MPD: Project measures / variables set: Noll1 IgG2ac

Project measures / variables set: Noll1 IgG2ac

ID, description, units	MPD:112612 IgG2ac immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection [AUC] influenza A (H1N1) virus study
Measures	• post-infection: • day 7 • day 10 • day 15 • day 29 • day 45
Data set, strains	Noll1 CC RIX 46 strains sex: f age: 8-12 wks
Procedure	immunoglobulin quantification
Comparison	timecourse but different cohorts
Ontology mappings	VT:0008496 blood immunoglobulin G2a amount VT:0008897 blood immunoglobulin G2c amount MA:0002502 serum MP:0020176 abnormal IgG2a level MP:0020178 abnormal IgG2c level

Values Means Δ Means Z-scores

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Noll1 - immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
post-infection	4	2237.7882	559.447	327.2697	< 0.0001
post-infection:strain	44	236.669	5.3788	3.1466	< 0.0001
Residuals	167	285.476	1.7094
strain	11	214.8018	19.5274	11.4233	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Noll1	112612	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection [AUC] day 7 IgG2ac_d7	CC RIX	39	f	8-12 wks
Noll1	112613	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection [AUC] day 10 IgG2ac_d10	CC RIX	39	f	8-12 wks
Noll1	112614	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection [AUC] day 15 IgG2ac_d15	CC RIX	34	f	8-12 wks
Noll1	112615	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection [AUC] day 29 IgG2ac_d29	CC RIX	25	f	8-12 wks
Noll1	112616	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection [AUC] day 45 IgG2ac_d45	CC RIX	35	f	8-12 wks