Project measure / variable:   Schulz1   ratio_VC_bw

ID, description, units MPD:1623   ratio_VC_bw   vital capacity to body weight   [L/g]  
Data set, strains Schulz1   inbred   7 strains     sex: both     age: 12-14wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Schulz1 - vital capacity to body weight



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means48.6   L/g 43.7   L/g
Median of the strain means47.7   L/g 43.4   L/g
SD of the strain means± 2.87 ± 5.44
Coefficient of variation (CV)0.0591 0.124
Min–max range of strain means44.6   –   53.9   L/g 37.4   –   53.2   L/g
Mean sample size per strain14.9   mice 14.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1149.854 1149.854 58.5386 < 0.0001
strain 6 2713.2444 452.2074 23.0217 < 0.0001
sex:strain 6 422.3989 70.3998 3.584 0.0022
Residuals 192 3771.391 19.6427


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 50.2 5.26   15 1.36 0.105 36.8, 59.8 0.55
129S1/SvImJ m 43.9 3.28   16 0.821 0.0749 38.2, 50.9 0.03
A/J f 48.7 4.23   16 1.06 0.0869 41.6, 58.1 0.03
A/J m 47.8 3.85   14 1.03 0.0805 41.0, 56.3 0.75
BALB/cByJ f 47.7 2.89   15 0.747 0.0606 44.1, 53.2 -0.32
BALB/cByJ m 43.4 1.66   16 0.416 0.0383 40.2, 45.5 -0.06
C3H/HeJ f 53.9 5.79   13 1.61 0.107 46.6, 65.4 1.84
C3H/HeJ m 53.2 9.12   14 2.44 0.171 43.1, 72.0 1.74
C57BL/6J f 47.7 3.05   14 0.814 0.0638 40.7, 52.2 -0.32
C57BL/6J m 38.5 2.65   13 0.736 0.0689 34.6, 42.8 -0.96
FVB/NJ f 44.6 6.01   16 1.5 0.135 34.2, 60.3 -1.4
FVB/NJ m 37.4 4.04   13 1.12 0.108 26.9, 41.7 -1.16
SWR/J f 47.5 2.22   15 0.573 0.0467 45.2, 52.1 -0.39
SWR/J m 41.8 2.71   16 0.677 0.0648 37.8, 48.9 -0.35


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 50.2267 1.1443 52.4838 47.9696
129S1/SvImJ m 43.85 1.108 46.0354 41.6646
A/J f 48.7 1.108 50.8854 46.5146
A/J m 47.75 1.1845 50.0863 45.4137
BALB/cByJ f 47.7467 1.1443 50.0038 45.4896
BALB/cByJ m 43.425 1.108 45.6104 41.2396
C3H/HeJ f 53.9462 1.2292 56.3707 51.5217
C3H/HeJ m 53.2429 1.1845 55.5792 50.9065
C57BL/6J f 47.6929 1.1845 50.0292 45.3565
C57BL/6J m 38.5308 1.2292 40.9553 36.1063
FVB/NJ f 44.6313 1.108 46.8167 42.4458
FVB/NJ m 37.3692 1.2292 39.7937 34.9447
SWR/J f 47.5067 1.1443 49.7638 45.2496
SWR/J m 41.7813 1.108 43.9667 39.5958


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 47.0383 0.7964 48.6092 45.4675
A/J both 48.225 0.811 49.8246 46.6254
BALB/cByJ both 45.5858 0.7964 47.1567 44.015
C3H/HeJ both 53.5945 0.8535 55.278 51.911
C57BL/6J both 43.1118 0.8535 44.7953 41.4283
FVB/NJ both 41.0002 0.8274 42.6323 39.3682
SWR/J both 44.644 0.7964 46.2148 43.0731




  GWAS USING LINEAR MIXED MODELS