Phenotype measures set

ID, description, units MPD:35101   minute ventilation   [mL/min]
methacholine study
Measures • saline    • 5 MCh    • 10 MCh    • 20 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings



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Berndt2 - minute ventilation

Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 20056.8554 20056.8554 35.4598 < 0.0001
between   strain 28 458936.3894 16390.5853 28.978 < 0.0001
between   sex:strain 28 28150.3951 1005.3713 1.7775 0.0096
between   Residuals 412 233036.1805 565.6218
within   group 3 58535.0881 19511.696 85.3183 < 0.0001
within   group:sex 3 1632.99 544.33 2.3802 0.0681
within   group:strain 84 159307.2205 1896.5145 8.2928 < 0.0001
within   group:sex:strain 84 27681.1555 329.5376 1.441 0.0069
within   Residuals 1236 282664.4035 228.6929

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelNo.
strains
SexAge
Berndt2 35101 plethysmography methacholine minute ventilation   [mL/min]   saline   min_vent_saline inbred 29 both 9-12wks
Berndt2 35102 plethysmography methacholine minute ventilation   [mL/min]   5 MCh   min_vent_mch5 inbred 29 both 9-12wks
Berndt2 35103 plethysmography methacholine minute ventilation   [mL/min]   10 MCh   min_vent_mch10 inbred 29 both 9-12wks
Berndt2 35104 plethysmography methacholine minute ventilation   [mL/min]   20 MCh   min_vent_mch20 inbred 29 both 9-12wks
Berndt2 35105 plethysmography methacholine minute ventilation   [mL/min]   response index   min_vent_slope inbred 29 both 9-12wks (not included in the analysis / display)