Svenson3: Hematology and blood chemistry of C57BL/6J-Chr#PWD/Ph/ForeJ mouse chromosome substitution strains (2006)

Gregorová S, Divina P, Storchova R, Trachtulec Z, Fotopulosova V, Svenson KL, Donahue LR, Paigen B, Forejt J. Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Res. 2008 Mar;18(3):509-15. Epub 2008 Feb 6.   PubMed 18256238     FullText


           
Notes
Some strain/sexes are N=1 ... these were not accessioned but are present in the "Table format" download file.

Svenson3 downloads
• Download Svenson3 project data set     one row per animal, one column per trait
• Download Svenson3 strain means, SD, N, etc.     one row per strain/sex/measure
Ontology terms mapped to Svenson3 measures:
    MA:0000059   blood
    MA:0002501   plasma
    MP:0000180   abnormal circulating cholesterol level
    MP:0000184   abnormal circulating HDL cholesterol level
    MP:0000188   abnormal circulating glucose level
    MP:0000203   abnormal circulating aspartate transaminase level
    MP:0000217   abnormal leukocyte cell number
    MP:0000226   abnormal mean corpuscular volume
    MP:0000717   abnormal lymphocyte cell number
    MP:0001553   abnormal circulating free fatty acids level
    MP:0001569   abnormal circulating bilirubin level
    MP:0001586   abnormal erythrocyte cell number
    MP:0001588   abnormal hemoglobin
    MP:0001589   abnormal mean corpuscular hemoglobin
    MP:0002586   abnormal platelet volume
    MP:0002596   abnormal hematocrit
    MP:0002602   abnormal eosinophil cell number
    MP:0005265   abnormal blood urea nitrogen level
    MP:0005640   abnormal mean corpuscular hemoglobin concentration
    MP:0008849   abnormal hemoglobin concentration distribution width
    MP:0010066   abnormal red blood cell distribution width
    MP:0010213   abnormal circulating fibrinogen level
    MP:0011898   abnormal platelet cell number
    MP:0011913   abnormal reticulocyte cell number
    MP:0011969   abnormal circulating triglyceride level
    MP:0012324   abnormal circulating antithrombin level
    MP:0012327   abnormal circulating factor VIII level
    MP:0012360   abnormal large unstained cell number
    MP:0012397   abnormal nucleated erythrocyte cell number
    MP:0012440   abnormal neutrophil cell number
    MP:0012441   abnormal monocyte cell number
    MP:0012442   abnormal basophil cell number
    VT:0000180   blood cholesterol amount
    VT:0000184   blood HDL cholesterol amount
    VT:0000188   blood glucose amount
    VT:0000203   blood aspartate transaminase amount
    VT:0000217   leukocyte quantity
    VT:0000222   neutrophil quantity
    VT:0000223   monocyte quantity
    VT:0000248   erythrocyte size trait
    VT:0000717   lymphocyte quantity
    VT:0001553   blood free fatty acid amount
    VT:0001569   blood bilirubin amount
    VT:0001586   erythrocyte quantity
    VT:0001588   blood hemoglobin amount
    VT:0002447   erythrocyte morphology trait
    VT:0002551   blood coagulation trait
    VT:0002602   eosinophil quantity
    VT:0002607   basophil quantity
    VT:0002644   blood triglyceride amount
    VT:0003135   reticulocyte quantity
    VT:0003179   platelet quantity
    VT:0004152   blood iron amount
    VT:0005265   blood urea nitrogen amount
    VT:0010457   platelet size trait
    VT:3000003   fibrin formation trait
Participants Karen L Svenson       The Jackson Laboratory,  Bar Harbor, ME
Jiri Forejt       Academy of Sciences of the Czech Republic,  Prague CZECH REPUBLIC
Leah Rae Donahue       The Jackson Laboratory,  Bar Harbor, ME
Beverly Paigen       The Jackson Laboratory,  Bar Harbor, ME
With: Marion M
ContactKaren L Svenson     karen.svenson@jax.org
AffiliationJAX Heart, Lung, and Blood Center (HLB)
Part of a series: • B6.PWD hematology and blood chemistry   (this project) Svenson3
• B6.PWD body and bone composition   see Svenson4
• B6.PWD sleep patterns   see Svenson5
Project type Phenotype strain survey data set
MPD identifiersSvenson3     MPD:273
Data changelog 1 update/correction.       Initial release date: 07/2012.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Summary of procedures that were conducted
• complete blood count Hematology.
• coagulation test Fibrinogen, anti-thrombin III, factor VIII
• metabolic panel Glucose, bilirubin, blood urea nitrogen, aspartate transaminase (plasma). 4h fast.
• lipid profile Cholesterol, HDL, triglycerides, free fatty acids. 4h fast, plasma.
Mice: B6.PWD consomic w/par   28 strains   ♀♂   age 9wks   1 cohort