Phenotype measures set

ID, description, units MPD:35154   respiratory flow rate   [mL/kg/s]
methacholine study
Measures • saline    • 5 MCh    • 10 MCh    • 20 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings



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Berndt2 - respiratory flow rate

Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 5.8785 5.8785 40.6588 < 0.0001
between   strain 28 118.519 4.2328 29.2764 < 0.0001
between   sex:strain 28 7.7704 0.2775 1.9194 0.0038
between   Residuals 412 59.5675 0.1446
within   group 3 18.73 6.2433 113.4395 < 0.0001
within   group:sex 3 0.5298 0.1766 3.2086 0.0224
within   group:strain 84 40.2959 0.4797 8.7163 < 0.0001
within   group:sex:strain 84 7.0761 0.0842 1.5306 0.0019
within   Residuals 1236 68.0252 0.055

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelNo.
strains
SexAge
Berndt2 35154 plethysmography methacholine respiratory flow rate   [mL/kg/s]   saline   resp_flow_saline inbred 29 both 9-12wks
Berndt2 35155 plethysmography methacholine respiratory flow rate   [mL/kg/s]   5 MCh   resp_flow_mch5 inbred 29 both 9-12wks
Berndt2 35156 plethysmography methacholine respiratory flow rate   [mL/kg/s]   10 MCh   resp_flow_mch10 inbred 29 both 9-12wks
Berndt2 35157 plethysmography methacholine respiratory flow rate   [mL/kg/s]   20 MCh   resp_flow_mch20 inbred 29 both 9-12wks
Berndt2 35158 plethysmography methacholine respiratory flow rate   [mL/kg/s]   response index   resp_flow_slope inbred 29 both 9-12wks (not included in the analysis / display)