Project measures / variables set:   Berndt2   resp_flow

ID, description, units MPD:35154   resp_flow   respiratory flow rate   [mL/kg/s]  
methacholine study
Measures
• saline    • 5 MCh    • 10 MCh    • 20 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Berndt2 - respiratory flow rate




  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 5.8785 5.8785 40.6588 < 0.0001
between   strain 28 118.519 4.2328 29.2764 < 0.0001
between   sex:strain 28 7.7704 0.2775 1.9194 0.0038
between   Residuals 412 59.5675 0.1446
within   group 3 18.73 6.2433 113.4395 < 0.0001
within   group:sex 3 0.5298 0.1766 3.2086 0.0224
within   group:strain 84 40.2959 0.4797 8.7163 < 0.0001
within   group:sex:strain 84 7.0761 0.0842 1.5306 0.0019
within   Residuals 1236 68.0252 0.055

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested
SexAge
Berndt2 35154 plethysmography methacholine respiratory flow rate   [mL/kg/s]   saline  resp_flow_saline inbred 29 both 9-12wks
Berndt2 35155 plethysmography methacholine respiratory flow rate   [mL/kg/s]   5 MCh  resp_flow_mch5 inbred 29 both 9-12wks
Berndt2 35156 plethysmography methacholine respiratory flow rate   [mL/kg/s]   10 MCh  resp_flow_mch10 inbred 29 both 9-12wks
Berndt2 35157 plethysmography methacholine respiratory flow rate   [mL/kg/s]   20 MCh  resp_flow_mch20 inbred 29 both 9-12wks
Berndt2 35158 plethysmography methacholine respiratory flow rate   [mL/kg/s]   response index  resp_flow_slope inbred 29 both 9-12wks (supplemental /
  summary measure)