Project measures / variables set:   Threadgill2   APAP300

ID, description, units MPD:39632   APAP300   serum acetaminophen (APAP), 300 mg/mL dose acetaminophen   [µg/mL]  
acetaminophen study
Measures
• baseline    • 0.5h    • 1h    • 2h    • 3h    • 6h
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Comparisontimecourse, same cohort
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Threadgill2 - serum acetaminophen (APAP), 300 mg/mL dose acetaminophen



  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   strain 4 25351.8664 6337.9666 7.1216 0.0013
between   Residuals 18 16019.2425 889.9579
within   group 5 103446.1486 20689.2297 108.4808 < 0.0001
within   group:strain 20 14245.5488 712.2774 3.7347 < 0.0001
within   Residuals 90 17164.6041 190.7178

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested		SexAge
Threadgill2 39632 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 300 mg/mL dose acetaminophen   [µg/mL]   baseline  APAP300_0 inbred 5 m 6-8wks
Threadgill2 39633 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 300 mg/mL dose acetaminophen   [µg/mL]   0.5h  APAP300_0.5 inbred 5 m 6-8wks
Threadgill2 39634 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 300 mg/mL dose acetaminophen   [µg/mL]   1h  APAP300_1 inbred 5 m 6-8wks
Threadgill2 39635 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 300 mg/mL dose acetaminophen   [µg/mL]   2h  APAP300_2 inbred 5 m 6-8wks
Threadgill2 39636 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 300 mg/mL dose acetaminophen   [µg/mL]   3h  APAP300_3 inbred 5 m 6-8wks
Threadgill2 39637 drug and metabolite quantification acetaminophen serum acetaminophen (APAP), 300 mg/mL dose acetaminophen   [µg/mL]   6h  APAP300_6 inbred 5 m 6-8wks



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