Benton CS, Miller BH, Skwerer S, Suzuki O, Schultz LE, Cameron MD, Marron JS, Pletcher MT, Wiltshire T. Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains.
Psychopharmacology (Berl). 2012 May;221(2):297-315. Epub 2011 Nov 24.
Tim Wiltshire University of North Carolina, Chapel Hill, NC|
Mathew T Pletcher Pfizer Global Research and Development, Groton, CT
|Participants||Benton CS, Miller BH, Skwerer S, Suzuki O, Schultz LE, Cameron MD, Marron JS|
|Contact||Tim Wiltshire firstname.lastname@example.org
|Part of a series:||
Behavior phenotype data see Pletcher1
• Behavior phenotype data (fluoxetine study) (this project) Wiltshire2
• Neurobiochemical analyte data see Wiltshire3
|Acknowledgements||Funding provided by NIH MH077251 and MH084528; State of Florida |
Behavioral testing was conducted at The Scripps Research Institute.
In fulfillment of NIH requirements that all information is made promptly and freely available to the research community, data are deposited in the MPD when complete.
|Phenotype strain survey data set|
|MPD identifiers||Wiltshire2 MPD:380|
|No updates/corrections. Initial release date: 12/2011.|
Click above to copy-paste the entire citation for this MPD web page.
|Summary of procedures that were conducted|
|• tail suspension test||Immobility. Fluoxetine-treated vs. control. 5 min test.|
|• open field test||Locomotor activity, exploratory and anxiety-related behavior. Fluoxetine-treated vs. control. 7 min test.|
|• drug and metabolite quantification||Fluoxetine and norfluoxetine concentration (serum) after fluoxetine.|