Stylianou1: Weight and distribution of fat pads in F2 progeny of SM/J x NZB/BlNJ (2006)

Stylianou IM, Korstanje R, Li R, Sheehan S, Paigen B, Churchill GA. Quantitative trait locus analysis for obesity reveals multiple networks of interacting loci. Mamm Genome. 2006 Jan;17(1):22-36. Epub 2006 Jan 13.   PubMed 16416088  

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Investigators Ioannis M Stylianou       Xenon Pharmaceuticals,  Burnaby, British Columbia CANADA
Gary A Churchill       The Jackson Laboratory,  Bar Harbor, ME
Participants Korstanje R, Li R, Sheehan S, Paigen B
ContactGary A Churchill
Affiliated CenterQTL Archive
AcknowledgementsFunding provided by NIH HL66611, GM070683, CA34196.
Project type QTL Archive data set
MPD identifiersStylianou1     MPD:184
Data changelog No updates/corrections.       Initial release date: 01/2008.
An intercross of 513 F(2) progeny between the SM/J x NZB/BlNJ inbred mouse strains was generated to identify QTLs that are involved in the weight of four fat pads: mesenteric, inguinal, gonadal, and retroperitoneal. Mice were administered a high fat (15%) diet from 8 to 24 wks of age (16 wks on high fat diet). For a detailed protocol see Stylianou et al 2006.

QTL data set parameters:
Progenitor strains NZB/BlNJ     SM/J    
Cross typeF2 intercross
Population size 259 ♀     254 ♂

Measured phenotypes:       To access these data use the QTL Data Downloads button at bottom of page.

Associated genomic features
MGI-curated QTL / genomic features that have been associated with this data set:
Adip10   Adip11   Adip12   Adip13   Adip14   Adip15   Adip16   Adip17   Adip18   Bwtq10   Bwtq11   Bwtq12   Bwtq8   Bwtq9   Obq20   Obq21   Obq22   Obwq1   Obwq2   Obwq3   Obwq4   Obwq5