Project measure / variable:   Schulz1   sR

ID, description, units MPD:1614   sR   specific respiratory system resistance with breathing rate of 130 per min related to total lung capacity (H2O pressure)   [cm⋅s]  
Data set, strains Schulz1   inbred   7 strains     sex: both     age: 12-14wks
Procedure ventilator
Ontology mappings

  STRAIN COMPARISON PLOT
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Schulz1 - specific respiratory system resistance with breathing rate of 130 per min related to total lung capacity (H2O pressure)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means1.05   cm⋅s 1.27   cm⋅s
Median of the strain means1.14   cm⋅s 1.16   cm⋅s
SD of the strain means± 0.139 ± 0.390
Coefficient of variation (CV)0.133 0.307
Min–max range of strain means0.891   –   1.20   cm⋅s 0.914   –   2.09   cm⋅s
Mean sample size per strain14.6   mice 14.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.4545 2.4545 22.1359 < 0.0001
strain 6 10.3382 1.723 15.5394 < 0.0001
sex:strain 6 4.3857 0.731 6.5922 < 0.0001
Residuals 191 21.1784 0.1109


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.14 0.255   15 0.0658 0.224 0.779, 1.74 0.65
129S1/SvImJ m 1.33 0.355   16 0.0888 0.266 0.802, 2.1 0.15
A/J f 1.2 0.356   16 0.089 0.297 0.817, 2.16 1.08
A/J m 1.16 0.268   14 0.0715 0.231 0.773, 1.86 -0.28
BALB/cByJ f 1.15 0.193   15 0.0497 0.168 0.721, 1.51 0.72
BALB/cByJ m 1.3 0.338   16 0.0845 0.259 0.889, 2.18 0.08
C3H/HeJ f 1.15 0.327   13 0.0908 0.284 0.863, 2.03 0.72
C3H/HeJ m 2.09 0.754   14 0.201 0.36 1.06, 3.46 2.1
C57BL/6J f 0.903 0.167   14 0.0445 0.184 0.694, 1.19 -1.05
C57BL/6J m 1.02 0.137   12 0.0395 0.134 0.844, 1.3 -0.64
FVB/NJ f 0.913 0.18   16 0.0451 0.198 0.69, 1.32 -0.98
FVB/NJ m 1.08 0.326   15 0.0842 0.301 0.669, 1.81 -0.49
SWR/J f 0.891 0.272   13 0.0755 0.305 0.508, 1.34 -1.14
SWR/J m 0.914 0.283   16 0.0708 0.31 0.632, 1.82 -0.91


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.1387 0.086 1.3083 0.9691
129S1/SvImJ m 1.335 0.0832 1.4992 1.1708
A/J f 1.1978 0.0832 1.362 1.0335
A/J m 1.1596 0.089 1.3351 0.984
BALB/cByJ f 1.1482 0.086 1.3178 0.9786
BALB/cByJ m 1.3033 0.0832 1.4675 1.139
C3H/HeJ f 1.1542 0.0924 1.3363 0.972
C3H/HeJ m 2.0936 0.089 2.2691 1.918
C57BL/6J f 0.9031 0.089 1.0786 0.7275
C57BL/6J m 1.0232 0.0961 1.2129 0.8336
FVB/NJ f 0.9127 0.0832 1.077 0.7485
FVB/NJ m 1.0828 0.086 1.2524 0.9132
SWR/J f 0.8911 0.0924 1.0732 0.7089
SWR/J m 0.9137 0.0832 1.0779 0.7495


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.2369 0.0598 1.3549 1.1188
A/J both 1.1787 0.0609 1.2988 1.0585
BALB/cByJ both 1.2257 0.0598 1.3438 1.1077
C3H/HeJ both 1.6239 0.0641 1.7504 1.4974
C57BL/6J both 0.9632 0.0655 1.0924 0.834
FVB/NJ both 0.9978 0.0598 1.1158 0.8797
SWR/J both 0.9024 0.0622 1.025 0.7798




  GWAS USING LINEAR MIXED MODELS