Project measure / variable:   Schulz1   ratio_Cdyn130_TLC

ID, description, units MPD:1627   ratio_Cdyn130_TLC   dynamic compliance of respiratory system (breathing rate 130/min) related to total lung capacity (H2O pressure)   [1/cm]  
Data set, strains Schulz1   inbred   7 strains     sex: both     age: 12-14wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Schulz1 - dynamic compliance of respiratory system (breathing rate 130/min) related to total lung capacity (H2O pressure)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means0.0292   1/cm 0.0277   1/cm
Median of the strain means0.0285   1/cm 0.0275   1/cm
SD of the strain means± 0.00178 ± 0.00318
Coefficient of variation (CV)0.0609 0.115
Min–max range of strain means0.0269   –   0.0318   1/cm 0.0224   –   0.0324   1/cm
Mean sample size per strain14.6   mice 14.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0001 0.0001 17.6571 < 0.0001
strain 6 0.001 0.0002 23.4606 < 0.0001
sex:strain 6 0.0002 0.0 4.9309 0.0001
Residuals 191 0.0013 0.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0269 0.00278   15 0.000717 0.103 0.0188, 0.0298 -1.32
129S1/SvImJ m 0.0261 0.00166   16 0.000414 0.0633 0.0233, 0.0296 -0.5
A/J f 0.0318 0.00309   16 0.000774 0.0972 0.0259, 0.0375 1.44
A/J m 0.0324 0.00278   14 0.000744 0.0859 0.0263, 0.0386 1.48
BALB/cByJ f 0.0282 0.00198   15 0.000511 0.0702 0.0243, 0.0312 -0.59
BALB/cByJ m 0.0274 0.00241   16 0.000603 0.0879 0.0224, 0.0305 -0.09
C3H/HeJ f 0.0285 0.00284   13 0.000789 0.0998 0.0218, 0.0321 -0.42
C3H/HeJ m 0.0224 0.00398   14 0.00106 0.178 0.0148, 0.0286 -1.67
C57BL/6J f 0.0282 0.00112   14 0.000299 0.0397 0.0266, 0.0302 -0.59
C57BL/6J m 0.0276 0.000946   12 0.000273 0.0343 0.0261, 0.0296 -0.03
FVB/NJ f 0.0299 0.0017   16 0.000425 0.057 0.0274, 0.0331 0.37
FVB/NJ m 0.0275 0.0023   15 0.000593 0.0836 0.0222, 0.0309 -0.06
SWR/J f 0.0312 0.00444   13 0.00123 0.142 0.0243, 0.0386 1.1
SWR/J m 0.0305 0.00237   16 0.000592 0.0776 0.0256, 0.034 0.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0269 0.0007 0.0282 0.0255
129S1/SvImJ m 0.0261 0.0007 0.0274 0.0249
A/J f 0.0318 0.0007 0.0331 0.0305
A/J m 0.0324 0.0007 0.0338 0.031
BALB/cByJ f 0.0282 0.0007 0.0295 0.0268
BALB/cByJ m 0.0274 0.0007 0.0287 0.0262
C3H/HeJ f 0.0285 0.0007 0.0299 0.0271
C3H/HeJ m 0.0223 0.0007 0.0237 0.021
C57BL/6J f 0.0282 0.0007 0.0296 0.0268
C57BL/6J m 0.0276 0.0008 0.0291 0.0261
FVB/NJ f 0.0299 0.0007 0.0311 0.0286
FVB/NJ m 0.0275 0.0007 0.0288 0.0262
SWR/J f 0.0312 0.0007 0.0326 0.0298
SWR/J m 0.0305 0.0007 0.0318 0.0292


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0265 0.0005 0.0274 0.0256
A/J both 0.0321 0.0005 0.0331 0.0312
BALB/cByJ both 0.0278 0.0005 0.0287 0.0269
C3H/HeJ both 0.0254 0.0005 0.0264 0.0244
C57BL/6J both 0.0279 0.0005 0.0289 0.0269
FVB/NJ both 0.0287 0.0005 0.0296 0.0277
SWR/J both 0.0308 0.0005 0.0318 0.0299




  GWAS USING LINEAR MIXED MODELS