Karst1: Identification of the genetic determinants for intramuscular fat content and water-holding capacity in high muscle mass mice (2011)

Kärst S, Cheng R, Schmitt AO, Yang H, de Villena FP, Palmer AA, Brockmann GA. Genetic determinants for intramuscular fat content and water-holding capacity in mice selected for high muscle mass. Mamm Genome. 2011 Oct;22(9-10):530-43. Epub 2011 Jul 6.   PubMed 21732194     FullText


     
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Participants B Karst
Abraham A Palmer       University of California, San Diego San Diego, CA
With: Cheng R, Schmitt AO, Yang H, de Villena FP, Brockmann GA
ContactAbraham A Palmer     aapalmer@ucsd.edu
AffiliationChurchill Group QTL Archive
AcknowledgementsThis project was supported by the Deutsche Forschungsgemeinschaft (Project BR1285/8-1) and National Institutes of Health grant R21DA024845.
Project type QTL Archive data set
MPD identifiersKarst1     MPD:260
Data changelog No updates/corrections.       Initial release date: 11/2011.
Intramuscular fat content and water-holding capacity are important traits in livestock. To identify genomic regions affecting them, the progeny of two inbred lines of the Berlin Muscle Mouse (BMMI816 and BMMI806), which have high muscle mass, were used as a QTL research model for livestock. These two strains were crossed reciprocally to generate F1, F2, and G3 intercross populations. Multiple related phenotypes have been measured and this is the data of G3 population. The linkage analyses with G3 animals revealed QTL on chromsome 7 and 2. For detailed protocols, see Karst et al 2011.


QTL data set parameters:
Progenitor strains BMMI806     BMMI816    
Cross direction notation(816 x 806) F2 x (816 x 806) F2; (806 x 816) F2 x (806 x 816) F2
Cross typeG3 reciprocal intercross
Population size 160 ♀     172 ♂
NotesG3 progeny


Measured phenotypes:       To access these data use the QTL Data Downloads button at bottom of page.



Project / data set:   Karst1     a.k.a. Karst_2011
Excel file:   Data_Description_BMMI816x806_Karst2011.xlsx
CSV file:   Karst2011_BMMI816x806_B37_Data.csv
Readme / text file:   readme_Karst2011.txt
QC plots, figures, etc.:   QCReport_Karst2011.pdf