Project measure / variable:   Schulz1   ratio_VDF_TLC

ID, description, units MPD:1630   ratio_VDF_TLC   Fowler dead space volume to total lung capacity   [µL/µL]  
Data set, strains Schulz1   inbred   7 strains     sex: both     age: 12-14wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Schulz1 - Fowler dead space volume to total lung capacity



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means0.183   µL/µL 0.166   µL/µL
Median of the strain means0.185   µL/µL 0.169   µL/µL
SD of the strain means± 0.0177 ± 0.0187
Coefficient of variation (CV)0.0969 0.113
Min–max range of strain means0.158   –   0.205   µL/µL 0.136   –   0.194   µL/µL
Mean sample size per strain14.6   mice 14.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.015 0.015 97.2211 < 0.0001
strain 6 0.0556 0.0093 59.9937 < 0.0001
sex:strain 6 0.0021 0.0004 2.2738 0.0383
Residuals 190 0.0294 0.0002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.18 0.0103   15 0.00265 0.057 0.161, 0.202 -0.17
129S1/SvImJ m 0.172 0.00764   15 0.00197 0.0445 0.157, 0.181 0.33
A/J f 0.185 0.014   16 0.00349 0.0753 0.164, 0.215 0.11
A/J m 0.169 0.0152   14 0.00405 0.09 0.149, 0.209 0.17
BALB/cByJ f 0.162 0.00478   15 0.00123 0.0295 0.153, 0.17 -1.18
BALB/cByJ m 0.149 0.00908   16 0.00227 0.0609 0.132, 0.165 -0.9
C3H/HeJ f 0.158 0.0121   13 0.00336 0.0766 0.136, 0.176 -1.41
C3H/HeJ m 0.136 0.0188   14 0.00502 0.138 0.107, 0.163 -1.6
C57BL/6J f 0.193 0.0108   14 0.00288 0.0557 0.178, 0.212 0.56
C57BL/6J m 0.166 0.0125   12 0.0036 0.075 0.153, 0.194 0.01
FVB/NJ f 0.198 0.012   16 0.003 0.0604 0.164, 0.215 0.85
FVB/NJ m 0.175 0.0186   15 0.00481 0.106 0.16, 0.238 0.49
SWR/J f 0.205 0.0116   13 0.00322 0.0566 0.189, 0.227 1.24
SWR/J m 0.194 0.00972   16 0.00243 0.0502 0.165, 0.207 1.5


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.1799 0.0032 0.1863 0.1736
129S1/SvImJ m 0.1719 0.0032 0.1782 0.1655
A/J f 0.1854 0.0031 0.1916 0.1793
A/J m 0.1685 0.0033 0.1751 0.1619
BALB/cByJ f 0.162 0.0032 0.1683 0.1557
BALB/cByJ m 0.149 0.0031 0.1551 0.1429
C3H/HeJ f 0.1583 0.0034 0.1651 0.1515
C3H/HeJ m 0.1358 0.0033 0.1423 0.1292
C57BL/6J f 0.1934 0.0033 0.1999 0.1868
C57BL/6J m 0.1662 0.0036 0.1733 0.1592
FVB/NJ f 0.1984 0.0031 0.2045 0.1922
FVB/NJ m 0.1754 0.0032 0.1817 0.1691
SWR/J f 0.2048 0.0034 0.2116 0.198
SWR/J m 0.1936 0.0031 0.1998 0.1875


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.1759 0.0023 0.1804 0.1714
A/J both 0.177 0.0023 0.1815 0.1725
BALB/cByJ both 0.1555 0.0022 0.1599 0.1511
C3H/HeJ both 0.147 0.0024 0.1518 0.1423
C57BL/6J both 0.1798 0.0024 0.1846 0.175
FVB/NJ both 0.1869 0.0022 0.1913 0.1825
SWR/J both 0.1992 0.0023 0.2038 0.1946




  GWAS USING LINEAR MIXED MODELS