Shockley1: Diet effects on blood chemistry and lipids in 10 inbred strains of mice (2008)

Shockley KR, Witmer D, Burgess-Herbert SL, Paigen B, Churchill GA. Effects of atherogenic diet on hepatic gene expression across mouse strains. Physiol Genomics. 2009 Nov 6;39(3):172-82. Epub 2009 Aug 11.   PubMed 19671657     FullText

Shockley1 downloads
• Download Shockley1 project data set     animal data, as uploaded
• Download Shockley1 animal data matrix     with factor-related expansion applied as necessary
• Download Shockley1 strain means, SD, N, etc.     one row per strain/sex/measure
• Shockley1 supplementary data
Investigators Keith Shockley       The Jackson Laboratory,  Bar Harbor, ME
Beverly Paigen       The Jackson Laboratory,  Bar Harbor, ME
Gary A Churchill       The Jackson Laboratory,  Bar Harbor, ME
Participants Witmer D, Burgess-Herbert SL
ContactKeith Shockley     Lab web site
Affiliated CenterCenter for Genome Dynamics (CGD)
Part of a series: • Phenotype data   (this project) Shockley1
AcknowledgementsFunding provided by NIH GM076468, HL77796, HL74086; HG003968

Additional funding was provided by Novartis Institutes for Biomedical Research (Boston, MA), Howard Hughes Medical Institute, Betterment Fund Scholarship Endowment, Clarence Cook Little Scholarship Fund, LG Balfour Foundation, and Horace W. Goldsmith Foundation.
Project type Phenotype strain survey data set
MPD identifiersShockley1     MPD:334
Data changelog 1 update/correction.       Initial release date: 02/2010.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
An investigation of metabolic response to atherogenic (high-fat) diet. Two cohorts: control diet group and high-fat diet group. Animals were evaluated using Beckman CX5 Synchron Delta Chemistry Autoanalyzer.

Procedures conducted:
• body weight  High-fat diet for 4wks vs. control.
• lipid profile  Cholesterol, HDL, triglycerides, fatty acids. High-fat diet (4wks) vs. control. 5h fast, serum.
• metabolic panel  Clinical blood chemistry measures (serum). High-fat diet (4wks) vs. control.

Mice: inbred   10 strains   ♀♂   age 10-13wks   2 experimental groups