Phenotype measures set:   Threadgill1   AST

ID, description, units MPD:19410   AST   aspartate transaminase (serum AST)   [IU/L]
acetaminophen study
Measures • dose (mg/kg): control    • 100    • 200    • 300
Data set, strains Threadgill1   inbred w/CC7   37 strains     sex: m     age: 8-17wks
Procedure metabolic panel
Comparisoncontrol group as well as two or more dosage groups
Ontology mappings



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Threadgill1 - aspartate transaminase (serum AST)


Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary     

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
dose 3 1355681884.9947 451893961.6649 21.9133 < 0.0001
strain 6 688724715.0612 114787452.5102 5.5663 0.0001
dose:strain 18 1341394576.2023 74521920.9001 3.6137 0.0001
Residuals 63 1299181743.5 20621932.4365

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelStrains
tested
SexAge
Threadgill1 19410 metabolic panel acetaminophen aspartate transaminase (serum AST)   [IU/L]   control   AST_ctrl inbred w/CC7 37 m 8-17wks
Threadgill1 19411 metabolic panel acetaminophen aspartate transaminase (serum AST)   [IU/L]   dose: 100 mg/kg   AST_Rx100 inbred w/CC7 7 m 8-17wks
Threadgill1 19441 metabolic panel acetaminophen aspartate transaminase (serum AST)   [IU/L]   dose: 200 mg/kg   AST_Rx200 inbred w/CC7 8 m 8-17wks
Threadgill1 19471 metabolic panel acetaminophen aspartate transaminase (serum AST)   [IU/L]   dose: 300 mg/kg   AST_Rx300 inbred w/CC7 37 m 8-17wks