Phenotype measure:   Bopp1   luciferase_lungs

ID, description, units MPD:36406   luciferase_lungs   percentage of parasites in lungs relative to all organs tested   [%]
Plasmodium berghei study
Data set, strains Bopp1   inbred   26 strains     sex: both     age: 8-12wks
Procedure health assessment
Ontology mappings


  STRAIN COMPARISON PLOT
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Bopp1 - percentage of parasites in lungs relative to all organs tested



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains25 strains
Mean of the strain means49.4   % 50.5   %
Median of the strain means50.8   % 49.9   %
SD of the strain means± 12.5 ± 15.5
Coefficient of variation (CV)0.252 0.307
Min–max range of strain means21.6   –   72.8   % 17.1   –   84.0   %
Mean sample size per strain1.9   mice 1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.8968 0.8968 0.0076 0.9313
strain 13 9633.6156 741.0474 6.2402 < 0.0001
sex:strain 13 2391.0009 183.9231 1.5488 0.1536
Residuals 32 3800.1223 118.7538


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 35.8 3.7   2   2.61 0.103 33.2, 38.4 -1.09
129S1/SvImJ m 56.2 9.66   2   6.83 0.172 49.4, 63.0 0.37
A/J f 70.1 2.5   2   1.76 0.0356 68.3, 71.8 1.66
A/J m 50.5 17.9   2   12.7 0.355 37.8, 63.2 0.0
AKR/J f 46.3 12.1   4 6.06 0.262 30.4, 59.0 -0.25
AKR/J m 39.5 1.77   3 1.02 0.0448 37.5, 40.8 -0.71
BTBR T+ Itpr3tf/J f 72.8 13.5   2   9.53 0.185 63.3, 82.3 1.88
BTBR T+ Itpr3tf/J m 70.4 2.86   2   2.03 0.0407 68.3, 72.4 1.28
BUB/BnJ f 61.7 1.99   2   1.41 0.0323 60.3, 63.1 0.98
BUB/BnJ m 62.2 5.33   2   3.77 0.0856 58.5, 66.0 0.76
C3H/HeJ f 44.5 1.75   2   1.24 0.0394 43.3, 45.8 -0.4
C3H/HeJ m 44.7 9.8   2   6.93 0.219 37.8, 51.6 -0.37
C57BL/6J m 36.5 12.3   2   8.66 0.335 27.9, 45.2 -0.9
C57BR/cdJ f 51.5 3.99   2   2.82 0.0774 48.7, 54.4 0.17
C57BR/cdJ m 73.2 11.9   2   8.44 0.163 64.8, 81.6 1.46
C58/J f 42.1 11.7   2   8.27 0.278 33.9, 50.4 -0.59
C58/J m 35.4 22.1   2   15.6 0.625 19.8, 51.0 -0.97
CBA/J f 60.1 0.0   1   0.0 0.0 60.1, 60.1 0.86
CBA/J m 76.0 6.61   2   4.68 0.087 71.3, 80.6 1.64
CZECHII/EiJ f 45.0 0.0   1   0.0 0.0 45.0, 45.0 -0.36
CZECHII/EiJ m 48.1 0.488   2   0.345 0.0101 47.8, 48.5 -0.15
DBA/2J f 62.5 8.15   3 4.71 0.131 54.0, 70.2 1.05
DBA/2J m 84.0 0.0   1   0.0 0.0 84.0, 84.0 2.16
I/LnJ f 27.9 0.488   2   0.345 0.0175 27.6, 28.3 -1.73
I/LnJ m 39.7 0.0   1   0.0 0.0 39.7, 39.7 -0.69
KK/HlJ f 34.4 13.0   2   9.16 0.377 25.2, 43.5 -1.21
KK/HlJ m 52.2 4.69   2   3.31 0.0898 48.9, 55.5 0.11
LG/J f 53.9 16.5   2   11.7 0.307 42.2, 65.5 0.36
MRL/MpJ f 53.7 7.76   2   5.49 0.145 48.2, 59.2 0.34
NOD/ShiLtJ f 56.4 6.27   3 3.62 0.111 50.7, 63.1 0.56
NOD/ShiLtJ m 68.6 5.36   2   3.79 0.0781 64.8, 72.4 1.17
NON/ShiLtJ f 40.5 0.0   1   0.0 0.0 40.5, 40.5 -0.72
NON/ShiLtJ m 43.9 7.16   2   5.06 0.163 38.9, 49.0 -0.42
NZO/HlLtJ f 21.6 5.0   2   3.54 0.231 18.1, 25.2 -2.23
NZO/HlLtJ m 17.1 14.2   2   10.0 0.829 7.09, 27.2 -2.15
NZW/LacJ f 53.3 0.0   1   0.0 0.0 53.3, 53.3 0.31
NZW/LacJ m 52.1 0.0   1   0.0 0.0 52.1, 52.1 0.1
PERA/EiJ f 50.4 3.73   2   2.63 0.074 47.7, 53.0 0.08
P/J f 61.6 15.2   2   10.8 0.247 50.9, 72.4 0.98
P/J m 49.9 0.0   1   0.0 0.0 49.9, 49.9 -0.04
PL/J f 62.5 3.54   2   2.5 0.0567 60.0, 65.0 1.05
PL/J m 52.5 9.02   2   6.38 0.172 46.1, 58.9 0.13
RIIIS/J m 56.2 16.8   2   11.9 0.299 44.3, 68.0 0.37
SJL/J f 39.4 8.96   2   6.34 0.228 33.0, 45.7 -0.8
SJL/J m 35.5 0.0   1   0.0 0.0 35.5, 35.5 -0.97
SM/J f 51.2 4.77   2   3.38 0.0933 47.8, 54.5 0.14
SM/J m 31.8 2.45   2   1.73 0.0768 30.1, 33.6 -1.2
SWR/J f 46.3 31.8   2   22.5 0.688 23.8, 68.8 -0.25
SWR/J m 44.3 12.4   2   8.75 0.28 35.5, 53.0 -0.4
WSB/EiJ f 39.6 0.0   1   0.0 0.0 39.6, 39.6 -0.79
WSB/EiJ m 41.4 5.87   3 3.39 0.142 36.6, 47.9 -0.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 35.805 7.7056 51.5009 20.1091
129S1/SvImJ m 56.2 7.7056 71.8959 40.5041
A/J f 70.085 7.7056 85.7809 54.3891
A/J m 50.5 7.7056 66.1959 34.8041
AKR/J f 46.3025 5.4487 57.4012 35.2038
AKR/J m 39.4933 6.2916 52.309 26.6777
BTBR T+ Itpr3tf/J f 72.81 7.7056 88.5059 57.1141
BTBR T+ Itpr3tf/J m 70.365 7.7056 86.0609 54.6691
BUB/BnJ f 61.7 7.7056 77.3959 46.0041
BUB/BnJ m 62.25 7.7056 77.9459 46.5541
C3H/HeJ f 44.53 7.7056 60.2259 28.8341
C3H/HeJ m 44.71 7.7056 60.4059 29.0141
C57BR/cdJ f 51.55 7.7056 67.2459 35.8541
C57BR/cdJ m 73.195 7.7056 88.8909 57.4991
C58/J f 42.12 7.7056 57.8159 26.4241
C58/J m 35.4 7.7056 51.0959 19.7041
KK/HlJ f 34.38 7.7056 50.0759 18.6841
KK/HlJ m 52.195 7.7056 67.8909 36.4991
NOD/ShiLtJ f 56.4467 6.2916 69.2623 43.631
NOD/ShiLtJ m 68.63 7.7056 84.3259 52.9341
NZO/HlLtJ f 21.625 7.7056 37.3209 5.9291
NZO/HlLtJ m 17.13 7.7056 32.8259 1.4341
PL/J f 62.475 7.7056 78.1709 46.7791
PL/J m 52.53 7.7056 68.2259 36.8341
SM/J f 51.165 7.7056 66.8609 35.4691
SM/J m 31.84 7.7056 47.5359 16.1441
SWR/J f 46.265 7.7056 61.9609 30.5691
SWR/J m 44.26 7.7056 59.9559 28.5641


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 46.0025 5.4487 57.1012 34.9038
A/J both 60.2925 5.4487 71.3912 49.1938
AKR/J both 42.8979 4.1615 51.3747 34.4212
BTBR T+ Itpr3tf/J both 71.5875 5.4487 82.6862 60.4888
BUB/BnJ both 61.975 5.4487 73.0737 50.8763
C3H/HeJ both 44.62 5.4487 55.7187 33.5213
C57BR/cdJ both 62.3725 5.4487 73.4712 51.2738
C58/J both 38.76 5.4487 49.8587 27.6613
KK/HlJ both 43.2875 5.4487 54.3862 32.1888
NOD/ShiLtJ both 62.5383 4.974 72.67 52.4067
NZO/HlLtJ both 19.3775 5.4487 30.4762 8.2788
PL/J both 57.5025 5.4487 68.6012 46.4038
SM/J both 41.5025 5.4487 52.6012 30.4038
SWR/J both 45.2625 5.4487 56.3612 34.1638




  GENOME-WIDE ASSOCIATION (GWAS) VIEW
Plot generated with pyLMM using 132K SNP array. Click on plot to view at larger size.