Phenotype measure:   Haston1   mast_cells

ID, description, units MPD:48806   mast_cells   average number of mast cells per mm2 of lung tissue   [n]
radiation study
Data set, strains Haston1   inbred   19 strains     sex: both     age: 15-36wks
Procedure histopathology
Ontology mappings

  STRAIN COMPARISON PLOT
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Haston1 - average number of mast cells per mm2 of lung tissue



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested19 strains16 strains
Mean of the strain means44.7   n 39.9   n
Median of the strain means28.3   n 16.2   n
SD of the strain means± 66.7 ± 99.3
Coefficient of variation (CV)1.49 2.49
Min–max range of strain means4.17   –   301   n 2.20   –   410   n
Mean sample size per strain7.3   mice 5.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 275.9024 275.9024 1.4287 0.2347
strain 8 16335.5721 2041.9465 10.5735 < 0.0001
sex:strain 8 1543.135 192.8919 0.9988 0.4415
Residuals 105 20277.4556 193.1186


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.0 15.2   10 4.81 0.661 2.0, 51.0 -0.33
129S1/SvImJ m 26.6 14.9   7 5.62 0.559 7.0, 48.0 -0.13
A/J f 301.0 0.0   1   0.0 0.0 301.0, 301.0 3.85
A/J m 410.0 135.0   5 60.6 0.33 180.0, 509.0 3.73
AKR/J f 26.8 19.9   9 6.63 0.743 10.0, 74.0 -0.27
AKR/J m 7.5 6.89   6 2.81 0.919 -0.33
BTBR T+ Itpr3tf/J f 6.14 5.05   7 1.91 0.822 -0.58
BTBR T+ Itpr3tf/J m 2.33 4.32   6 1.76 1.85 -0.38
BUB/BnJ f 101.0 46.0   8 16.3 0.456 22.0, 160.0 0.84
C3H/HeJ f 28.3 10.4   10 3.3 0.369 15.0, 44.0 -0.25
C57BL/6J f 4.33 3.72   6 1.52 0.859 -0.61
C57BL/6J m 2.2 2.49   5 1.11 1.13 -0.38
C57BLKS/J m 22.4 21.5   5 9.63 0.961 5.0, 58.0 -0.18
C58/J f 58.2 21.7   9 7.22 0.372 22.0, 84.0 0.2
CBA/J m 16.6 7.64   5 3.41 0.46 8.0, 25.0 -0.23
CE/J f 29.4 22.0   8 7.79 0.75 -0.23
DBA/2J f 36.7 20.3   10 6.43 0.554 11.0, 63.0 -0.12
DBA/2J m 33.5 21.8   10 6.89 0.651 2.0, 58.0 -0.06
FVB/NJ f 24.3 18.7   9 6.25 0.77 7.0, 68.0 -0.31
FVB/NJ m 26.6 11.5   7 4.36 0.434 10.0, 44.0 -0.13
I/LnJ f 66.3 23.1   9 7.71 0.349 38.0, 119.0 0.32
KK/HlJ f 6.75 8.26   4 4.13 1.22 1.0, 19.0 -0.57
KK/HlJ m 4.4 2.41   5 1.08 0.547 1.0, 7.0 -0.36
LG/J f 16.1 7.49   10 2.37 0.465 9.0, 30.0 -0.43
LP/J m 30.3 15.3   3 8.84 0.505 13.0, 42.0 -0.1
MA/MyJ f 37.6 34.9   7 13.2 0.929 7.0, 99.0 -0.11
NOD/ShiLtJ f 4.17 3.06   6 1.25 0.735 2.0, 9.0 -0.61
NOD/ShiLtJ m 3.57 2.44   7 0.922 0.683 1.0, 7.0 -0.37
NON/ShiLtJ f 30.0 13.5   3 7.77 0.448 19.0, 45.0 -0.22
NZB/BlNJ m 3.0 1.0   3 0.577 0.333 2.0, 4.0 -0.37
NZW/LacJ f 7.25 10.9   4 5.44 1.5 -0.56
NZW/LacJ m 15.8 14.6   5 6.51 0.922 3.0, 40.0 -0.24
PL/J f 41.6 21.8   5 9.75 0.524 13.0, 65.0 -0.05
SJL/J m 20.7 24.7   3 14.2 1.19 4.0, 49.0 -0.19
SM/J m 12.4 11.3   5 5.07 0.913 -0.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.0 4.3945 31.7135 14.2865
129S1/SvImJ m 26.5714 5.2525 36.9861 16.1568
AKR/J f 26.7778 4.6322 35.9626 17.5929
AKR/J m 7.5 5.6733 18.7491 0.0
BTBR T+ Itpr3tf/J f 6.1429 5.2525 16.5575 0.0
BTBR T+ Itpr3tf/J m 2.3333 5.6733 13.5825 0.0
C57BL/6J f 4.3333 5.6733 15.5825 0.0
C57BL/6J m 2.2 6.2148 14.5228 0.0
DBA/2J f 36.7 4.3945 45.4135 27.9865
DBA/2J m 33.5 4.3945 42.2135 24.7865
FVB/NJ f 24.3333 4.6322 33.5182 15.1485
FVB/NJ m 26.5714 5.2525 36.9861 16.1568
KK/HlJ f 6.75 6.9484 20.5273 0.0
KK/HlJ m 4.4 6.2148 16.7228 0.0
NOD/ShiLtJ f 4.1667 5.6733 15.4158 0.0
NOD/ShiLtJ m 3.5714 5.2525 13.9861 0.0
NZW/LacJ f 7.25 6.9484 21.0273 0.0
NZW/LacJ m 15.8 6.2148 28.1228 3.4772


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 24.7857 3.4242 31.5752 17.9962
AKR/J both 17.1389 3.6621 24.4002 9.8776
BTBR T+ Itpr3tf/J both 4.2381 3.8657 11.9031 0.0
C57BL/6J both 3.2667 4.2074 11.6092 0.0
DBA/2J both 35.1 3.1074 41.2614 28.9386
FVB/NJ both 25.4524 3.5016 32.3955 18.5093
KK/HlJ both 5.575 4.6611 14.8171 0.0
NOD/ShiLtJ both 3.869 3.8657 11.534 0.0
NZW/LacJ both 11.525 4.6611 20.7671 2.2829




  GWAS USING LINEAR MIXED MODELS