Phenotype measures set

ID, description, units MPD:35191   lung tissue dynamic elastance (H20 pressure)   [cm/mL]
methacholine study
Measures • saline    • 1 MCh    • 3 MCh    • 10 MCh    • 30 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure ventilator
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings



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Berndt2 - lung tissue dynamic elastance (H20 pressure)

Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 33211.6552 33211.6552 70.8765 < 0.0001
between   strain 23 143627.8166 6244.6877 13.3267 < 0.0001
between   sex:strain 23 32354.1322 1406.7014 3.002 < 0.0001
between   Residuals 251 117614.8551 468.5851
within   group 4 269251.8537 67312.9634 648.1558 < 0.0001
within   group:sex 4 238.5683 59.6421 0.5743 0.6813
within   group:strain 92 31342.7553 340.6821 3.2804 < 0.0001
within   group:sex:strain 92 26692.6337 290.1373 2.7937 < 0.0001
within   Residuals 1004 104268.4689 103.8531

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelNo.
strains
SexAge
Berndt2 35191 ventilator methacholine lung tissue dynamic elastance (H20 pressure)   [cm/mL]   saline   airway_elas_saline inbred 29 both 9-12wks
Berndt2 35192 ventilator methacholine lung tissue dynamic elastance (H20 pressure)   [cm/mL]   1 MCh   airway_elas_mch1 inbred 29 both 9-12wks
Berndt2 35193 ventilator methacholine lung tissue dynamic elastance (H20 pressure)   [cm/mL]   3 MCh   airway_elas_mch3 inbred 29 both 9-12wks
Berndt2 35194 ventilator methacholine lung tissue dynamic elastance (H20 pressure)   [cm/mL]   10 MCh   airway_elas_mch10 inbred 29 both 9-12wks
Berndt2 35195 ventilator methacholine lung tissue dynamic elastance (H20 pressure)   [cm/mL]   30 MCh   airway_elas_mch30 inbred 29 both 9-12wks
Berndt2 35196 ventilator methacholine lung tissue dynamic elastance (H20 pressure)   [cm/mL]   response index   airway_elas_slope inbred 29 both 9-12wks (not included in the analysis / display)