Phenotype measures set

ID, description, units MPD:35108   breath frequency   [n/min]
methacholine study
Measures • saline    • 5 MCh    • 10 MCh    • 20 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings



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Berndt2 - breath frequency

Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 3214.9198 3214.9198 1.0653 0.3026
between   strain 28 2074434.0047 74086.9287 24.5486 < 0.0001
between   sex:strain 28 132667.9225 4738.1401 1.57 0.0343
between   Residuals 412 1243403.1836 3017.9689
within   group 3 22326.8838 7442.2946 5.3752 0.0011
within   group:sex 3 4648.4695 1549.4898 1.1191 0.3402
within   group:strain 84 804371.4472 9575.8506 6.9162 < 0.0001
within   group:sex:strain 84 159844.3874 1902.9094 1.3744 0.0164
within   Residuals 1236 1711317.7946 1384.5613

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelNo.
strains
SexAge
Berndt2 35108 plethysmography methacholine breath frequency   [n/min]   saline   breath_freq_saline inbred 29 both 9-12wks
Berndt2 35109 plethysmography methacholine breath frequency   [n/min]   5 MCh   breath_freq_mch5 inbred 29 both 9-12wks
Berndt2 35110 plethysmography methacholine breath frequency   [n/min]   10 MCh   breath_freq_mch10 inbred 29 both 9-12wks
Berndt2 35111 plethysmography methacholine breath frequency   [n/min]   20 MCh   breath_freq_mch20 inbred 29 both 9-12wks
Berndt2 35112 plethysmography methacholine breath frequency   [n/min]   response index   breath_freq_slope inbred 29 both 9-12wks (not included in the analysis / display)