Doorenbos1: Albuminuria QTL in the presence and absence of Apoe in 2 F2 intercross crosses (2008)

Doorenbos C, Tsaih SW, Sheehan S, Ishimori N, Navis G, Churchill G, Dipetrillo K, Korstanje R. Quantitative trait loci for urinary albumin in crosses between C57BL/6J and A/J inbred mice in the presence and absence of Apoe. Genetics. 2008 May;179(1):693-9.   PubMed 18493081  


       
This project is to identify the genetic loci that control albuminuria in mouse crosses in the presence and abscence of Apoe. For detailed protocols see Doorenbos et al 2008.

Note on studied population: C57BL/6J_x_A/J_and_A/J_x_B6.Apoe-/-_intercrosses

Procedures conducted:
• study archive  Urinalysis. Creatinine, microalbumin, body weight.

Doorenbos1 downloads
QTL projects have several available downloads.
Use the QTL Data Downloads button near the bottom of this page.
Investigators C Doorenbos
Gary A Churchill       The Jackson Laboratory,  Bar Harbor, ME
Participants Tsaih SW, Sheehan S, Ishimori N, Navis G, Dipetrillo K, Korstanje R
ContactGary A Churchill     gary.churchill@jax.org
Affiliated CenterQTL Archive
AcknowledgementsThis work was supported by National Institute of Diabetes and Digestive and Kidney Diseases grant DK-69381 and National Institute of General Medical Sciences grant GM-070683.
Project type QTL Archive data set
MPD identifiersDoorenbos1     MPD:208
Data changelog No updates/corrections.       Initial release date: 10/2009.
QTL data set parameters:
Cross 1: B6 and A/J       Doorenbos1
Progenitor strains A/J     C57BL/6J    
Cross direction notation(B6xA) F1 x (B6xA) F1
Cross typeF2 intercross
Population size 0 ♀     383 ♂
Age8-10wks

Progenitor strains A/J     C57BL/6J.Apoe-/-    
Cross typeNone
Population size None ♀     None ♂
Age8-10wks


Measured phenotypes:       To access these data use the QTL Data Downloads button at bottom of page.
Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
Doorenbos1 urinalysis (none) urinary creatinine   [mg/dL]  UCreat   20801 QTL population m 8-10wks N=383
Doorenbos1 urinalysis (none) microalbumin   [mg/dL]  Microalb   20802 QTL population m 8-10wks N=383
Doorenbos1 urinalysis (none) albumin/creatinine ratio   [mg/g]  Alb/Creat   20803 QTL population m 8-10wks N=383
Doorenbos1 body weight (none) Body Weight   [g]  BW   20804 QTL population m 8-10wks N=383

Associated genomic features
MGI-curated QTL / genomic features that have been associated with this data set:
Albq1   Albq2   Albq3   Albq4  


Cross 1: B6 and A/J     Doorenbos1     a.k.a. Doorenbos_2008a
Excel file:   ._Data_Description_BxA_Doorenbos2008a.xlsx
Excel file:   Data_Description_BxA_Doorenbos2008a.xlsx
CSV file:   Doorenbos2008a_BxA_B37_Data.csv
Readme / text file:   ._readme.txt
Readme / text file:   readme_Doorenbos2008a.txt
QC plots, figures, etc.:   QCReport_Doorenbos2008a.pdf

Project / data set:   Doorenbos1b     a.k.a. None

QTL file list not available on this MPD instance.