MPD: Phenotype measures mapped to MA:0000415, lung

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Ackerman1:1	Ackerman1	ventilator	methacholine	individual pulmonary resistance values, a percentage of baseline for the 100 µg/kg dose [%] RL100 15601	QTL population		f	7-8wks	N=372	2005

Ackerman1:2	Ackerman1	ventilator	methacholine	individual pulmonary resistance, a percentage of baseline for the 330 µg/kg dose [%] RL330 15602	QTL population		f	7-8wks	N=372	2005

Ackerman1:3	Ackerman1	ventilator	methacholine	individual pulmonary resistance, a percentage of baseline for the 1000 µg/kg dose [%] RL1000 15603	QTL population		f	7-8wks	N=372	2005

Ackerman1:4	Ackerman1	ventilator	methacholine	individual pulmonary resistance, a percentage of baseline for the 3300 µg/kg dose [%] RL3300 15604	QTL population		f	7-8wks	N=372	2005

Ackerman1:5	Ackerman1	ventilator	methacholine	effective doses of methacholine required for a 1.50-fold increase in R_L), log transformed [log(n)] logED150 15605	QTL population		f	7-8wks	N=372	2005

Berndt1:1	Berndt1	ventilator	(none)	airway resistance (naive, untreated, H₂O pressure) [cm/mL/s] airway_res 34201	inbred	37	both	9-12wks	N=9	2010

Berndt1:10	Berndt1	ventilator	methacholine	airway resistance (H₂O pressure) [cm/mL/s] airway_res_series 34210 baseline MCh challenge (mg/mL): 1 3 10 30	inbred	37	both	9-12wks	N=8	2010

Berndt1:21	Berndt1	ventilator	methacholine	airway resistance (as % of baseline, H₂O pressure) [%] pct_res 34221 MCh challenge (mg/mL): 1 3 10 30	inbred	37	both	9-12wks	N=8	2010

Berndt2:1	Berndt2	plethysmography	methacholine	minute ventilation [mL/min] min_vent 35101 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:8	Berndt2	plethysmography	methacholine	breath frequency [n/min] breath_freq 35108 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:14	Berndt2	plethysmography	methacholine	inspiratory phase [s] inspiratory 35114 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:21	Berndt2	plethysmography	methacholine	expiratory phase [s] expiratory 35121 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:28	Berndt2	plethysmography	methacholine	respiratory cycle [s] tot_respi 35128 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:34	Berndt2	plethysmography	methacholine	duty cycle [ratio] duty_cycle 35134 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:41	Berndt2	plethysmography	methacholine	inspiratory flow rate [mL/kg/s] insp_flow 35141 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:48	Berndt2	plethysmography	methacholine	expiratory flow rate [mL/kg/s] exp_flow 35148 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:54	Berndt2	plethysmography	methacholine	respiratory flow rate [mL/kg/s] resp_flow 35154 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:61	Berndt2	plethysmography	methacholine	enhanced pause penh 35161 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:68	Berndt2	plethysmography	methacholine	tidal volume [mL] tidal_vol 35168 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:81	Berndt2	ventilator	methacholine	airway resistance (H₂0 pressure) [cm/mL/s] airway_res 35181 saline 1 MCh 3 MCh 10 MCh 30 MCh response index	inbred	29	both	9-12wks	N=9	2010

Berndt2:91	Berndt2	ventilator	methacholine	lung tissue dynamic elastance (H₂0 pressure) [cm/mL] airway_elas 35191 saline 1 MCh 3 MCh 10 MCh 30 MCh response index	inbred	29	both	9-12wks	N=9	2010

Berndt4:1	Berndt4	histopathology	(none)	lung adenoma frequency [%] adenoma_freq 48301	inbred	28	both	90wks	N=10	2011

Berndt4:2	Berndt4	histopathology	(none)	lung adenoma severity score [score] adenoma_score 48302	inbred	28	both	90wks	N=10	2011

Bopp1:6	Bopp1	health assessment	Plasmodium berghei	percentage of parasites in lungs relative to all organs tested [%] luciferase_lungs 36406	inbred	28	both	8-12wks	N=2	2010

Ferris1:7	Ferris1	histopathology	influenza A (H1N1) virus	virus-induced airway inflammation, day 4 post-infection (score 0-3) [score] airway_inflam 47607	CC pre w/par	161	f	8-16wks	N=1	2012

Ferris1:8	Ferris1	histopathology	influenza A (H1N1) virus	virus-induced airway neutrophils, day 4 post-infection (score 0-3) [score] airway_neut 47608	CC pre w/par	140	f	8-16wks	N=1	2012

Ferris1:9	Ferris1	histopathology	influenza A (H1N1) virus	virus-induced airway damage, day 4 post-infection (score 0-3) [score] airway_damage 47609	CC pre w/par	160	f	8-16wks	N=1	2012

Ferris1:10	Ferris1	histopathology	influenza A (H1N1) virus	virus-induced vascular inflammation (lung), day 4 post-infection (score 0-3) [score] vascular_inflam 47610	CC pre w/par	161	f	8-16wks	N=1	2012

Ferris1:11	Ferris1	histopathology	influenza A (H1N1) virus	virus-induced alveolar inflammation, day 4 post-infection (score 0-3) [score] alveolar_inflam 47611	CC pre w/par	161	f	8-16wks	N=1	2012

Ferris1:12	Ferris1	histopathology	influenza A (H1N1) virus	virus-induced alveolar damage, day 4 post-infection (score 0-3) [score] alveolar_damage 47612	CC pre w/par	161	f	8-16wks	N=1	2012

Ferris1:13	Ferris1	histopathology	influenza A (H1N1) virus	virus-induced pulmonary edema, day 4 post-infection (score 0-3) [score] pulmonary_edema 47613	CC pre w/par	138	f	8-16wks	N=1	2012

GMC12:11	GMC12	echocardiography	(none)	respiration rate [n/min] resp_rate 56111	inbred w/CC8	8	both	14-15wks	N=15	2018

GMC19:11	GMC19	ventilator	(none)	residual volume (RV) in the lungs after a maximal exhalation [mL] residual_vol 56811	inbred w/CC8	7	f	21-22wks	N=3	2018

GMC19:12	GMC19	ventilator	(none)	expiratory reserve volume (ERV), FVC minus IC [mL] expiratory_vol 56812	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:13	GMC19	ventilator	(none)	forced expiratory volume expired in first 100 ms of fast expiration (FEV100) [mL] forced_expiratory_vol 56813	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:14	GMC19	ventilator	(none)	tidal volume (TV) of air into or out of lungs during quiet breathing [mL] tidal_vol 56814	inbred w/CC8	8	f	21-22wks	N=4	2018

GMC19:21	GMC19	ventilator	(none)	total lung capacity (TLC), volume in the lungs at maximal inflation, sum of VC and RV [mL] lung_capacity 56821	inbred w/CC8	7	f	21-22wks	N=3	2018

GMC19:22	GMC19	ventilator	(none)	vital capacity (VC), volume of air breathed out after deepest inhalation [mL] vital_capacity 56822	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:23	GMC19	ventilator	(none)	forced vital capacity (FVC), volume expired during fast expiration [mL] forced_capacity 56823	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:24	GMC19	ventilator	(none)	inspiratory capacity (IC), volume inspired during slow inspiration [mL] inspiratory_capacity 56824	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:25	GMC19	ventilator	(none)	functional residual capacity (FRC), volume in lungs at end-expiratory position [mL] residual_capacity 56825	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:31	GMC19	ventilator	(none)	lung compliance (chord compliance) (H₂O pressure) [mL/cm] chord_compliance 56831	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:32	GMC19	ventilator	(none)	dynamic compliance (C) of respiratory system with breathing rate of 130/min (H₂O pressure) [mL/cm] dynamic_compliance 56832	inbred w/CC8	8	f	21-22wks	N=4	2018

GMC19:41	GMC19	ventilator	(none)	respiratory system resistance (H₂O pressure) [cm/mL/s] resistance 56841	inbred w/CC8	8	f	21-22wks	N=4	2018

GMC19:42	GMC19	ventilator	(none)	peak expiratory flow (PEF) [mL/s] peak_flow 56842	inbred w/CC8	8	f	21-22wks	N=3	2018

Graham2:6	Graham2	in vitro assay	SARS-CoV	lung viral load titer (log10(x+1)), post infection [log(n)] log_titer 113790 post infection: day 2 day 4	CC RIX	111	f	8-10wks		2021

Graubert1:16	Graubert1	histopathology	ENU	lung adenoma frequency rate [score] adenoma_lung 11616 control ENU	inbred	20	both	13-68wks	N=6	2006

Graubert1:17	Graubert1	histopathology	ENU	lung carcinoma frequency rate [score] carcinoma_lung 11617 control ENU	inbred	20	both	13-68wks	N=6	2006

Hackstein1:1	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage total leukocyte count (x 10³) [n] BAL 49101	inbred	5	m	7-11wks	N=5	2012

Hackstein1:2	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage macrophages (percentage of leukocytes) [%] BAL_MAC 49102	inbred	5	m	7-11wks	N=5	2012

Hackstein1:3	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage dendritic cells (percentage of CD45+ cells) [%] DC 49103	inbred	5	m	7-11wks	N=9	2012

Hackstein1:4	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage plasmacytoid dendritic cells (percentage of CD45+ cells) [%] DC_plasmacytoid 49104	inbred	5	m	7-11wks	N=9	2012

Hackstein1:5	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage monocytic dendritic cells (percentage of CD45+ cells) [%] DC_monocytic 49105	inbred	5	m	7-11wks	N=9	2012

Hackstein1:6	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD103+ dendritic cells (percentage of CD45+ cells) [%] DC_103 49106	inbred	5	m	7-11wks	N=9	2012

Hackstein1:7	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD11b^hi MHC^hi dendritic cells (percentage of CD45+ cells) [%] DC_11b 49107	inbred	5	m	7-11wks	N=9	2012

Hackstein1:8	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage Siglec F+ F4/80+ macrophages (percentage of CD45+ cells) [%] MAC 49108	inbred	5	m	7-11wks	N=9	2012

Hackstein1:9	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage neutrophils (percentage of CD45+ cells) [%] NEUT 49109	inbred	5	m	7-11wks	N=9	2012

Hackstein1:10	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage eosinophils (percentage of CD45+ cells) [%] EOS 49110	inbred	5	m	7-11wks	N=9	2012

Hackstein1:11	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage Lin^neg CD90+ innate cells (percentage of CD45+ cells) [%] Lin_neg_90_plus 49111	inbred	5	m	7-11wks	N=6	2012

Hackstein1:12	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage Lin^neg CD90^- innate cells (percentage of CD45+ cells) [%] Lin_neg_90_neg 49112	inbred	5	m	7-11wks	N=6	2012

Hackstein1:13	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD19+ B cells (percentage of CD45+ cells) [%] B_cells 49113	inbred	5	m	7-11wks	N=8	2012

Hackstein1:14	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ T cells (percentage of CD45+ cells) [%] T_CD3 49114	inbred	5	m	7-11wks	N=9	2012

Hackstein1:15	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD8+ T cells (percentage of CD45+ cells) [%] T_CD8 49115	inbred	5	m	7-11wks	N=9	2012

Hackstein1:16	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD4+ T cells (percentage of CD45+ cells) [%] T_CD4 49116	inbred	5	m	7-11wks	N=9	2012

Hackstein1:17	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD4+ CD25+ T cells (percentage of CD45+ cells) [%] T_CD4_25 49117	inbred	5	m	7-11wks	N=8	2012

Hackstein1:18	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD4+ CD25^hi Treg cells (percentage of CD45+ cells) [%] T_CD4_25hi 49118	inbred	5	m	7-11wks	N=5	2012

Hackstein1:19	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD4+ CD25^hi Foxp3+ Treg cells (percentage of CD45+ cells) [%] T_CD4_foxp3 49119	inbred	5	m	7-11wks	N=5	2012

Hackstein1:20	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD4+ CD25^hi Foxp3+ CD39+ Treg cells (percentage of CD45+ cells) [%] T_CD4_39 49120	inbred	5	m	7-11wks	N=5	2012

Hackstein1:21	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ gamma-delta T cells (percentage of CD45+ cells) [%] T_gd 49121	inbred	5	m	7-11wks	N=9	2012

Hackstein1:22	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD49+ natural killer (NK) cells (percentage of CD45+ cells) [%] NK 49122	inbred	5	m	7-11wks	N=9	2012

Haston1:1	Haston1	health assessment	radiation	number of days in the absence of respiratory distress [d] survival 48801	inbred	26	both	15-36wks	N=7	2012

Haston1:2	Haston1	histopathology	radiation	percentage of lung surface covered by fibrotic scar [%] fibrosis 48802	inbred	26	both	15-36wks	N=6	2012

Haston1:3	Haston1	bronchoalveolar lavage assessment	radiation	percentage of macrophages in bronchoalveolar lavage [%] BAL_mac 48803	inbred	26	both	15-36wks	N=6	2012

Haston1:4	Haston1	bronchoalveolar lavage assessment	radiation	percentage of lymphocytes in bronchoalveolar lavage [%] BAL_lym 48804	inbred	26	both	15-36wks	N=6	2012

Haston1:5	Haston1	bronchoalveolar lavage assessment	radiation	percentage of neutrophils in bronchoalveolar lavage [%] BAL_neut 48805	inbred	26	both	15-36wks	N=6	2012

Haston1:6	Haston1	histopathology	radiation	average number of mast cells per mm² of lung tissue [n] mast_cells 48806	inbred	25	both	15-36wks	N=6	2012

Haston1:7	Haston1	histopathology	radiation	inflammation index (0=no alveolitis, 6=severe alveolitis) [score] alveolitis 48807	inbred	26	both	15-36wks	N=6	2012

Hunter1:6	Hunter1	histopathology	(none)	number of pulmonary metastases [n] mets 6006	MMTV PyVT transgenic	28	f		N=19	1998

Hunter1:7	Hunter1	histopathology	(none)	area of pulmonary metastases (x 10³) [µm²] met_area 6007	MMTV PyVT transgenic	28	f		N=14	1998

Hunter1:8	Hunter1	histopathology	(none)	total lung area (x 10³) [µm²] tot_area 6008	MMTV PyVT transgenic	28	f		N=14	1998

Hunter1:9	Hunter1	histopathology	(none)	number of pulmonary metastases per total lung area (x 10^-9) [n/µm²] ratio_mta 6009	MMTV PyVT transgenic	28	f		N=14	1998

Hunter1:10	Hunter1	histopathology	(none)	area of pulmonary metastases per number of metastases [µm²/n] met_size 6010	MMTV PyVT transgenic	28	f		N=14	1998

Hunter1:11	Hunter1	histopathology	(none)	area of pulmonary metastases per total lung area [ratio] ratio_ata 6011	MMTV PyVT transgenic	28	f		N=14	1998

Schughart4:83	Schughart4	in vitro assay	influenza A (H3N2) virus	viral load in lungs (titer, FFU per lung) log10 (x+1) [log(n)] titer_trt 58783 days post-infection: 3 5 8	inbred w/CC8	8	f	8-12wks	N=5	2016

Schulz1:6	Schulz1	ventilator	(none)	inspiratory capacity (+ 25 cm H₂O) [µL] IC 1606	inbred	7	both	12-14wks	N=15	2000

Schulz1:7	Schulz1	ventilator	(none)	functional residual capacity [µL] FRC 1607	inbred	7	both	12-14wks	N=15	2000

Schulz1:8	Schulz1	ventilator	(none)	total lung capacity [µL] TLC 1608	inbred	7	both	12-14wks	N=15	2000

Schulz1:9	Schulz1	ventilator	(none)	vital capacity [µL] VC 1609	inbred	7	both	12-14wks	N=15	2000

Schulz1:10	Schulz1	ventilator	(none)	dynamic compliance of respiratory system with breathing rate of 130 per min (H₂O pressure) [µL/cm] Cdyn130 1610	inbred	7	both	12-14wks	N=15	2000

Schulz1:11	Schulz1	ventilator	(none)	static compliance of respiratory system (H₂O pressure) [µL/cm] CRS 1611	inbred	7	both	12-14wks	N=15	2000

Schulz1:12	Schulz1	ventilator	(none)	static compliance of lung (H₂O pressure) [µL/cm] CL 1612	inbred	7	both	12-14wks	N=14	2000

Schulz1:13	Schulz1	ventilator	(none)	respiratory system resistance with breathing rate of 130 per min (H₂O pressure) [cm/mL/s] R 1613	inbred	7	both	12-14wks	N=15	2000

Schulz1:14	Schulz1	ventilator	(none)	specific respiratory system resistance with breathing rate of 130 per min related to total lung capacity (H₂O pressure) [cm⋅s] sR 1614	inbred	7	both	12-14wks	N=15	2000

Schulz1:16	Schulz1	ventilator	(none)	intrapulmonary gas mixing: slope of phase III (Hg pressure) [mm/mL] slope 1616	inbred	7	both	12-14wks	N=15	2000

Schulz1:17	Schulz1	ventilator	(none)	alveolar volume [µL] VA 1617	inbred	7	both	12-14wks	N=14	2000

Schulz1:18	Schulz1	ventilator	(none)	diffusing capacity: carbon monoxide [µmol/min/hPa] D_CO 1618	inbred	7	both	12-14wks	N=14	2000

Schulz1:19	Schulz1	ventilator	(none)	specific diffusing capacity: carbon monoxide to alveolar volume [µmol/min/hPa/mL] sD_CO 1619	inbred	7	both	12-14wks	N=14	2000

Schulz1:20	Schulz1	ventilator	(none)	functional residual capacity to total lung capacity [µL/µL] ratio_FRC_TLC 1620	inbred	7	both	12-14wks	N=15	2000

Schulz1:22	Schulz1	ventilator	(none)	total lung capacity to body weight [µL/g] ratio_TLC_bw 1622	inbred	7	both	12-14wks	N=15	2000

Schulz1:23	Schulz1	ventilator	(none)	vital capacity to body weight [L/g] ratio_VC_bw 1623	inbred	7	both	12-14wks	N=15	2000

Schulz1:24	Schulz1	ventilator	(none)	functional residual capacity to body weight [µL/g] ratio_FRC_bw 1624	inbred	7	both	12-14wks	N=14	2000

Schulz1:26	Schulz1	ventilator	(none)	static compliance of lung related to total lung capacity (H₂O pressure) [1/cm] ratio_CL_TLC 1626	inbred	7	both	12-14wks	N=14	2000

Schulz1:27	Schulz1	ventilator	(none)	dynamic compliance of respiratory system (breathing rate 130/min) related to total lung capacity (H₂O pressure) [1/cm] ratio_Cdyn130_TLC 1627	inbred	7	both	12-14wks	N=15	2000

Schulz1:30	Schulz1	ventilator	(none)	Fowler dead space volume to total lung capacity [µL/µL] ratio_VDF_TLC 1630	inbred	7	both	12-14wks	N=15	2000

Schulz1:31	Schulz1	ventilator	(none)	Fowler dead space volume to body weight [µL/g] ratio_VDF_bw 1631	inbred	7	both	12-14wks	N=14	2000

Schulz1:32	Schulz1	ventilator	(none)	Fowler dead space volume [µL] VDF 1632	inbred	7	both	12-14wks	N=15	2000

Schwartz2:1	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar eosinophils (percentage of total lavage cells), pre-challenge [%] pctEOS0 9801 pre-test: control OVA-sensitized	inbred	8	m	6-8wks	N=3	2001

Schwartz2:2	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar eosinophils (percentage of total lavage cells), 24h post-challenge [%] pctEOS24 9802 24h post: control OVA-sensitized	inbred	8	m	6-8wks	N=5	2001

Schwartz2:3	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar eosinophils (percentage of total lavage cells), 48h post-challenge [%] pctEOS48 9803 48h post: control OVA-sensitized	inbred	8	m	6-8wks	N=5	2001

Schwartz2:4	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar eosinophils (percentage of total lavage cells), 72h post-challenge [%] pctEOS72 9804 72h post: control OVA-sensitized	inbred	8	m	6-8wks	N=5	2001

Schwartz2:21	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar lymphocytes (percentage of total lavage cells), pre-challenge [%] pctLYM0 9821 pre-test: control OVA-sensitized	inbred	8	m	6-8wks	N=3	2001

Schwartz2:22	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar lymphocytes (percentage of total lavage cells), 24h post-challenge [%] pctLYM24 9822 24h post: control OVA-sensitized	inbred	8	m	6-8wks	N=5	2001

Schwartz2:23	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar lymphocytes (percentage of total lavage cells), 48h post-challenge [%] pctLYM48 9823 48h post: control OVA-sensitized	inbred	8	m	6-8wks	N=5	2001

Schwartz2:24	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar lymphocytes (percentage of total lavage cells), 72h post-challenge [%] pctLYM72 9824 72h post: control OVA-sensitized	inbred	8	m	6-8wks	N=5	2001

Schwartz2:41	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar neutrophils (percentage of total lavage cells), pre-challenge [%] pctNEUT0 9841 pre-test: control OVA-sensitized	inbred	8	m	6-8wks	N=3	2001

Schwartz2:42	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar neutrophils (percentage of total lavage cells), 24h post-challenge [%] pctNEUT24 9842 24h post: control OVA-sensitized	inbred	8	m	6-8wks	N=5	2001

Schwartz2:43	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar neutrophils (percentage of total lavage cells), 48h post-challenge [%] pctNEUT48 9843 48h post: control OVA-sensitized	inbred	8	m	6-8wks	N=5	2001

Schwartz2:44	Schwartz2	bronchoalveolar lavage assessment	ovalbumin	alveolar neutrophils (percentage of total lavage cells), 72h post-challenge [%] pctNEUT72 9844 72h post: control OVA-sensitized	inbred	8	m	6-8wks	N=5	2001

Ackerman1

ventilator

methacholine

individual pulmonary resistance values, a percentage of baseline for the 100 µg/kg dose [%] RL100 15601

QTL population

f

7-8wks

N=372

2005

Ackerman1

ventilator

methacholine

individual pulmonary resistance, a percentage of baseline for the 330 µg/kg dose [%] RL330 15602

QTL population

f

7-8wks

N=372

2005

Ackerman1

ventilator

methacholine

individual pulmonary resistance, a percentage of baseline for the 1000 µg/kg dose [%] RL1000 15603

QTL population

f

7-8wks

N=372

2005

Ackerman1

ventilator

methacholine

individual pulmonary resistance, a percentage of baseline for the 3300 µg/kg dose [%] RL3300 15604

QTL population

f

7-8wks

N=372

2005

Ackerman1

ventilator

methacholine

effective doses of methacholine required for a 1.50-fold increase in R_L), log transformed [log(n)] logED150 15605

QTL population

f

7-8wks

N=372

2005

Berndt1

ventilator

(none)

airway resistance (naive, untreated, H₂O pressure) [cm/mL/s] airway_res 34201

inbred

37

both

9-12wks

N=9

2010

Berndt1

ventilator

methacholine

airway resistance (H₂O pressure) [cm/mL/s] airway_res_series 34210 baseline MCh challenge (mg/mL): 1 3 10 30

inbred

37

both

9-12wks

N=8

2010

Berndt1

ventilator

methacholine

airway resistance (as % of baseline, H₂O pressure) [%] pct_res 34221 MCh challenge (mg/mL): 1 3 10 30

inbred

37

both

9-12wks

N=8

2010

Berndt2

plethysmography

methacholine

minute ventilation [mL/min] min_vent 35101 saline 5 MCh 10 MCh 20 MCh response index

inbred

29

both

9-12wks

N=8

2010

Berndt2

plethysmography

methacholine

breath frequency [n/min] breath_freq 35108 saline 5 MCh 10 MCh 20 MCh response index

inbred

29

both

9-12wks

N=8

2010

Berndt2

plethysmography

methacholine

inspiratory phase [s] inspiratory 35114 saline 5 MCh 10 MCh 20 MCh response index

inbred

29

both

9-12wks

N=8

2010

Berndt2

plethysmography

methacholine

expiratory phase [s] expiratory 35121 saline 5 MCh 10 MCh 20 MCh response index

inbred

29

both

9-12wks

N=8

2010

Berndt2

plethysmography

methacholine

respiratory cycle [s] tot_respi 35128 saline 5 MCh 10 MCh 20 MCh response index

inbred

29

both

9-12wks

N=8

2010

Berndt2

plethysmography

methacholine

duty cycle [ratio] duty_cycle 35134 saline 5 MCh 10 MCh 20 MCh response index

inbred

29

both

9-12wks

N=8

2010

Berndt2

plethysmography

methacholine

inspiratory flow rate [mL/kg/s] insp_flow 35141 saline 5 MCh 10 MCh 20 MCh response index

inbred

29

both

9-12wks

N=8

2010

Berndt2

plethysmography

methacholine

expiratory flow rate [mL/kg/s] exp_flow 35148 saline 5 MCh 10 MCh 20 MCh response index

inbred

29

both

9-12wks

N=8

2010

Berndt2

plethysmography

methacholine

respiratory flow rate [mL/kg/s] resp_flow 35154 saline 5 MCh 10 MCh 20 MCh response index

inbred

29

both

9-12wks

N=8

2010

Berndt2

plethysmography

methacholine

enhanced pause penh 35161 saline 5 MCh 10 MCh 20 MCh response index

inbred

29

both

9-12wks

N=8

2010

Berndt2

plethysmography

methacholine

tidal volume [mL] tidal_vol 35168 saline 5 MCh 10 MCh 20 MCh response index

inbred

29

both

9-12wks

N=8

2010

Berndt2

ventilator

methacholine

airway resistance (H₂0 pressure) [cm/mL/s] airway_res 35181 saline 1 MCh 3 MCh 10 MCh 30 MCh response index

inbred

29

both

9-12wks

N=9

2010

Berndt2

ventilator

methacholine

lung tissue dynamic elastance (H₂0 pressure) [cm/mL] airway_elas 35191 saline 1 MCh 3 MCh 10 MCh 30 MCh response index

inbred

29

both

9-12wks

N=9

2010

Berndt4

histopathology

(none)

lung adenoma frequency [%] adenoma_freq 48301

inbred

28

both

90wks

N=10

2011

Berndt4

histopathology

(none)

lung adenoma severity score [score] adenoma_score 48302

inbred

28

both

90wks

N=10

2011

Bopp1

health assessment

Plasmodium berghei

percentage of parasites in lungs relative to all organs tested [%] luciferase_lungs 36406

inbred

28

both

8-12wks

N=2

2010

Ferris1

histopathology

influenza A (H1N1) virus

virus-induced airway inflammation, day 4 post-infection (score 0-3) [score] airway_inflam 47607

CC pre w/par

161

f

8-16wks

N=1

2012

Ferris1

histopathology

influenza A (H1N1) virus

virus-induced airway neutrophils, day 4 post-infection (score 0-3) [score] airway_neut 47608

CC pre w/par

140

f

8-16wks

N=1

2012

Ferris1

histopathology

influenza A (H1N1) virus

virus-induced airway damage, day 4 post-infection (score 0-3) [score] airway_damage 47609

CC pre w/par

160

f

8-16wks

N=1

2012

Ferris1

histopathology

influenza A (H1N1) virus

virus-induced vascular inflammation (lung), day 4 post-infection (score 0-3) [score] vascular_inflam 47610

CC pre w/par

161

f

8-16wks

N=1

2012

Ferris1

histopathology

influenza A (H1N1) virus

virus-induced alveolar inflammation, day 4 post-infection (score 0-3) [score] alveolar_inflam 47611

CC pre w/par

161

f

8-16wks

N=1

2012

Ferris1

histopathology

influenza A (H1N1) virus

virus-induced alveolar damage, day 4 post-infection (score 0-3) [score] alveolar_damage 47612

CC pre w/par

161

f

8-16wks

N=1

2012

Ferris1

histopathology

influenza A (H1N1) virus

virus-induced pulmonary edema, day 4 post-infection (score 0-3) [score] pulmonary_edema 47613

CC pre w/par

138

f

8-16wks

N=1

2012

GMC12

echocardiography

(none)

respiration rate [n/min] resp_rate 56111

inbred w/CC8

8

both

14-15wks

N=15

2018

GMC19

ventilator

(none)

residual volume (RV) in the lungs after a maximal exhalation [mL] residual_vol 56811

inbred w/CC8

7

f

21-22wks

N=3

2018

GMC19

ventilator

(none)

expiratory reserve volume (ERV), FVC minus IC [mL] expiratory_vol 56812

inbred w/CC8

8

f

21-22wks

N=3

2018

GMC19

ventilator

(none)

forced expiratory volume expired in first 100 ms of fast expiration (FEV100) [mL] forced_expiratory_vol 56813

inbred w/CC8

8

f

21-22wks

N=3

2018

GMC19

ventilator

(none)

tidal volume (TV) of air into or out of lungs during quiet breathing [mL] tidal_vol 56814

inbred w/CC8

8

f

21-22wks

N=4

2018

GMC19

ventilator

(none)

total lung capacity (TLC), volume in the lungs at maximal inflation, sum of VC and RV [mL] lung_capacity 56821

inbred w/CC8

7

f

21-22wks

N=3

2018

GMC19

ventilator

(none)

vital capacity (VC), volume of air breathed out after deepest inhalation [mL] vital_capacity 56822

inbred w/CC8

8

f

21-22wks

N=3

2018

GMC19

ventilator

(none)

forced vital capacity (FVC), volume expired during fast expiration [mL] forced_capacity 56823

inbred w/CC8

8

f

21-22wks

N=3

2018

GMC19

ventilator

(none)

inspiratory capacity (IC), volume inspired during slow inspiration [mL] inspiratory_capacity 56824

inbred w/CC8

8

f

21-22wks

N=3

2018

GMC19

ventilator

(none)

functional residual capacity (FRC), volume in lungs at end-expiratory position [mL] residual_capacity 56825

inbred w/CC8

8

f

21-22wks

N=3

2018

GMC19

ventilator

(none)

lung compliance (chord compliance) (H₂O pressure) [mL/cm] chord_compliance 56831

inbred w/CC8

8

f

21-22wks

N=3

2018

GMC19

ventilator

(none)

dynamic compliance (C) of respiratory system with breathing rate of 130/min (H₂O pressure) [mL/cm] dynamic_compliance 56832

inbred w/CC8

8

f

21-22wks

N=4

2018

GMC19

ventilator

(none)

respiratory system resistance (H₂O pressure) [cm/mL/s] resistance 56841

inbred w/CC8

8

f

21-22wks

N=4

2018

GMC19

ventilator

(none)

peak expiratory flow (PEF) [mL/s] peak_flow 56842

inbred w/CC8

8

f

21-22wks

N=3

2018

Graham2

in vitro assay

SARS-CoV

lung viral load titer (log10(x+1)), post infection [log(n)] log_titer 113790 post infection: day 2 day 4

CC RIX

111

f

8-10wks

2021

Graubert1

histopathology

ENU

lung adenoma frequency rate [score] adenoma_lung 11616 control ENU

inbred

20

both

13-68wks

N=6

2006

Graubert1

histopathology

ENU

lung carcinoma frequency rate [score] carcinoma_lung 11617 control ENU

inbred

20

both

13-68wks

N=6

2006

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage total leukocyte count (x 10³) [n] BAL 49101

inbred

5

m

7-11wks

N=5

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage macrophages (percentage of leukocytes) [%] BAL_MAC 49102

inbred

5

m

7-11wks

N=5

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage dendritic cells (percentage of CD45+ cells) [%] DC 49103

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage plasmacytoid dendritic cells (percentage of CD45+ cells) [%] DC_plasmacytoid 49104

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage monocytic dendritic cells (percentage of CD45+ cells) [%] DC_monocytic 49105

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD103+ dendritic cells (percentage of CD45+ cells) [%] DC_103 49106

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD11b^hi MHC^hi dendritic cells (percentage of CD45+ cells) [%] DC_11b 49107

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage Siglec F+ F4/80+ macrophages (percentage of CD45+ cells) [%] MAC 49108

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage neutrophils (percentage of CD45+ cells) [%] NEUT 49109

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage eosinophils (percentage of CD45+ cells) [%] EOS 49110

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage Lin^neg CD90+ innate cells (percentage of CD45+ cells) [%] Lin_neg_90_plus 49111

inbred

5

m

7-11wks

N=6

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage Lin^neg CD90^- innate cells (percentage of CD45+ cells) [%] Lin_neg_90_neg 49112

inbred

5

m

7-11wks

N=6

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD19+ B cells (percentage of CD45+ cells) [%] B_cells 49113

inbred

5

m

7-11wks

N=8

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD3+ T cells (percentage of CD45+ cells) [%] T_CD3 49114

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD3+ CD8+ T cells (percentage of CD45+ cells) [%] T_CD8 49115

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD3+ CD4+ T cells (percentage of CD45+ cells) [%] T_CD4 49116

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD3+ CD4+ CD25+ T cells (percentage of CD45+ cells) [%] T_CD4_25 49117

inbred

5

m

7-11wks

N=8

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD3+ CD4+ CD25^hi Treg cells (percentage of CD45+ cells) [%] T_CD4_25hi 49118

inbred

5

m

7-11wks

N=5

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD3+ CD4+ CD25^hi Foxp3+ Treg cells (percentage of CD45+ cells) [%] T_CD4_foxp3 49119

inbred

5

m

7-11wks

N=5

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD3+ CD4+ CD25^hi Foxp3+ CD39+ Treg cells (percentage of CD45+ cells) [%] T_CD4_39 49120

inbred

5

m

7-11wks

N=5

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD3+ gamma-delta T cells (percentage of CD45+ cells) [%] T_gd 49121

inbred

5

m

7-11wks

N=9

2012

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD49+ natural killer (NK) cells (percentage of CD45+ cells) [%] NK 49122

inbred

5

m

7-11wks

N=9

2012

Haston1

health assessment

radiation

number of days in the absence of respiratory distress [d] survival 48801

inbred

26

both

15-36wks

N=7

2012

Haston1

histopathology

radiation

percentage of lung surface covered by fibrotic scar [%] fibrosis 48802

inbred

26

both

15-36wks

N=6

2012

Haston1

bronchoalveolar lavage assessment

radiation

percentage of macrophages in bronchoalveolar lavage [%] BAL_mac 48803

inbred

26

both

15-36wks

N=6

2012

Haston1

bronchoalveolar lavage assessment

radiation

percentage of lymphocytes in bronchoalveolar lavage [%] BAL_lym 48804

inbred

26

both

15-36wks

N=6

2012

Haston1

bronchoalveolar lavage assessment

radiation

percentage of neutrophils in bronchoalveolar lavage [%] BAL_neut 48805

inbred

26

both

15-36wks

N=6

2012

Haston1

histopathology

radiation

average number of mast cells per mm² of lung tissue [n] mast_cells 48806

inbred

25

both

15-36wks

N=6

2012

Haston1

histopathology

radiation

inflammation index (0=no alveolitis, 6=severe alveolitis) [score] alveolitis 48807

inbred

26

both

15-36wks

N=6

2012

Hunter1

histopathology

(none)

number of pulmonary metastases [n] mets 6006

MMTV PyVT transgenic

28

f

N=19

1998

Hunter1

histopathology

(none)

area of pulmonary metastases (x 10³) [µm²] met_area 6007

MMTV PyVT transgenic

28

f

N=14

1998

Hunter1

histopathology

(none)

total lung area (x 10³) [µm²] tot_area 6008

MMTV PyVT transgenic

28

f

N=14

1998

Hunter1

histopathology

(none)

number of pulmonary metastases per total lung area (x 10^-9) [n/µm²] ratio_mta 6009

MMTV PyVT transgenic

28

f

N=14

1998

Hunter1

histopathology

(none)

area of pulmonary metastases per number of metastases [µm²/n] met_size 6010

MMTV PyVT transgenic

28

f

N=14

1998

Hunter1

histopathology

(none)

area of pulmonary metastases per total lung area [ratio] ratio_ata 6011

MMTV PyVT transgenic

28

f

N=14

1998

Schughart4

in vitro assay

influenza A (H3N2) virus

viral load in lungs (titer, FFU per lung) log10 (x+1) [log(n)] titer_trt 58783 days post-infection: 3 5 8

inbred w/CC8

8

f

8-12wks

N=5

2016

Schulz1

ventilator

(none)

inspiratory capacity (+ 25 cm H₂O) [µL] IC 1606

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

functional residual capacity [µL] FRC 1607

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

total lung capacity [µL] TLC 1608

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

vital capacity [µL] VC 1609

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

dynamic compliance of respiratory system with breathing rate of 130 per min (H₂O pressure) [µL/cm] Cdyn130 1610

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

static compliance of respiratory system (H₂O pressure) [µL/cm] CRS 1611

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

static compliance of lung (H₂O pressure) [µL/cm] CL 1612

inbred

7

both

12-14wks

N=14

2000

Schulz1

ventilator

(none)

respiratory system resistance with breathing rate of 130 per min (H₂O pressure) [cm/mL/s] R 1613

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

specific respiratory system resistance with breathing rate of 130 per min related to total lung capacity (H₂O pressure) [cm⋅s] sR 1614

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

intrapulmonary gas mixing: slope of phase III (Hg pressure) [mm/mL] slope 1616

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

alveolar volume [µL] VA 1617

inbred

7

both

12-14wks

N=14

2000

Schulz1

ventilator

(none)

diffusing capacity: carbon monoxide [µmol/min/hPa] D_CO 1618

inbred

7

both

12-14wks

N=14

2000

Schulz1

ventilator

(none)

specific diffusing capacity: carbon monoxide to alveolar volume [µmol/min/hPa/mL] sD_CO 1619

inbred

7

both

12-14wks

N=14

2000

Schulz1

ventilator

(none)

functional residual capacity to total lung capacity [µL/µL] ratio_FRC_TLC 1620

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

total lung capacity to body weight [µL/g] ratio_TLC_bw 1622

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

vital capacity to body weight [L/g] ratio_VC_bw 1623

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

functional residual capacity to body weight [µL/g] ratio_FRC_bw 1624

inbred

7

both

12-14wks

N=14

2000

Schulz1

ventilator

(none)

static compliance of lung related to total lung capacity (H₂O pressure) [1/cm] ratio_CL_TLC 1626

inbred

7

both

12-14wks

N=14

2000

Schulz1

ventilator

(none)

dynamic compliance of respiratory system (breathing rate 130/min) related to total lung capacity (H₂O pressure) [1/cm] ratio_Cdyn130_TLC 1627

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

Fowler dead space volume to total lung capacity [µL/µL] ratio_VDF_TLC 1630

inbred

7

both

12-14wks

N=15

2000

Schulz1

ventilator

(none)

Fowler dead space volume to body weight [µL/g] ratio_VDF_bw 1631

inbred

7

both

12-14wks

N=14

2000

Schulz1

ventilator

(none)

Fowler dead space volume [µL] VDF 1632

inbred

7

both

12-14wks

N=15

2000

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar eosinophils (percentage of total lavage cells), pre-challenge [%] pctEOS0 9801 pre-test: control OVA-sensitized

inbred

8

m

6-8wks

N=3

2001

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar eosinophils (percentage of total lavage cells), 24h post-challenge [%] pctEOS24 9802 24h post: control OVA-sensitized

inbred

8

m

6-8wks

N=5

2001

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar eosinophils (percentage of total lavage cells), 48h post-challenge [%] pctEOS48 9803 48h post: control OVA-sensitized

inbred

8

m

6-8wks

N=5

2001

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar eosinophils (percentage of total lavage cells), 72h post-challenge [%] pctEOS72 9804 72h post: control OVA-sensitized

inbred

8

m

6-8wks

N=5

2001

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar lymphocytes (percentage of total lavage cells), pre-challenge [%] pctLYM0 9821 pre-test: control OVA-sensitized

inbred

8

m

6-8wks

N=3

2001

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar lymphocytes (percentage of total lavage cells), 24h post-challenge [%] pctLYM24 9822 24h post: control OVA-sensitized

inbred

8

m

6-8wks

N=5

2001

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar lymphocytes (percentage of total lavage cells), 48h post-challenge [%] pctLYM48 9823 48h post: control OVA-sensitized

inbred

8

m

6-8wks

N=5

2001

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar lymphocytes (percentage of total lavage cells), 72h post-challenge [%] pctLYM72 9824 72h post: control OVA-sensitized

inbred

8

m

6-8wks

N=5

2001

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar neutrophils (percentage of total lavage cells), pre-challenge [%] pctNEUT0 9841 pre-test: control OVA-sensitized

inbred

8

m

6-8wks

N=3

2001

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar neutrophils (percentage of total lavage cells), 24h post-challenge [%] pctNEUT24 9842 24h post: control OVA-sensitized

inbred

8

m

6-8wks

N=5

2001

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar neutrophils (percentage of total lavage cells), 48h post-challenge [%] pctNEUT48 9843 48h post: control OVA-sensitized

inbred

8

m

6-8wks

N=5

2001

Schwartz2

bronchoalveolar lavage assessment

ovalbumin

alveolar neutrophils (percentage of total lavage cells), 72h post-challenge [%] pctNEUT72 9844 72h post: control OVA-sensitized

inbred

8

m

6-8wks

N=5

2001

Filter Table Results