QTL studies

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Data set Procedure What's in this data set QTL cross Sex Age (weeks) Year
Ackerman1 study archive
with methacholine
Lung, respiratory function, baseline and methacholine-challenged (several doses). airway resistance MCh A/J x C3H/HeJ backcross f 2005
Ankra-Badu1 study archive Body, organ, fat pad weights, weight gain, litter size. subcutaneous, epididymal, liver, kidney, spleen, heart, testis, tail length, L6, M16i None M16i x L6 F2 intercross both 2009
Attie1 study archive eQTL study of obesity and type 2 diabetes using microarray. adipose, gastrocnemius muscle, hypothalamus, pancreatic islets, kidney, liver tissues None B6 x BTBR intercross. both 2015
Bailey1 study archive Open field test. Locomotor activity, anxiety-related behavior. None OFT C57BL/6J and C58/J both 2008
Bautz1 study archive Plasma lipids. Cholesterol, triglycerides. Nsdhl CHOL, TG I/LnJ both 2013
Beamer1 study archive Bone volume. None None C57BL/6J x CAST/EiJ intercross f 1999
Beamer2 study archive Bone morphology and strength, insulin-like growth factor 1. femur, trabecular spacing, peak maximum ultimate break load, stiffness IGF-1, IGF1, INS C57BL/6J x C3H/HeJ intercross F2 progeny f 2001
Bouma1 study archive Fetal gonads microscopy study. Dax1 None Dax1 XY backcross m 2005
Brich1 study archive Protein tau hyperphosphorylation. axonal microtubule stabilizing, Dab1 cytoplasmic adapter None BALB/cByJ x C57BL/6J intercross f 2003
Brockmann1 study archive Body, organ weights, litter size, abdominal fat, lipids, insulin, leptin. Liver, kidney, muscle weights. Cholesterol, triglycerides, insulin-like growth factor, NMRI8, DU6i CHOL, INS, LEP, TG DBA2J x NMRI8 and DBA2J x DU6i intercrosses both 2009
Broman1 study archive Gut length. Sox10, Sox10Dom None C3HeB/FeJ x C57BL/6J intercross both 2006
Bubier2 study archive Intestinal microbiome study. microbiota, flora, gut bacteria None None both 2014
Burke1 study archive Femur and vertebra morphology and strength. Monthly body weight 3 - 13 months. None BW (BALBxB6) F1 x (C3HxDBA/2) F1 f 2012
Chesler6 study archive
with ethanol
Sensitivity to ethanol. Baseline and ethanol. blood alcohol concentration, loss of righting reflex, rotarod, body temperature. EtOH C57BL/6J x 129S1/SvImJ both 2012
Clemens1 study archive
with ultraviolet light
Immunosuppression of contact hypersensitivity after ultraviolet light exposure None UV BALB/cAnNCrl x C57BL/6NCrl backcross both 2000
Davidson1 study archive Exencephaly, neural tube defects in embryos. None None BALB/cJ x FVB/NJ reciprocal backcross both 2007
DiPetrillo3 study archive Blood pressure (tail cuff), heart rate, heart weight. None BP, HR C3H x SWR intercross F2 progeny both 2004
Doorenbos1 study archive Urinalysis. Creatinine, microalbumin, body weight. kidney, Apoe Alb, BW, CREA, MA C57BL/6J_x_A/J_and_A/J_x_B6.Apoe-/-_intercrosses m 2008
Dorward1 study archive Ovarian granulosa cell tumors histopathology. None None CAST/EiJ x SWXJ9/BmJ intercross f 2005
Dzur-Gejdosova1 study archive Sterility investigation. Sperm count, testes weight. None None PWD/Ph and C57BL/6J backcross m 2012
Farmer1 study archive Colitis susceptibility, severity. Colon histopathology, body and spleen weight. cecum, proximal, distal, ulceration, diarrhea, fecal blood, interleukin 10 IL-10, IL-12, IL10, IL12 IL-10-deficient mice both 2001
Feng1 study archive Blood pressure (tail cuff), kidney weight, body weight. None BP, BW 8 mouse intercross populations m 2009
Gatti2 study archive Whole blood neutrophil count and white cell count. None None DO population both 2014
Guay-Woodford1 study archive Kidney morphology, renal cystic disease severity. Bicc1jcpk None BALB/c-Bicc1jcpk-bpk x CAST/EiJ F2 progeny f 2000
Hageman1 study archive eQTL, urinary albumin excretion using microarray. creatinine. Alb, CREA MSxSM F2 intercross m 2011
Ishimori1 study archive
with high-fat diet
Lipids, atherosclerosis lesions, parathyroid hormone after high-fat diet. None BMD, BMI, LW C57BL/6J x 129S1/SvImJ intercross f 2004
Jarvis1 study archive Fat pad weight. Epistatic interactions. None None SM/J x LG/J advanced intercross both 2011
Karst1 study archive Characterization of high-muscle-mass mice. fat, lean, muscle mass, glucose, drip loss, carcass pH, glycogen, lactate, litter size, body weight, coat color, colorimetric assay BW, GLU BMMI816 x BMMI806 (Berlin Muscle Mouse) both 2011
Kiernan1 study archive Ear microscopy (ampullae) and eye slit lamp study. Jag None Jag1 heterozygous mice f 2007
Kim1 study archive Glucose, insulin, body and fat pad weights. None GLU, INS TallyHo and C57BL/6J backcross progeny m 2001
Korstanje3 study archive
with high-fat diet
Cholesterol and phospholipid transfer, baseline vs. high-fat diet. None CHOL, PL SM/J x NZB/BlNJ intercross F2 progeny both 2004
Kumar1 study archive
with cocaine
Open field test. Locomotor, anxiety-related, circadian behavior. Baseline and after cocaine i.p. None OFT C57BL/6J x C57BL/6N reduced complexity cross. both 2014
Leiter2 study archive Type 1 diabetes development study. diabetes score, age of onset, insulitis severity, body weight, bone mineral density, content, muscle, organ weights, glucose, insulin, leptin, fat, lean mass, cholesterol, HDL, fatty acids, triglycerides, colorimetric assay, H2g7, T1D BMD, BW, CHOL, FFA, GLU, INS, LEP, TG NOD x 129.H2g7 backcross. f 2009
Li1 study archive
with western diet
Lipids, atherosclerosis lesion histopathology. High-fat, western-style diet. cholesterol, triglycerides, Apoe CHOL, TG C57BL/6 x C3H intercross f 2008
Lyons1 study archive
with high-fat diet
Lipids (plasma), liver weight, gallbladder and gallstone histopathology. monohydrate crystals, aggregates LW DBA/2J x CAST/EiJ F2 progeny m 2003
Lyons2 study archive
with high-fat diet
Lipids (plasma), bile, liver weight, gallbladder and gallstone histopathology. None LW 129S1/SvImJ x CAST/EiJ F2 progeny m 2003
Lyons3 study archive
with high-fat diet
Lipids, gallbladder and gallstone histopathology after high-fat diet. cholesterol, HDL, triglycerides CHOL, TG 129S1/SvImJ x RIIIS/J F2 intercross m 2004
Lyons4 study archive
with high-fat diet
Gallstone susceptibility. None None NZB/BlNJ x SM/J F2 progeny. both 2005
Maeda1 study archive Atherosclerosis lesion histopathology, lesion sizes. None None None both 2017
Mahler1 study archive Colitis susceptibility. Colon histopathology, spleen weight. cecum, proximal, distal, ulceration, interleukin 10 IL-10, IL10 C3H/HeJBir x C57BL/6J backcrosses both 2002
Mathews1 study archive Type 1 diabetes resistance. T1DM None ALR/Lt x NOD backcross f 2003
Moore1 study archive Gravitropic response in Arabidopsis. arabidopsis, thaliana None Ler x Cvi population both 2013
Mrug1 study archive Kidney morphology. length, weight, volume None cpk mutant mice both 2005
Nishihara1 study archive Blood pressure (tail cuff). systolic, diastolic BP C3H x NZO and NZO x C3H intercross F2 progeny m 2007
Payseur1 study archive Body weight of Gough Island mice. None BW Gough Island mice x WSB intercross. both 2015
Peters5 study archive Complete blood count measures on fetuses, newborns. red cell count, hemoglobin, hematocrit, corpuscular volume, concentration CBC, RBC, WBC, CHCM, HCT, HGB, MCH, MCHC C3H/HeJ+/wan x CAST/EiJ F2 progeny both 2004
Pitman1 study archive
with high-fat diet
Cholesterol (plasma) after high-fat diet (several timepoints). None CHOL NZB/BlNJ x SM/J backcross progeny f 2002
Recla1 study archive Hot plate nociception. None HP DO population both 2013
Reifsnyder1 study archive Body weight (several ages), fat mass, body mass index, fat pad weights. inguinal, peritoneal, mesenteric BMI, BW, GLU, INS, TG NZO/HlLtJ x NON/ShiLtJ backcross m 2000
Reifsnyder2 study archive Type 2 diabetes onset. None None NOD x NOR intercross f 2005
Richards-Smith1 study archive
with macronutrient diet option
Caloric intake, glucose, body and fat pad weights. Macronutrient diet option. retroperitoneal, epididymal, diet choice preference GLU C57BL/6J x CAST/EiJ F2 reciprocal crosses m 2002
Rodriguez1 study archive Spleen, liver murine cytomegalovirus study. natural killer cell-mediated resistance, antiviral responses MCMV NZW x NZB F2 progeny both 2009
Rusyn8 study archive
with trichloroethylene
Trichloroethylene exposure. None None CC  (45) m 2017
Sheehan1 study archive Urinalysis. Creatinine, microalbumin, body weight. None Alb, BW, CREA, MA C57BL/6J x DBA/2J intercross F2 progeny m 2007
Shimomura1 study archive Circadian activity. None None BALB/cJ x C57BL/6J F2 progeny both 2001
Solberg1 study archive Open field test, forced swim test, defensive burying task. None BW, GLU, INS, OFT WKY and Fisher 344 rat strain intercross both 2004
Stylianou1 study archive
with high-fat diet
Body size, weight, fat pad weights after high-fat diet. adiposity index None SM/J x NZB/BlNJ F2 progeny both 2006
Stylianou2 study archive Lipids. Cholesterol, triglycerides, body weight. None BW, CHOL, TG B6.A consomic and F2 mouse crosses both 2006
Su2 study archive
with high-fat diet
Lipids (plasma). Cholesterol, triglycerides, aortic lesions, body mass index. None BMI, CHOL, TG C57BL/6J x C3H/HeJ F2 intercross f 2009
Sugiyama2 study archive
with sodium chloride
Blood pressure (tail cuff) after sodium chloride intake. None BP, NaCl C57BL/6J x A/J reciprocal back crosses m 2001
Sugiyama3 study archive Blood pressure (tail cuff), heart weight, body weight. None BP, BW BALB/cJ and CBA/CaJ F2 progeny m 2002
Sundberg2 study archive Alopecia areata autoimmune disease susceptibility. None None C3H/HeJ x C57BL/6J intercross F2 progeny both 2003
Svenson6 study archive Cholesterol investigation. None CHOL None both 2012
Tsaih1 study archive Brain weight, body weight. None BW inbred intercross (RIX) hybrids both 2005
Wang1 study archive
with high-fat diet
Lipids (plasma). Cholesterol, inducibility, triglycerides, atherosclerosis lesions. None CHOL, TG C57BL/6J and NZB/BlNJ advanced intercross lines f 2003
Wergedal1 study archive Bone mineral density, thickness, strength. peak maximum ultimate break load BMD NZB/BlNJ x RF/J F2 intercross f 2006
Wittenburg1 study archive
with high-fat diet
Liver weight, gallbladder and gallstone histopathology. None LW AKR/J and SWR/J reciprocal backcrosses both 2002
Wittenburg2 study archive
with high-fat diet
Lipids (plasma), liver weight, gallbladder and gallstone histopathology. None LW PERA/EiJ and I/LnJ reciprocal backcrosses both 2003
Wittenburg3 study archive
with high-fat diet
Lipids (plasma), liver weight, gallbladder and gallstone histopathology. None LW DBA/2J and PERA/EiJ intercross both 2005
Xiong1 study archive Circadian behavior. None None C57BL/6J x 129S1/SvImJ backcross m 2011
Yi1 study archive Body weight (several timepoints) and liver weight. M16I BW, LW M16i x CAST backcross both 2007
Yuan5 study archive Plasma levels of P-selectin and soluble vascular cell adhesion molecule-1. Apoe None apoE-/- f 2008
Yuan6 study archive Insulin-like growth factor 1 investigation. None IGF-1, IGF1, INS PLxKK F2 intercross both 2013
Zhang1 study archive
with western diet
Atherosclerosis and glucose homeostasis. Lesions, lipids, glucose, insulin. High-fat, western-style diet. apolipoprotein E-deficient mice, Apoe None C57BL/6 x BALB/cJ intercross f 2012