Project measures / variables set:   Threadgill2   APAP50

ID, description, units MPD:39609   APAP50   serum acetaminophen (APAP), 50 mg/mL dose acetaminophen   [µg/mL]  
acetaminophen study
Measures
• baseline    • 0.5h    • 1h    • 2h    • 3h    • 6h
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Comparisontimecourse, same cohort
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Threadgill2 - serum acetaminophen (APAP), 50 mg/mL dose acetaminophen



  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   strain 4 28.0289 7.0072 0.7341 0.5812
between   Residuals 17 162.2609 9.5448
within   group 5 241.3836 48.2767 14.6187 < 0.0001
within   group:strain 20 67.3412 3.3671 1.0196 0.4492
within   Residuals 85 280.7039 3.3024

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested		SexAge
Threadgill2 39609 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 50 mg/mL dose acetaminophen   [µg/mL]   baseline  APAP50_0 inbred 5 m 6-8wks
Threadgill2 39610 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 50 mg/mL dose acetaminophen   [µg/mL]   0.5h  APAP50_0.5 inbred 5 m 6-8wks
Threadgill2 39612 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 50 mg/mL dose acetaminophen   [µg/mL]   1h  APAP50_1 inbred 5 m 6-8wks
Threadgill2 39613 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 50 mg/mL dose acetaminophen   [µg/mL]   2h  APAP50_2 inbred 5 m 6-8wks
Threadgill2 39614 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 50 mg/mL dose acetaminophen   [µg/mL]   3h  APAP50_3 inbred 5 m 6-8wks
Threadgill2 39615 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 50 mg/mL dose acetaminophen   [µg/mL]   6h  APAP50_6 inbred 5 m 6-8wks



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