Phenotype measures set

ID, description, units MPD:35134   duty cycle   [ratio]
methacholine study
Measures • saline    • 5 MCh    • 10 MCh    • 20 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings



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Berndt2 - duty cycle

Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 0.097 0.097 48.184 < 0.0001
between   strain 28 1.0643 0.038 18.8839 < 0.0001
between   sex:strain 28 0.127 0.0045 2.2529 0.0003
between   Residuals 412 0.8293 0.002
within   group 3 0.8132 0.2711 343.4212 < 0.0001
within   group:sex 3 0.0108 0.0036 4.5744 0.0034
within   group:strain 84 0.5256 0.0063 7.9272 < 0.0001
within   group:sex:strain 84 0.0949 0.0011 1.4307 0.0079
within   Residuals 1236 0.9756 0.0008

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelNo.
strains
SexAge
Berndt2 35134 plethysmography methacholine duty cycle   [ratio]   saline   duty_cycle_saline inbred 29 both 9-12wks
Berndt2 35135 plethysmography methacholine duty cycle   [ratio]   5 MCh   duty_cycle_mch5 inbred 29 both 9-12wks
Berndt2 35136 plethysmography methacholine duty cycle   [ratio]   10 MCh   duty_cycle_mch10 inbred 29 both 9-12wks
Berndt2 35137 plethysmography methacholine duty cycle   [ratio]   20 MCh   duty_cycle_mch20 inbred 29 both 9-12wks
Berndt2 35138 plethysmography methacholine duty cycle   [ratio]   response index   duty_cycle_slope inbred 29 both 9-12wks (not included in the analysis / display)