Phenotype measures set

ID, description, units MPD:35168   tidal volume   [mL]
methacholine study
Measures • saline    • 5 MCh    • 10 MCh    • 20 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings



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Berndt2 - tidal volume

Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 0.2814 0.2814 83.4471 < 0.0001
between   strain 28 3.7211 0.1329 39.4058 < 0.0001
between   sex:strain 28 0.2447 0.0087 2.5909 < 0.0001
between   Residuals 412 1.3895 0.0034
within   group 3 1.3243 0.4414 333.277 < 0.0001
within   group:sex 3 0.0354 0.0118 8.9147 < 0.0001
within   group:strain 84 1.2483 0.0149 11.2199 < 0.0001
within   group:sex:strain 84 0.1908 0.0023 1.715 0.0001
within   Residuals 1236 1.6371 0.0013

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelNo.
strains
SexAge
Berndt2 35168 plethysmography methacholine tidal volume   [mL]   saline   tidal_vol_saline inbred 29 both 9-12wks
Berndt2 35169 plethysmography methacholine tidal volume   [mL]   5 MCh   tidal_vol_mch5 inbred 29 both 9-12wks
Berndt2 35170 plethysmography methacholine tidal volume   [mL]   10 MCh   tidal_vol_mch10 inbred 29 both 9-12wks
Berndt2 35171 plethysmography methacholine tidal volume   [mL]   20 MCh   tidal_vol_mch20 inbred 29 both 9-12wks
Berndt2 35172 plethysmography methacholine tidal volume   [mL]   response index   tidal_vol_slope inbred 29 both 9-12wks (not included in the analysis / display)