Project measures / variables set:   Berndt2   tot_respi

ID, description, units MPD:35128   tot_respi   respiratory cycle   [s]  
methacholine study
Measures
• saline    • 5 MCh    • 10 MCh    • 20 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES


  OVERLAPPING STRAIN CURVES
Data
Dimensions px
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Berndt2 - respiratory cycle


Created with Highcharts 6.0.7measureChart context menuFemale129S1/SvImJA/JAKR/JBALB/cByJBALB/cJBTBR T+ Itpr3tf/JBUB/BnJC3H/HeJC57BL/10JC57BL/6JC57BLKS/JC57BR/cdJC57L/JCBA/JCE/JDBA/1JDBA/2JFVB/NJI/LnJKK/HlJLP/JNOD/ShiLtJNON/ShiLtJNZW/LacJPL/JRIIIS/JSJL/JSM/JSWR/Jsaline5 MCh10 MCh20 MCh0.10.20.30.40.50.60.70.8
s

Created with Highcharts 6.0.7measureChart context menuMale129S1/SvImJA/JAKR/JBALB/cByJBALB/cJBTBR T+ Itpr3tf/JBUB/BnJC3H/HeJC57BL/10JC57BL/6JC57BLKS/JC57BR/cdJC57L/JCBA/JCE/JDBA/1JDBA/2JFVB/NJI/LnJKK/HlJLP/JNOD/ShiLtJNON/ShiLtJNZW/LacJPL/JRIIIS/JSJL/JSM/JSWR/Jsaline5 MCh10 MCh20 MCh0.10.20.30.40.50.6
s


  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 0.0315 0.0315 4.2253 0.0405
between   strain 28 4.2388 0.1514 20.3021 < 0.0001
between   sex:strain 28 0.3955 0.0141 1.894 0.0045
between   Residuals 412 3.0722 0.0075
within   group 3 0.0037 0.0012 0.3783 0.7687
within   group:sex 3 0.0132 0.0044 1.3435 0.2587
within   group:strain 84 2.0953 0.0249 7.6356 < 0.0001
within   group:sex:strain 84 0.3495 0.0042 1.2738 0.0529
within   Residuals 1236 4.0377 0.0033

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested
SexAge
Berndt2 35128 plethysmography methacholine respiratory cycle   [s]   saline  tot_respi_saline inbred 29 both 9-12wks
Berndt2 35129 plethysmography methacholine respiratory cycle   [s]   5 MCh  tot_respi_mch5 inbred 29 both 9-12wks
Berndt2 35130 plethysmography methacholine respiratory cycle   [s]   10 MCh  tot_respi_mch10 inbred 29 both 9-12wks
Berndt2 35131 plethysmography methacholine respiratory cycle   [s]   20 MCh  tot_respi_mch20 inbred 29 both 9-12wks
Berndt2 35132 plethysmography methacholine respiratory cycle   [s]   response index  tot_respi_slope inbred 29 both 9-12wks (supplemental /
  summary measure)