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Project measures / variables set:   Rusyn2   DCA_tce

ID, description, units MPD:36167   DCA_tce   dichloroacetic acid (serum DCA x 10-3)   [nmol/mL]  
trichloroethylene study
Measures
• time after treatment: 2h    • 8h    • 24h
Data set, strains Rusyn2   inbred   15 strains     sex: m     age: 7wks
Procedure drug and metabolite quantification
Comparisontimecourse but different cohorts
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Rusyn2 - dichloroacetic acid (serum DCA x 10-3)




  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary     

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
time 2 339962.9718 169981.4859 6.1264 0.0039
strain 10 343092.0188 34309.2019 1.2366 0.2879
time:strain 20 558508.1963 27925.4098 1.0065 0.4692
Residuals 58 1609250.0 27745.6897

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested
SexAge
Rusyn2 36167 drug and metabolite quantification trichloroethylene dichloroacetic acid (serum DCA x 10-3)   [nmol/mL]   2h after treatment  DCA_2_tce inbred 15 m 7wks
Rusyn2 36168 drug and metabolite quantification trichloroethylene dichloroacetic acid (serum DCA x 10-3)   [nmol/mL]   8h after treatment  DCA_8_tce inbred 15 m 7wks
Rusyn2 36169 drug and metabolite quantification trichloroethylene dichloroacetic acid (serum DCA x 10-3)   [nmol/mL]   24h after treatment  DCA_24_tce inbred 15 m 7wks