MPD: Phenotype measures mapped to VT:0000184, blood HDL cholesterol amount

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Albers1:2	Albers1	lipid profile	high-fat diet	HDL cholesterol (plasma HDL) [mmol/L] HDLC 1902 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8	1999

Albers1:22	Albers1	lipid profile	high-fat diet	percentage of large HDL particles (10-13 nm) (plasma) [%] largeHDL 1922 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8	1999

Albers1:23	Albers1	lipid profile	high-fat diet	HDL peak size (plasma) [nm] HDLsize 1923 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8	1999

Auwerx1:179	Auwerx1	lipid profile	high-fat diet	blood HDL amount [mmol/L] hdl 111358 CD HFD	BXD w/par	54	m	29wks	N=4	2016

Auwerx2:159	Auwerx2	lipid profile	(none)	plasma HDL amount [mmol/L] hdl 114687 CD HFD	inbred w/CC8	9	both	21wks	N=4	2021

Bautz1:3	Bautz1	lipid profile	(none)	high-density lipoprotein cholesterol, log-transformed [log(mg/dL)] HDL 28003	QTL population		both	12-14wks	N=120	2013

Brockmann1:37	Brockmann1	lipid profile	(none)	HDL cholesterol hdl 21517	QTL population		both	6wks	N=201	2009

CGDpheno1:42	CGDpheno1	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDLD 31842	inbred w/CC8	72	both	12wks	N=7	2009

CGDpheno3:3	CGDpheno3	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL 43903	CC diallel w/par	62	both	8wks	N=5	2012

Eumorphia1:7	Eumorphia1	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL 23907	inbred	4	both	12wks	N=19	2007

GMC06:22	GMC06	lipid profile	(none)	HDL cholesterol (plasma HDL, 16h fast) [mmol/L] HDL 55522	inbred	5	both	10-11wks	N=16	2018

HMDPpheno2:1	HMDPpheno2	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL 46401	HMDP w/par	99	m	16wks	N=7	2010

Ishimori1:3	Ishimori1	lipid profile	high-fat diet	HDL cholesterol (plasma) [mg/dL] HDLC 14003	QTL population		f	20wks	N=294	2004

Ishimori1:4	Ishimori1	lipid profile	high-fat diet	HDL cholesterol (plasma), log transformed [log(mg/dL)] HDLC_log 14004	QTL population		f	20wks	N=294	2004

JaxCC1:9196	JaxCC1	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL 89196	CC	18	both	17-19wks	N=6	2017

JaxCC1:9197	JaxCC1	lipid profile	(none)	HDL cholesterol to total cholesterol ratio [ratio] HDL_total_ratio 89197	CC	18	both	17-19wks	N=6	2017

JaxKOMP-EAP:259	JaxKOMP-EAP	lipid profile	(none)	plasma HDL [mg/dL] hdl_cholesterol hdlx 100688	KOMP	226	both	13wks	N=9	2014

JaxKOMP-EAP:393	JaxKOMP-EAP	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL hdl_cholesterol_hdld 100167 IMPC_CBC_016_001	KOMP	1768	both	17wks	N=6	2021

JaxKOMP-EAP:398	JaxKOMP-EAP	lipid profile	(none)	HDL cholesterol to total cholesterol ratio [ratio] HDL_total_ratio hdld_tchol_ratio 100172	KOMP	1760	both	17wks	N=6	2021

JaxKOMP-LAP:305	JaxKOMP-LAP	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL hdl_cholesterol_hdld 101167 IMPC_CBC_016_001	KOMP	101	both	75-81wks	N=6	2021

JaxKOMP-LAP:310	JaxKOMP-LAP	lipid profile	(none)	HDL cholesterol to total cholesterol ratio [ratio] HDL_total_ratio hdld_tchol_ratio 101172	KOMP	100	both	75-81wks	N=6	2021

Jaxpheno3:35	Jaxpheno3	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL 22835 age 8wks age 16wks	inbred	11	both		N=16	2006

Lake1:26	Lake1	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL 19926	B6.A consomic w/par	23	both	8wks	N=8	2005

Leiter2:19	Leiter2	lipid profile	(none)	HDLD cholesterol in plasma [mg/dL] HDLD 24019	QTL population		f	14-40wks	N=310	2009

Li1:2	Li1	lipid profile	western diet	high-density lipoprotein cholesterol [mm/dL] HDL 21002	QTL population		f	12wks	N=241	2008

Li1:3	Li1	lipid profile	western diet	HDL, log-transformed [log(mm/dL)] LogHDL 21003	QTL population		f	12wks	N=241	2008

Lyons1:11	Lyons1	lipid profile	high-fat diet	HDL (plasma), log transformed [log(mg/dL)] HDL_log 13011	QTL population		m	16-18wks	N=278	2003

Lyons2:11	Lyons2	lipid profile	high-fat diet	HDL cholesterol (plasma) [mg/dL] HDL 13111	QTL population		m	16-18wks	N=277	2003

Lyons3:10	Lyons3	lipid profile	high-fat diet	HDL cholesterol [mg/dL] HDL 14610	QTL population		m	14-20wks	N=330	2004

Paigen1:21	Paigen1	lipid profile	high-fat diet	HDL cholesterol (plasma) [mg/dL] HDL_Ch 2921	inbred	43	both	15-19wks	N=9	2000

Paigen1:23	Paigen1	lipid profile	high-fat diet	percentage of total plasma cholesterol in HDL fraction [%] pctHDL_TCH 2923	inbred	43	both	15-19wks	N=8	2000

Paigen2:4	Paigen2	lipid profile	high-fat diet	HDL cholesterol (plasma) [mg/dL] HDLC 9904 baseline after 17wks on diet Δchange	inbred w/CC7	42	both	7-9wks	N=9	2002

Paigen3:21	Paigen3	lipid profile	high-fat diet	HDL cholesterol (plasma) [mg/dL] HDL_Ch 2821	obesity mutants	8	both	15-19wks	N=18	2000

Paigen3:23	Paigen3	lipid profile	high-fat diet	percentage of total plasma cholesterol in HDL fraction [%] pctHDL_TCH 2823	obesity mutants	8	both	15-19wks	N=16	2000

Paigen4:1	Paigen4	lipid profile	(none)	HDL cholesterol (plasma) [mg/dL] HDLC 19701	inbred w/CC7	43	both	10wks	N=12	2002

Pitman1:1	Pitman1	lipid profile	(none)	HDL cholesterol (plasma), chow [mg/dL] HDL_chow 12301	QTL population		f	6-8wks	N=89	2002

Pitman1:2	Pitman1	lipid profile	high-fat diet	HDL cholesterol (plasma), high-fat diet 4 wks [mg/dL] HDL_fat4 12302	QTL population		f	10-12wks	N=89	2002

Pitman1:3	Pitman1	lipid profile	high-fat diet	HDL cholesterol (plasma), high-fat diet 8 wks [mg/dL] HDL_fat8 12303	QTL population		f	14-16wks	N=89	2002

Pitman1:4	Pitman1	lipid profile	high-fat diet	HDL cholesterol (plasma), high-fat diet 18 wks [mg/dL] HDL_fat18 12304	QTL population		f	24-26wks	N=89	2002

Reifsnyder1:24	Reifsnyder1	lipid profile	(none)	plasma HDL concentration [mg/dL] HDLD 11124	QTL population		m	24wks	N=204	2000

RIKEN-EAD1:24	RIKEN-EAD1	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL 37224	inbred RBRC	37	both	8wks	N=10	2008

RIKEN-EAD2:24	RIKEN-EAD2	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL 37824	wild-derived RBRC	27	both	8wks	N=12	2008

Shockley1:7	Shockley1	lipid profile	high-fat diet	HDL cholesterol (HDL) [mg/dL] HDL 33407 control diet high-fat diet difference	inbred	10	both	10-13wks	N=5	2008

Stylianou2:3	Stylianou2	lipid profile	(none)	HDL cholesterol [mg/dL] HDL 18503	QTL population		both	8-10wks	N=307	2006

Su2:3	Su2	lipid profile	high-fat diet	plasma HDL cholesterol concentration [mg/dL] Week14HDL 24503	QTL population		f	14wks	N=277	2009

Svenson3:65	Svenson3	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL 27365	B6.PWD consomic w/par	28	both	8wks	N=7	2006

Wang1:1	Wang1	lipid profile	(none)	HDL cholesterol (plasma) [mg/dL] HDL_chow 13601	QTL population		f	10wks	N=345	2003

Wang1:2	Wang1	lipid profile	high-fat diet	HDL cholesterol (plasma) [mg/dL] HDL_fat 13602	QTL population		f	10wks	N=345	2003

Wang1:3	Wang1	lipid profile	high-fat diet	HDL inducibility, fold change [fold] HDL_change 13603	QTL population		f	10wks	N=345	2003

Wang1:4	Wang1	lipid profile	high-fat diet	HDL inducibility, percent change [%] HDL_inducibility 13604	QTL population		f	10wks	N=345	2003

Wang1:11	Wang1	lipid profile	(none)	HDL cholesterol (plasma) [mg/dL] HDL_chow_b 13701	QTL population		f	8wks	N=100	2003

Wang1:12	Wang1	lipid profile	high-fat diet	HDL cholesterol (plasma) [mg/dL] HDL_fat4 13702	QTL population		f	12wks	N=100	2003

Wang1:13	Wang1	lipid profile	high-fat diet	HDL inducibility, fold change [fold] HDL_change4 13703	QTL population		f	12wks	N=100	2003

Wang1:14	Wang1	lipid profile	high-fat diet	HDL inducibility, percent change [%] HDL_inducibility4 13704	QTL population		f	12wks	N=100	2003

Wang1:15	Wang1	lipid profile	high-fat diet	HDL cholesterol (plasma) [mg/dL] HDL_fat15 13705	QTL population		f	23wks	N=100	2003

Wang1:16	Wang1	lipid profile	high-fat diet	HDL inducibility, fold change [fold] HDL_change15 13706	QTL population		f	23wks	N=100	2003

Wang1:17	Wang1	lipid profile	high-fat diet	HDL inducibility, percent change [%] HDL_inducibility15 13707	QTL population		f	23wks	N=100	2003

Wang1:24	Wang1	lipid profile	(none)	HDL:nonHDL ratio [ratio] HDL_nonHDL_chow 13714	QTL population		f	8wks	N=100	2003

Wang1:25	Wang1	lipid profile	high-fat diet	HDL:nonHDL ratio [ratio] HDL_nonHDL_fat4 13715	QTL population		f	12wks	N=100	2003

Wang1:26	Wang1	lipid profile	high-fat diet	HDL:nonHDL ratio [ratio] HDL_nonHDL_fat15 13716	QTL population		f	23wks	N=100	2003

Wittenburg2:18	Wittenburg2	lipid profile	high-fat diet	HDL (plasma) [mg/dL] HDL 13818	QTL population		both	14-16wks	N=152	2003

Wittenburg2:19	Wittenburg2	lipid profile	high-fat diet	HDL (plasma), log transformed [log(mg/dL)] HDL_log 13819	QTL population		both	14-16wks	N=152	2003

Wittenburg3:15	Wittenburg3	lipid profile	high-fat diet	HDL cholesterol (plasma) [mg/dL] HDL 18215	QTL population		both	14-16wks	N=162	2005

Wittenburg3:16	Wittenburg3	lipid profile	high-fat diet	HDL cholesterol (plasma), log transformed [log(mg/dL)] HDL_log 18216	QTL population		both	14-16wks	N=162	2005

Yuan3:71	Yuan3	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDL 24471 6mo 12mo 18mo	inbred	32	both		N=7	2008

Zhang1:31	Zhang1	lipid profile	(none)	HDL cholesterol, chow [mg/dL] HDL_Chow 27931	QTL population		f	<6wks	N=266	2012

Zhang1:38	Zhang1	lipid profile	western diet	HDL cholesterol, western diet [mg/dL] HDL_Western 27938	QTL population		f	18wks	N=266	2012

Albers1

lipid profile

high-fat diet

HDL cholesterol (plasma HDL) [mmol/L] HDLC 1902 baseline after 6wks on diet Δchange

inbred

15

both

6-8wks

N=8

1999

Albers1

lipid profile

high-fat diet

percentage of large HDL particles (10-13 nm) (plasma) [%] largeHDL 1922 baseline after 6wks on diet Δchange

inbred

15

both

6-8wks

N=8

1999

Albers1

lipid profile

high-fat diet

HDL peak size (plasma) [nm] HDLsize 1923 baseline after 6wks on diet Δchange

inbred

15

both

6-8wks

N=8

1999

Auwerx1

lipid profile

high-fat diet

blood HDL amount [mmol/L] hdl 111358 CD HFD

BXD w/par

54

m

29wks

N=4

2016

Auwerx2

lipid profile

(none)

plasma HDL amount [mmol/L] hdl 114687 CD HFD

inbred w/CC8

9

both

21wks

N=4

2021

Bautz1

lipid profile

(none)

high-density lipoprotein cholesterol, log-transformed [log(mg/dL)] HDL 28003

QTL population

both

12-14wks

N=120

2013

Brockmann1

lipid profile

(none)

HDL cholesterol hdl 21517

QTL population

both

6wks

N=201

2009

CGDpheno1

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDLD 31842

inbred w/CC8

72

both

12wks

N=7

2009

CGDpheno3

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL 43903

CC diallel w/par

62

both

8wks

N=5

2012

Eumorphia1

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL 23907

inbred

4

both

12wks

N=19

2007

GMC06

lipid profile

(none)

HDL cholesterol (plasma HDL, 16h fast) [mmol/L] HDL 55522

inbred

5

both

10-11wks

N=16

2018

HMDPpheno2

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL 46401

HMDP w/par

99

m

16wks

N=7

2010

Ishimori1

lipid profile

high-fat diet

HDL cholesterol (plasma) [mg/dL] HDLC 14003

QTL population

f

20wks

N=294

2004

Ishimori1

lipid profile

high-fat diet

HDL cholesterol (plasma), log transformed [log(mg/dL)] HDLC_log 14004

QTL population

f

20wks

N=294

2004

JaxCC1

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL 89196

CC

18

both

17-19wks

N=6

2017

JaxCC1

lipid profile

(none)

HDL cholesterol to total cholesterol ratio [ratio] HDL_total_ratio 89197

CC

18

both

17-19wks

N=6

2017

JaxKOMP-EAP

lipid profile

(none)

plasma HDL [mg/dL] hdl_cholesterol hdlx 100688

KOMP

226

both

13wks

N=9

2014

JaxKOMP-EAP

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL hdl_cholesterol_hdld 100167 IMPC_CBC_016_001

KOMP

1768

both

17wks

N=6

2021

JaxKOMP-EAP

lipid profile

(none)

HDL cholesterol to total cholesterol ratio [ratio] HDL_total_ratio hdld_tchol_ratio 100172

KOMP

1760

both

17wks

N=6

2021

JaxKOMP-LAP

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL hdl_cholesterol_hdld 101167 IMPC_CBC_016_001

KOMP

101

both

75-81wks

N=6

2021

JaxKOMP-LAP

lipid profile

(none)

HDL cholesterol to total cholesterol ratio [ratio] HDL_total_ratio hdld_tchol_ratio 101172

KOMP

100

both

75-81wks

N=6

2021

Jaxpheno3

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL 22835 age 8wks age 16wks

inbred

11

both

N=16

2006

Lake1

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL 19926

B6.A consomic w/par

23

both

8wks

N=8

2005

Leiter2

lipid profile

(none)

HDLD cholesterol in plasma [mg/dL] HDLD 24019

QTL population

f

14-40wks

N=310

2009

Li1

lipid profile

western diet

high-density lipoprotein cholesterol [mm/dL] HDL 21002

QTL population

f

12wks

N=241

2008

Li1

lipid profile

western diet

HDL, log-transformed [log(mm/dL)] LogHDL 21003

QTL population

f

12wks

N=241

2008

Lyons1

lipid profile

high-fat diet

HDL (plasma), log transformed [log(mg/dL)] HDL_log 13011

QTL population

m

16-18wks

N=278

2003

Lyons2

lipid profile

high-fat diet

HDL cholesterol (plasma) [mg/dL] HDL 13111

QTL population

m

16-18wks

N=277

2003

Lyons3

lipid profile

high-fat diet

HDL cholesterol [mg/dL] HDL 14610

QTL population

m

14-20wks

N=330

2004

Paigen1

lipid profile

high-fat diet

HDL cholesterol (plasma) [mg/dL] HDL_Ch 2921

inbred

43

both

15-19wks

N=9

2000

Paigen1

lipid profile

high-fat diet

percentage of total plasma cholesterol in HDL fraction [%] pctHDL_TCH 2923

inbred

43

both

15-19wks

N=8

2000

Paigen2

lipid profile

high-fat diet

HDL cholesterol (plasma) [mg/dL] HDLC 9904 baseline after 17wks on diet Δchange

inbred w/CC7

42

both

7-9wks

N=9

2002

Paigen3

lipid profile

high-fat diet

HDL cholesterol (plasma) [mg/dL] HDL_Ch 2821

obesity mutants

8

both

15-19wks

N=18

2000

Paigen3

lipid profile

high-fat diet

percentage of total plasma cholesterol in HDL fraction [%] pctHDL_TCH 2823

obesity mutants

8

both

15-19wks

N=16

2000

Paigen4

lipid profile

(none)

HDL cholesterol (plasma) [mg/dL] HDLC 19701

inbred w/CC7

43

both

10wks

N=12

2002

Pitman1

lipid profile

(none)

HDL cholesterol (plasma), chow [mg/dL] HDL_chow 12301

QTL population

f

6-8wks

N=89

2002

Pitman1

lipid profile

high-fat diet

HDL cholesterol (plasma), high-fat diet 4 wks [mg/dL] HDL_fat4 12302

QTL population

f

10-12wks

N=89

2002

Pitman1

lipid profile

high-fat diet

HDL cholesterol (plasma), high-fat diet 8 wks [mg/dL] HDL_fat8 12303

QTL population

f

14-16wks

N=89

2002

Pitman1

lipid profile

high-fat diet

HDL cholesterol (plasma), high-fat diet 18 wks [mg/dL] HDL_fat18 12304

QTL population

f

24-26wks

N=89

2002

Reifsnyder1

lipid profile

(none)

plasma HDL concentration [mg/dL] HDLD 11124

QTL population

m

24wks

N=204

2000

RIKEN-EAD1

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL 37224

inbred RBRC

37

both

8wks

N=10

2008

RIKEN-EAD2

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL 37824

wild-derived RBRC

27

both

8wks

N=12

2008

Shockley1

lipid profile

high-fat diet

HDL cholesterol (HDL) [mg/dL] HDL 33407 control diet high-fat diet difference

inbred

10

both

10-13wks

N=5

2008

Stylianou2

lipid profile

(none)

HDL cholesterol [mg/dL] HDL 18503

QTL population

both

8-10wks

N=307

2006

Su2

lipid profile

high-fat diet

plasma HDL cholesterol concentration [mg/dL] Week14HDL 24503

QTL population

f

14wks

N=277

2009

Svenson3

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL 27365

B6.PWD consomic w/par

28

both

8wks

N=7

2006

Wang1

lipid profile

(none)

HDL cholesterol (plasma) [mg/dL] HDL_chow 13601

QTL population

f

10wks

N=345

2003

Wang1

lipid profile

high-fat diet

HDL cholesterol (plasma) [mg/dL] HDL_fat 13602

QTL population

f

10wks

N=345

2003

Wang1

lipid profile

high-fat diet

HDL inducibility, fold change [fold] HDL_change 13603

QTL population

f

10wks

N=345

2003

Wang1

lipid profile

high-fat diet

HDL inducibility, percent change [%] HDL_inducibility 13604

QTL population

f

10wks

N=345

2003

Wang1

lipid profile

(none)

HDL cholesterol (plasma) [mg/dL] HDL_chow_b 13701

QTL population

f

8wks

N=100

2003

Wang1

lipid profile

high-fat diet

HDL cholesterol (plasma) [mg/dL] HDL_fat4 13702

QTL population

f

12wks

N=100

2003

Wang1

lipid profile

high-fat diet

HDL inducibility, fold change [fold] HDL_change4 13703

QTL population

f

12wks

N=100

2003

Wang1

lipid profile

high-fat diet

HDL inducibility, percent change [%] HDL_inducibility4 13704

QTL population

f

12wks

N=100

2003

Wang1

lipid profile

high-fat diet

HDL cholesterol (plasma) [mg/dL] HDL_fat15 13705

QTL population

f

23wks

N=100

2003

Wang1

lipid profile

high-fat diet

HDL inducibility, fold change [fold] HDL_change15 13706

QTL population

f

23wks

N=100

2003

Wang1

lipid profile

high-fat diet

HDL inducibility, percent change [%] HDL_inducibility15 13707

QTL population

f

23wks

N=100

2003

Wang1

lipid profile

(none)

HDL:nonHDL ratio [ratio] HDL_nonHDL_chow 13714

QTL population

f

8wks

N=100

2003

Wang1

lipid profile

high-fat diet

HDL:nonHDL ratio [ratio] HDL_nonHDL_fat4 13715

QTL population

f

12wks

N=100

2003

Wang1

lipid profile

high-fat diet

HDL:nonHDL ratio [ratio] HDL_nonHDL_fat15 13716

QTL population

f

23wks

N=100

2003

Wittenburg2

lipid profile

high-fat diet

HDL (plasma) [mg/dL] HDL 13818

QTL population

both

14-16wks

N=152

2003

Wittenburg2

lipid profile

high-fat diet

HDL (plasma), log transformed [log(mg/dL)] HDL_log 13819

QTL population

both

14-16wks

N=152

2003

Wittenburg3

lipid profile

high-fat diet

HDL cholesterol (plasma) [mg/dL] HDL 18215

QTL population

both

14-16wks

N=162

2005

Wittenburg3

lipid profile

high-fat diet

HDL cholesterol (plasma), log transformed [log(mg/dL)] HDL_log 18216

QTL population

both

14-16wks

N=162

2005

Yuan3

lipid profile

(none)

HDL cholesterol (plasma HDL) [mg/dL] HDL 24471 6mo 12mo 18mo

inbred

32

both

N=7

2008

Zhang1

lipid profile

(none)

HDL cholesterol, chow [mg/dL] HDL_Chow 27931

QTL population

f

<6wks

N=266

2012

Zhang1

lipid profile

western diet

HDL cholesterol, western diet [mg/dL] HDL_Western 27938

QTL population

f

18wks

N=266

2012

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