Project measure / variable:   Schulz1   CRS

ID, description, units MPD:1611   CRS   static compliance of respiratory system (H2O pressure)   [µL/cm]  
Data set, strains Schulz1   inbred   7 strains     sex: both     age: 12-14wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Schulz1 - static compliance of respiratory system (H2O pressure)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means56.9   µL/cm 64.3   µL/cm
Median of the strain means54.7   µL/cm 63.1   µL/cm
SD of the strain means± 9.20 ± 13.0
Coefficient of variation (CV)0.162 0.203
Min–max range of strain means42.4   –   66.8   µL/cm 49.2   –   86.2   µL/cm
Mean sample size per strain15.0   mice 15.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3060.5852 3060.5852 56.5509 < 0.0001
strain 6 20322.132 3387.022 62.5826 < 0.0001
sex:strain 6 1879.3 313.2167 5.7874 < 0.0001
Residuals 196 10607.6876 54.1209


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 51.1 4.94   15 1.27 0.0967 42.7, 63.8 -0.63
129S1/SvImJ m 52.8 3.77   16 0.943 0.0714 41.4, 57.6 -0.88
A/J f 64.6 6.02   16 1.5 0.0932 56.2, 75.7 0.84
A/J m 74.5 5.48   15 1.41 0.0735 65.8, 85.7 0.78
BALB/cByJ f 66.8 3.7   15 0.954 0.0553 60.9, 74.7 1.08
BALB/cByJ m 68.0 4.36   16 1.09 0.0641 61.4, 76.8 0.28
C3H/HeJ f 66.0 5.6   14 1.5 0.0849 58.5, 77.8 0.99
C3H/HeJ m 86.2 22.4   15 5.77 0.259 59.8, 126.0 1.68
C57BL/6J f 42.4 3.25   14 0.868 0.0765 36.9, 48.0 -1.57
C57BL/6J m 49.2 3.25   12 0.938 0.0661 43.9, 54.6 -1.16
FVB/NJ f 54.7 5.1   16 1.27 0.0932 49.1, 71.3 -0.24
FVB/NJ m 63.1 4.56   15 1.18 0.0722 55.0, 70.5 -0.09
SWR/J f 52.5 3.81   15 0.984 0.0726 46.0, 58.8 -0.47
SWR/J m 56.5 2.14   16 0.536 0.038 53.4, 60.3 -0.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 51.06 1.8995 54.8061 47.3139
129S1/SvImJ m 52.8312 1.8392 56.4584 49.2041
A/J f 64.575 1.8392 68.2021 60.9479
A/J m 74.4533 1.8995 78.1994 70.7073
BALB/cByJ f 66.84 1.8995 70.5861 63.0939
BALB/cByJ m 68.0 1.8392 71.6271 64.3729
C3H/HeJ f 66.0214 1.9662 69.899 62.1439
C3H/HeJ m 86.2 1.8995 89.9461 82.4539
C57BL/6J f 42.4143 1.9662 46.2918 38.5367
C57BL/6J m 49.1917 2.1237 53.3799 45.0034
FVB/NJ f 54.6562 1.8392 58.2834 51.0291
FVB/NJ m 63.1133 1.8995 66.8594 59.3673
SWR/J f 52.5133 1.8995 56.2594 48.7673
SWR/J m 56.475 1.8392 60.1021 52.8479


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 51.9456 1.322 54.5528 49.3385
A/J both 69.5142 1.322 72.1213 66.907
BALB/cByJ both 67.42 1.322 70.0271 64.8129
C3H/HeJ both 76.1107 1.3669 78.8065 73.415
C57BL/6J both 45.803 1.4471 48.6568 42.9492
FVB/NJ both 58.8848 1.322 61.4919 56.2776
SWR/J both 54.4942 1.322 57.1013 51.887




  GWAS USING LINEAR MIXED MODELS