A backcross involving BALB/cAnNCrl and C57BL/6NCrl inbred mouse strains was generated to identify QTLs involved in UV-induced immunosuppression. Backcross progeny were tested for systemic immunosuppression of a contact hypersensitivity response. Intervention: UV radiation dose 4.5 kJ/m
2 for 15 min. Sensitization: trinitrochlorobenzene (TNCB). For detailed protocols see Clemens et al 2000.
Note on studied population: BALB/cAnNCrl x C57BL/6NCrl backcross
Procedures conducted:
• study archive | |
Immunosuppression of contact hypersensitivity after ultraviolet light exposure |