Project measure / variable:   Schulz1   sD_CO

ID, description, units MPD:1619   sD_CO   specific diffusing capacity: carbon monoxide to alveolar volume   [µmol/min/hPa/mL]  
Data set, strains Schulz1   inbred   7 strains     sex: both     age: 12-14wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Schulz1 - specific diffusing capacity: carbon monoxide to alveolar volume



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means10.4   µmol/min/hPa/mL 10.5   µmol/min/hPa/mL
Median of the strain means10.4   µmol/min/hPa/mL 10.7   µmol/min/hPa/mL
SD of the strain means± 0.629 ± 0.902
Coefficient of variation (CV)0.0607 0.0861
Min–max range of strain means9.32   –   11.4   µmol/min/hPa/mL 8.72   –   11.6   µmol/min/hPa/mL
Mean sample size per strain14.6   mice 14.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.1692 1.1692 2.0707 0.1518
strain 6 88.662 14.777 26.171 < 0.0001
sex:strain 6 8.4075 1.4012 2.4817 0.0247
Residuals 188 106.151 0.5646


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.1 0.454   15 0.117 0.045 9.29, 11.0 -0.41
129S1/SvImJ m 10.8 0.535   15 0.138 0.0495 9.65, 11.9 0.36
A/J f 10.4 0.815   16 0.204 0.0785 8.12, 11.3 0.06
A/J m 10.0 0.626   14 0.167 0.0624 8.84, 10.7 -0.53
BALB/cByJ f 11.4 0.555   15 0.143 0.0487 10.4, 12.0 1.65
BALB/cByJ m 11.6 0.475   16 0.119 0.041 10.5, 12.1 1.25
C3H/HeJ f 9.32 0.754   13 0.209 0.0809 7.89, 10.9 -1.65
C3H/HeJ m 8.72 1.26   12 0.365 0.145 6.42, 10.6 -1.94
C57BL/6J f 10.2 0.452   14 0.121 0.0442 9.58, 11.0 -0.25
C57BL/6J m 10.7 0.398   12 0.115 0.0371 9.77, 11.3 0.25
FVB/NJ f 10.4 1.39   16 0.346 0.133 5.57, 11.4 0.06
FVB/NJ m 10.7 0.472   15 0.122 0.0443 9.61, 11.3 0.25
SWR/J f 10.7 0.652   13 0.181 0.0608 9.05, 11.5 0.54
SWR/J m 10.8 0.844   16 0.211 0.0784 8.13, 11.5 0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.08 0.194 10.4627 9.6973
129S1/SvImJ m 10.79 0.194 11.1727 10.4073
A/J f 10.3719 0.1879 10.7424 10.0013
A/J m 10.0336 0.2008 10.4297 9.6374
BALB/cByJ f 11.3933 0.194 11.7761 11.0106
BALB/cByJ m 11.6063 0.1879 11.9768 11.2357
C3H/HeJ f 9.3192 0.2084 9.7303 8.9081
C3H/HeJ m 8.7242 0.2169 9.1521 8.2963
C57BL/6J f 10.2364 0.2008 10.6326 9.8403
C57BL/6J m 10.7225 0.2169 11.1504 10.2946
FVB/NJ f 10.4438 0.1879 10.8143 10.0732
FVB/NJ m 10.654 0.194 11.0367 10.2713
SWR/J f 10.73 0.2084 11.1411 10.3189
SWR/J m 10.7725 0.1879 11.1431 10.4019


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 10.435 0.1372 10.7056 10.1644
A/J both 10.2027 0.1375 10.474 9.9315
BALB/cByJ both 11.4998 0.135 11.7662 11.2334
C3H/HeJ both 9.0217 0.1504 9.3184 8.725
C57BL/6J both 10.4795 0.1478 10.771 10.1879
FVB/NJ both 10.5489 0.135 10.8152 10.2825
SWR/J both 10.7513 0.1403 11.028 10.4745




  GWAS USING LINEAR MIXED MODELS