Project measure / variable:   Schulz1   Cdyn130

ID, description, units MPD:1610   Cdyn130   dynamic compliance of respiratory system with breathing rate of 130 per min (H2O pressure)   [µL/cm]  
Data set, strains Schulz1   inbred   7 strains     sex: both     age: 12-14wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Schulz1 - dynamic compliance of respiratory system with breathing rate of 130 per min (H2O pressure)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means36.7   µL/cm 39.1   µL/cm
Median of the strain means35.3   µL/cm 38.1   µL/cm
SD of the strain means± 3.24 ± 3.69
Coefficient of variation (CV)0.0883 0.0943
Min–max range of strain means33.1   –   41.2   µL/cm 34.9   –   45.5   µL/cm
Mean sample size per strain15.0   mice 15.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 307.219 307.219 13.7349 0.0003
strain 6 1904.3885 317.3981 14.19 < 0.0001
sex:strain 6 273.1854 45.5309 2.0356 0.0627
Residuals 196 4384.0853 22.3678


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 34.7 4.7   15 1.21 0.136 25.5, 44.4 -0.61
129S1/SvImJ m 34.9 3.12   16 0.779 0.0893 27.1, 39.6 -1.14
A/J f 39.1 3.01   16 0.753 0.0771 33.7, 45.4 0.75
A/J m 45.5 3.85   15 0.994 0.0846 38.2, 52.3 1.73
BALB/cByJ f 41.2 3.91   15 1.01 0.0949 36.6, 50.8 1.39
BALB/cByJ m 42.4 3.14   16 0.785 0.0741 34.6, 47.2 0.89
C3H/HeJ f 39.7 5.44   14 1.45 0.137 24.1, 43.4 0.93
C3H/HeJ m 39.3 10.5   15 2.71 0.267 17.5, 54.7 0.05
C57BL/6J f 33.1 3.05   14 0.816 0.0922 27.8, 38.6 -1.11
C57BL/6J m 38.1 2.01   12 0.579 0.0527 34.8, 41.7 -0.28
FVB/NJ f 33.7 3.37   16 0.842 0.0998 29.2, 42.5 -0.92
FVB/NJ m 36.3 5.34   15 1.38 0.147 21.4, 44.1 -0.76
SWR/J f 35.3 5.88   15 1.52 0.166 26.4, 46.4 -0.43
SWR/J m 37.3 2.34   16 0.584 0.0626 31.7, 40.8 -0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 34.6533 1.2211 37.0616 32.2451
129S1/SvImJ m 34.8813 1.1824 37.213 32.5495
A/J f 39.0813 1.1824 41.413 36.7495
A/J m 45.5 1.2211 47.9083 43.0917
BALB/cByJ f 41.1533 1.2211 43.5616 38.7451
BALB/cByJ m 42.3625 1.1824 44.6943 40.0307
C3H/HeJ f 39.7286 1.264 42.2214 37.2358
C3H/HeJ m 39.3 1.2211 41.7083 36.8917
C57BL/6J f 33.1357 1.264 35.6285 30.6429
C57BL/6J m 38.0583 1.3653 40.7509 35.3658
FVB/NJ f 33.7313 1.1824 36.063 31.3995
FVB/NJ m 36.3067 1.2211 38.7149 33.8984
SWR/J f 35.3333 1.2211 37.7416 32.9251
SWR/J m 37.3125 1.1824 39.6443 34.9807


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 34.7673 0.8499 36.4434 33.0912
A/J both 42.2906 0.8499 43.9667 40.6145
BALB/cByJ both 41.7579 0.8499 43.434 40.0818
C3H/HeJ both 39.5143 0.8788 41.2473 37.7812
C57BL/6J both 35.597 0.9303 37.4317 33.7624
FVB/NJ both 35.019 0.8499 36.695 33.3429
SWR/J both 36.3229 0.8499 37.999 34.6468




  GWAS USING LINEAR MIXED MODELS