2875 0.0984 5.481 5.094
B6.PWD-Chr10.2 both 5.7091 0.086 5.8782 5.54
B6.PWD-Chr10.3 both 5.7625 0.0984 5.956 5.569
B6.PWD-Chr11.1 both 6.1125 0.0803 6.2705 5.9545
B6.PWD-Chr11.2 both 5.73 0.088 5.9031 5.5569
B6.PWD-Chr11.3 both 5.835 0.0933 6.0185 5.6515
B6.PWD-Chr12 both 7.125 0.0984 7.3185 6.9315
B6.PWD-Chr14 both 5.7944 0.0927 5.9769 5.612
B6.PWD-Chr15 both 5.2687 0.0984 5.4622 5.0753
B6.PWD-Chr16 both 5.7583 0.1016 5.9582 5.5585
B6.PWD-Chr17 both 5.5312 0.0984 5.7247 5.3378
B6.PWD-Chr18 both 5.2062 0.0984 5.3997 5.0128
B6.PWD-Chr19 both 5.3687 0.0984 5.5622 5.1753
B6.PWD-Chr5 both 5.4937 0.0984 5.6872 5.3003
B6.PWD-Chr6 both 6.0125 0.0984 6.206 5.819
B6.PWD-Chr9 both 5.825 0.1233 6.0675 5.5825
B6.PWD-ChrX.1 both 6.2067 0.1191 6.441 5.9724
B6.PWD-ChrX.3 both 6.3812 0.0984 6.5747 6.1878
B6.PWD-ChrY both 6.05 0.0984 6.2435 5.8565
B6.PWD-mt both 6.9187 0.0984 7.1122 6.7253
C57BL/6J both 5.7875 0.0984 5.981 5.594
PWD/PhJ both 5.2458 0.0956 5.4339 5.0578




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA