Project measure / variable:   Haston1   alveolitis

ID, description, units MPD:48807   alveolitis   inflammation index (0=no alveolitis, 6=severe alveolitis)   [score]  
radiation study
Data set, strains Haston1   inbred   26 strains     sex: both     age: 15-36wks
Procedure histopathology
Ontology mappings

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  STRAIN COMPARISON PLOT
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Haston1 - inflammation index (0=no alveolitis, 6=severe alveolitis)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested20 strains16 strains
Mean of the strain means4.15   score 3.74   score
Median of the strain means4.11   score 3.85   score
SD of the strain means± 0.448 ± 0.638
Coefficient of variation (CV)0.108 0.171
Min–max range of strain means3.33   –   5.06   score 2.71   –   4.79   score
Mean sample size per strain7.3   mice 5.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.4363 3.4363 6.4299 0.0125
strain 9 34.8281 3.8698 7.2411 < 0.0001
sex:strain 9 8.7904 0.9767 1.8276 0.0701
Residuals 118 63.0617 0.5344


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.1 0.658   10 0.208 0.161 3.0, 5.0 -0.12
129S1/SvImJ m 4.0 0.764   7 0.289 0.191 3.0, 5.0 0.41
A/J f 4.0 0.816   4 0.408 0.204 3.0, 5.0 -0.34
A/J m 4.58 0.492   6 0.201 0.107 4.0, 5.0 1.32
AKR/J f 4.11 0.546   9 0.182 0.133 3.5, 5.0 -0.09
AKR/J m 3.58 0.585   6 0.239 0.163 3.0, 4.5 -0.25
BALB/cJ f 4.0 0.354   5 0.158 0.0884 3.5, 4.5 -0.34
BTBR T+ Itpr3tf/J f 4.14 0.945   7 0.357 0.228 3.0, 5.0 -0.03
BTBR T+ Itpr3tf/J m 2.71 1.07   7 0.406 0.396 1.0, 4.0 -1.61
BUB/BnJ f 5.06 0.678   8 0.24 0.134 4.0, 6.0 2.03
C3H/HeJ f 4.55 0.896   10 0.283 0.197 3.5, 6.0 0.89
C57BL/6J f 3.43 0.535   7 0.202 0.156 3.0, 4.0 -1.61
C57BL/6J m 3.14 1.35   7 0.508 0.428 1.5, 5.0 -0.94
C57BLKS/J m 3.7 0.447   5 0.2 0.121 3.0, 4.0 -0.06
C58/J f 4.33 0.5   9 0.167 0.115 3.5, 5.0 0.4
CBA/J m 3.5 0.354   5 0.158 0.101 3.0, 4.0 -0.38
CE/J f 3.94 0.904   8 0.32 0.23 2.5, 5.0 -0.47
DBA/2J f 4.8 0.537   10 0.17 0.112 4.0, 6.0 1.45
DBA/2J m 4.15 0.883   10 0.279 0.213 3.0, 6.0 0.64
FVB/NJ f 4.53 0.444   9 0.148 0.098 4.0, 5.0 0.84
FVB/NJ m 4.79 0.267   7 0.101 0.0558 4.5, 5.0 1.64
I/LnJ f 3.61 0.741   9 0.247 0.205 2.0, 4.5 -1.21
KK/HlJ f 4.25 0.957   4 0.479 0.225 3.0, 5.0 0.22
KK/HlJ m 4.25 1.13   6 0.461 0.266 3.0, 6.0 0.8
LG/J f 4.05 0.599   10 0.189 0.148 3.5, 5.0 -0.23
LP/J m 2.83 1.04   3 0.601 0.367 2.0, 4.0 -1.43
MA/MyJ f 4.36 0.748   7 0.283 0.172 3.0, 5.0 0.46
NOD/ShiLtJ f 3.33 0.408   6 0.167 0.122 3.0, 4.0 -1.84
NOD/ShiLtJ m 3.14 0.244   7 0.0922 0.0776 3.0, 3.5 -0.94
NON/ShiLtJ f 4.0 0.0   3 0.0 0.0 4.0, 4.0 -0.34
NZB/BlNJ m 4.17 0.289   3 0.167 0.0693 4.0, 4.5 0.67
NZW/LacJ f 4.75 0.5   4 0.25 0.105 4.0, 5.0 1.34
NZW/LacJ m 4.3 0.447   5 0.2 0.104 4.0, 5.0 0.88
PL/J f 3.7 0.447   5 0.2 0.121 3.0, 4.0 -1.01
SJL/J m 3.0 1.0   3 0.577 0.333 2.0, 4.0 -1.16
SM/J m 4.0 0.612   5 0.274 0.153 3.5, 5.0 0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.1 0.2312 4.5578 3.6422
129S1/SvImJ m 4.0 0.2763 4.5472 3.4528
A/J f 4.0 0.3655 4.7238 3.2762
A/J m 4.5833 0.2984 5.1743 3.9923
AKR/J f 4.1111 0.2437 4.5937 3.6286
AKR/J m 3.5833 0.2984 4.1743 2.9923
BTBR T+ Itpr3tf/J f 4.1429 0.2763 4.69 3.5957
BTBR T+ Itpr3tf/J m 2.7143 0.2763 3.2615 2.1671
C57BL/6J f 3.4286 0.2763 3.9757 2.8814
C57BL/6J m 3.1429 0.2763 3.69 2.5957
DBA/2J f 4.8 0.2312 5.2578 4.3422
DBA/2J m 4.15 0.2312 4.6078 3.6922
FVB/NJ f 4.5333 0.2437 5.0159 4.0508
FVB/NJ m 4.7857 0.2763 5.3329 4.2385
KK/HlJ f 4.25 0.3655 4.9738 3.5262
KK/HlJ m 4.25 0.2984 4.841 3.659
NOD/ShiLtJ f 3.3333 0.2984 3.9243 2.7423
NOD/ShiLtJ m 3.1429 0.2763 3.69 2.5957
NZW/LacJ f 4.75 0.3655 5.4738 4.0262
NZW/LacJ m 4.3 0.3269 4.9474 3.6526


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.05 0.1801 4.4067 3.6933
A/J both 4.2917 0.2359 4.7589 3.8244
AKR/J both 3.8472 0.1926 4.2287 3.4657
BTBR T+ Itpr3tf/J both 3.4286 0.1954 3.8155 3.0417
C57BL/6J both 3.2857 0.1954 3.6726 2.8988
DBA/2J both 4.475 0.1635 4.7987 4.1513
FVB/NJ both 4.6595 0.1842 5.0243 4.2947
KK/HlJ both 4.25 0.2359 4.7172 3.7828
NOD/ShiLtJ both 3.2381 0.2034 3.6408 2.8354
NZW/LacJ both 4.525 0.2452 5.0106 4.0394




  GWAS USING LINEAR MIXED MODELS