Phenotype measures set

ID, description, units MPD:35161   enhanced pause  
methacholine study
Measures • saline    • 5 MCh    • 10 MCh    • 20 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings



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Berndt2 - enhanced pause

Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 112.2538 112.2538 25.3969 < 0.0001
between   strain 28 2302.9114 82.2468 18.608 < 0.0001
between   sex:strain 28 499.6404 17.8443 4.0372 < 0.0001
between   Residuals 412 1821.0304 4.42
within   group 3 6966.5807 2322.1936 954.2126 < 0.0001
within   group:sex 3 120.9484 40.3161 16.5663 < 0.0001
within   group:strain 84 2801.7108 33.3537 13.7054 < 0.0001
within   group:sex:strain 84 777.1579 9.2519 3.8017 < 0.0001
within   Residuals 1236 3007.9579 2.4336

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelNo.
strains
SexAge
Berndt2 35161 plethysmography methacholine enhanced pause   saline   penh_saline inbred 29 both 9-12wks
Berndt2 35162 plethysmography methacholine enhanced pause   5 MCh   penh_mch5 inbred 29 both 9-12wks
Berndt2 35163 plethysmography methacholine enhanced pause   10 MCh   penh_mch10 inbred 29 both 9-12wks
Berndt2 35164 plethysmography methacholine enhanced pause   20 MCh   penh_mch20 inbred 29 both 9-12wks
Berndt2 35165 plethysmography methacholine enhanced pause   response index   penh_slope inbred 29 both 9-12wks (not included in the analysis / display)