Project measures / variables set:   Berndt2   insp_flow

ID, description, units MPD:35141   insp_flow   inspiratory flow rate   [mL/kg/s]  
methacholine study
Measures
• saline    • 5 MCh    • 10 MCh    • 20 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Berndt2 - inspiratory flow rate




  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 21.2361 21.2361 29.999 < 0.0001
between   strain 28 641.9374 22.9263 32.3867 < 0.0001
between   sex:strain 28 42.6536 1.5233 2.1519 0.0007
between   Residuals 412 291.6522 0.7079
within   group 3 920.3597 306.7866 916.5177 < 0.0001
within   group:sex 3 1.0958 0.3653 1.0913 0.3517
within   group:strain 84 242.6642 2.8889 8.6304 < 0.0001
within   group:sex:strain 84 42.0164 0.5002 1.4943 0.0033
within   Residuals 1236 413.7271 0.3347

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested
SexAge
Berndt2 35141 plethysmography methacholine inspiratory flow rate   [mL/kg/s]   saline  insp_flow_saline inbred 29 both 9-12wks
Berndt2 35142 plethysmography methacholine inspiratory flow rate   [mL/kg/s]   5 MCh  insp_flow_mch5 inbred 29 both 9-12wks
Berndt2 35143 plethysmography methacholine inspiratory flow rate   [mL/kg/s]   10 MCh  insp_flow_mch10 inbred 29 both 9-12wks
Berndt2 35144 plethysmography methacholine inspiratory flow rate   [mL/kg/s]   20 MCh  insp_flow_mch20 inbred 29 both 9-12wks
Berndt2 35145 plethysmography methacholine inspiratory flow rate   [mL/kg/s]   response index  insp_flow_slope inbred 29 both 9-12wks (supplemental /
  summary measure)