MPD: Project measures / variables set: Schwartz2 pctEOS48

Project measures / variables set: Schwartz2 pctEOS48

ID, description, units	MPD:9803 pctEOS48 alveolar eosinophils (percentage of total lavage cells), 48h post-challenge [%] ovalbumin study
Measures	• 48h post: • control • OVA-sensitized
Data set, strains	Schwartz2 inbred 8 strains sex: m age: 6-8wks
Procedure	bronchoalveolar lavage assessment
Comparison	control group vs. treated group
Ontology mappings	VT:0001790 immune system physiology trait VT:0008723 eosinophil recruitment trait VT:0010487 response to xenobiotic stimulus trait MA:0000415 lung MP:0008872 abnormal physiological response to xenobiotic MP:0002465 abnormal eosinophil physiology

Values Means Δ Means Z-scores

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Schwartz2 - alveolar eosinophils (percentage of total lavage cells), 48h post-challenge

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	22866.1571	22866.1571	124.5692	< 0.0001
strain	7	8664.842	1237.8346	6.7434	< 0.0001
group:strain	7	9932.2179	1418.8883	7.7298	< 0.0001
Residuals	62	11380.8375	183.5619

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Schwartz2	9803	bronchoalveolar lavage assessment	ovalbumin	alveolar eosinophils (percentage of total lavage cells), 48h post-challenge [%] control pctEOS_ctrl48	inbred	8	m	6-8wks
Schwartz2	9808	bronchoalveolar lavage assessment	ovalbumin	alveolar eosinophils (percentage of total lavage cells), 48h post-challenge [%] OVA-sensitized pctEOS_ova48	inbred	8	m	6-8wks