Project measure / variable:   GMC12   resp_rate

ID, description, units MPD:56111   resp_rate   respiration rate   [n/min]  
Data set, strains GMC12   inbred w/CC8   8 strains     sex: both     age: 14-15wks
Procedure echocardiography
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC12 - respiration rate



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means249   n/min 270   n/min
Median of the strain means242   n/min 273   n/min
SD of the strain means± 53.7 ± 47.5
Coefficient of variation (CV)0.216 0.176
Min–max range of strain means158   –   331   n/min 192   –   318   n/min
Mean sample size per strain15.0   mice 14.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 19287.0152 19287.0152 1.9493 0.1641
strain 7 564614.9733 80659.2819 8.1521 < 0.0001
sex:strain 7 36059.623 5151.3747 0.5206 0.8185
Residuals 220 2176748.2739 9894.3103


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 224.0 55.9   13 15.5 0.249 110.0, 304.0 -0.46
129S1/SvImJ m 226.0 57.0   14 15.2 0.253 128.0, 338.0 -0.92
A/J f 297.0 57.8   11 17.4 0.195 207.0, 375.0 0.9
A/J m 296.0 79.4   12 22.9 0.268 171.0, 453.0 0.55
C57BL/6J f 218.0 72.5   11 21.8 0.332 76.2, 320.0 -0.58
C57BL/6J m 248.0 67.9   14 18.1 0.273 137.0, 381.0 -0.46
CAST/EiJ f 331.0 170.0   18 40.0 0.513 129.0, 810.0 1.53
CAST/EiJ m 317.0 132.0   14 35.3 0.417 135.0, 702.0 1.0
NOD/ShiLtJ f 280.0 37.0   16 9.24 0.132 220.0, 348.0 0.58
NOD/ShiLtJ m 311.0 49.5   12 14.3 0.159 229.0, 400.0 0.87
NZO/HlLtJ f 251.0 137.0   17 33.3 0.548 154.0, 702.0 0.04
NZO/HlLtJ m 318.0 193.0   17 46.7 0.606 169.0, 709.0 1.02
PWK/PhJ f 158.0 36.1   19 8.29 0.228 94.9, 219.0 -1.69
PWK/PhJ m 192.0 47.9   20 10.7 0.249 141.0, 323.0 -1.64
WSB/EiJ f 232.0 93.1   15 24.0 0.402 32.6, 375.0 -0.31
WSB/EiJ m 250.0 51.6   13 14.3 0.206 174.0, 348.0 -0.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 224.1685 27.5881 278.5392 169.7978
129S1/SvImJ m 225.5014 26.5845 277.8943 173.1085
A/J f 296.7909 29.9914 355.8981 237.6837
A/J m 296.265 28.7146 352.8558 239.6742
C57BL/6J f 217.9464 29.9914 277.0535 158.8392
C57BL/6J m 248.2643 26.5845 300.6572 195.8714
CAST/EiJ f 331.3828 23.4453 377.589 285.1766
CAST/EiJ m 317.2757 26.5845 369.6686 264.8828
NOD/ShiLtJ f 280.25 24.8675 329.2591 231.2409
NOD/ShiLtJ m 311.465 28.7146 368.0558 254.8742
NZO/HlLtJ f 250.6688 24.1251 298.2146 203.123
NZO/HlLtJ m 318.0871 24.1251 365.6329 270.5413
PWK/PhJ f 158.2295 22.82 203.2033 113.2557
PWK/PhJ m 192.247 22.2422 236.0821 148.4119
WSB/EiJ f 231.6193 25.6831 282.2357 181.003
WSB/EiJ m 250.2177 27.5881 304.5884 195.847


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 224.8349 19.1562 262.5881 187.0818
A/J both 296.528 20.7606 337.443 255.6129
C57BL/6J both 233.1053 20.0388 272.598 193.6127
CAST/EiJ both 324.3292 17.723 359.2579 289.4006
NOD/ShiLtJ both 295.8575 18.9929 333.2888 258.4262
NZO/HlLtJ both 284.3779 17.059 317.9979 250.758
PWK/PhJ both 175.2382 15.9332 206.6395 143.837
WSB/EiJ both 240.9185 18.8462 278.0608 203.7763




  GWAS USING LINEAR MIXED MODELS