Project measure / variable:   Schulz1   CL

ID, description, units MPD:1612   CL   static compliance of lung (H2O pressure)   [µL/cm]  
Data set, strains Schulz1   inbred   7 strains     sex: both     age: 12-14wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Schulz1 - static compliance of lung (H2O pressure)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means72.0   µL/cm 83.9   µL/cm
Median of the strain means65.5   µL/cm 77.5   µL/cm
SD of the strain means± 14.2 ± 24.9
Coefficient of variation (CV)0.197 0.296
Min–max range of strain means54.9   –   89.1   µL/cm 62.0   –   130   µL/cm
Mean sample size per strain14.1   mice 14.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7590.4976 7590.4976 18.5735 < 0.0001
strain 6 60800.9857 10133.4976 24.796 < 0.0001
sex:strain 6 8819.3992 1469.8999 3.5968 0.0021
Residuals 183 74787.3363 408.674


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 58.4 6.41   13 1.78 0.11 49.8, 69.8 -0.96
129S1/SvImJ m 62.0 5.31   13 1.47 0.0856 49.9, 70.0 -0.88
A/J f 89.1 11.8   16 2.95 0.132 72.7, 114.0 1.21
A/J m 130.0 63.0   15 16.3 0.484 81.5, 326.0 1.85
BALB/cByJ f 86.6 10.8   13 3.0 0.125 74.5, 112.0 1.03
BALB/cByJ m 89.7 10.3   16 2.58 0.115 73.1, 108.0 0.23
C3H/HeJ f 83.7 12.0   12 3.45 0.143 71.7, 111.0 0.83
C3H/HeJ m 99.8 26.1   11 7.87 0.262 71.2, 149.0 0.64
C57BL/6J f 54.9 7.41   14 1.98 0.135 42.8, 67.2 -1.2
C57BL/6J m 62.9 7.04   12 2.03 0.112 53.9, 77.1 -0.85
FVB/NJ f 65.5 7.08   16 1.77 0.108 56.2, 84.2 -0.46
FVB/NJ m 77.5 6.0   15 1.55 0.0774 68.6, 92.4 -0.26
SWR/J f 65.5 12.2   15 3.15 0.186 53.4, 97.5 -0.46
SWR/J m 65.6 4.79   16 1.2 0.073 60.2, 79.8 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 58.3846 5.6068 69.4469 47.3223
129S1/SvImJ m 62.0385 5.6068 73.1008 50.9761
A/J f 89.0625 5.0539 99.0339 79.0911
A/J m 130.0533 5.2197 140.3518 119.7549
BALB/cByJ f 86.6154 5.6068 97.6777 75.5531
BALB/cByJ m 89.6625 5.0539 99.6339 79.6911
C3H/HeJ f 83.6917 5.8358 95.2057 72.1776
C3H/HeJ m 99.8273 6.0953 111.8533 87.8013
C57BL/6J f 54.8786 5.4029 65.5385 44.2186
C57BL/6J m 62.95 5.8358 74.464 51.436
FVB/NJ f 65.5062 5.0539 75.4777 55.5348
FVB/NJ m 77.5 5.2197 87.7985 67.2015
SWR/J f 65.46 5.2197 75.7585 55.1615
SWR/J m 65.5937 5.0539 75.5652 55.6223


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 60.2115 3.9646 68.0338 52.3893
A/J both 109.5579 3.6327 116.7253 102.3905
BALB/cByJ both 88.1389 3.7742 95.5855 80.6924
C3H/HeJ both 91.7595 4.2193 100.0841 83.4348
C57BL/6J both 58.9143 3.9764 66.7598 51.0688
FVB/NJ both 71.5031 3.6327 78.6706 64.3357
SWR/J both 65.5269 3.6327 72.6943 58.3594




  GWAS USING LINEAR MIXED MODELS