MPD: Project measures / variables set: Shockley1 HDL

Project measures / variables set: Shockley1 HDL

ID, description, units	MPD:33407 HDL HDL cholesterol (HDL) [mg/dL] high-fat diet study
Measures	• control diet • high-fat diet • difference
Data set, strains	Shockley1 inbred 10 strains sex: both age: 10-13wks
Procedure	lipid profile
Comparison	control group vs. treated group
Ontology mappings	VT:0000184 blood HDL cholesterol amount MA:0002502 serum MP:0000184 abnormal circulating HDL cholesterol level

Values Means Δ Means Z-scores

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Shockley1 - HDL cholesterol (HDL)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	36546.889	36546.889	200.7358	< 0.0001
sex	1	34359.7419	34359.7419	188.7228	< 0.0001
strain	9	184384.58	20487.1756	112.5269	< 0.0001
group:sex	1	220.6905	220.6905	1.2122	0.2726
group:strain	9	34986.5222	3887.3914	21.3517	< 0.0001
sex:strain	9	12868.1203	1429.7911	7.8532	< 0.0001
group:sex:strain	9	4604.6116	511.6235	2.8101	0.0043
Residuals	158	28766.214	182.0646

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Shockley1	33407	lipid profile	high-fat diet	HDL cholesterol (HDL) [mg/dL] control diet HDL	inbred	10	both	10-13wks
Shockley1	33437	lipid profile	high-fat diet	HDL cholesterol (HDL) [mg/dL] high-fat diet HDL_fat	inbred	10	both	10-13wks
Shockley1	33857	lipid profile	high-fat diet	HDL cholesterol (HDL) [mg/dL] difference HDLD_diff	inbred	10	both	10-13wks	(supplemental / summary measure)