Phenotype measures set

ID, description, units MPD:35181   airway resistance (H20 pressure)   [cm/mL/s]
methacholine study
Measures • saline    • 1 MCh    • 3 MCh    • 10 MCh    • 30 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure ventilator
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings



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Berndt2 - airway resistance (H20 pressure)

Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 3.5056 3.5056 23.2561 < 0.0001
between   strain 25 43.8974 1.7559 11.6484 < 0.0001
between   sex:strain 25 16.7194 0.6688 4.4366 < 0.0001
between   Residuals 285 42.9612 0.1507
within   group 4 332.4687 83.1172 1806.5092 < 0.0001
within   group:sex 4 4.8668 1.2167 26.4443 < 0.0001
within   group:strain 100 18.9532 0.1895 4.1194 < 0.0001
within   group:sex:strain 100 8.2113 0.0821 1.7847 < 0.0001
within   Residuals 1140 52.4512 0.046

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelNo.
strains
SexAge
Berndt2 35181 ventilator methacholine airway resistance (H20 pressure)   [cm/mL/s]   saline   airway_res_saline inbred 29 both 9-12wks
Berndt2 35182 ventilator methacholine airway resistance (H20 pressure)   [cm/mL/s]   1 MCh   airway_res_mch1 inbred 29 both 9-12wks
Berndt2 35183 ventilator methacholine airway resistance (H20 pressure)   [cm/mL/s]   3 MCh   airway_res_mch3 inbred 29 both 9-12wks
Berndt2 35184 ventilator methacholine airway resistance (H20 pressure)   [cm/mL/s]   10 MCh   airway_res_mch10 inbred 29 both 9-12wks
Berndt2 35185 ventilator methacholine airway resistance (H20 pressure)   [cm/mL/s]   30 MCh   airway_res_mch30 inbred 29 both 9-12wks
Berndt2 35186 ventilator methacholine airway resistance (H20 pressure)   [cm/mL/s]   response index   airway_res_slope inbred 29 both 9-12wks (not included in the analysis / display)