Svenson3: Hematology and blood chemistry of C57BL/6J-Chr#PWD/Ph/ForeJ mouse chromosome substitution strains (2006)

Gregorová S, Divina P, Storchova R, Trachtulec Z, Fotopulosova V, Svenson KL, Donahue LR, Paigen B, Forejt J. Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Res. 2008 Mar;18(3):509-15. Epub 2008 Feb 6.   PubMed 18256238     FullText

Some strain/sexes are N=1 ... these were not accessioned but are present in the "Table format" download file.

Svenson3 downloads
• Download Svenson3 project data set     animal data, as uploaded
• Download Svenson3 animal data matrix     with factor-related expansion applied as necessary
• Download Svenson3 strain means, SD, N, etc.     one row per strain/sex/measure
Ontology terms mapped to Svenson3 measures:
  MA:0000059   blood
  MA:0002501   plasma
  MP:0000180   abnormal circulating cholesterol level
  MP:0000184   abnormal circulating HDL cholesterol level
  MP:0000188   abnormal circulating glucose level
  MP:0000203   abnormal circulating aspartate transaminase level
  MP:0000217   abnormal leukocyte cell number
  MP:0000226   abnormal mean corpuscular volume
  MP:0000717   abnormal lymphocyte cell number
  MP:0001553   abnormal circulating free fatty acids level
  MP:0001569   abnormal circulating bilirubin level
  MP:0001586   abnormal erythrocyte cell number
  MP:0001588   abnormal hemoglobin
  MP:0001589   abnormal mean corpuscular hemoglobin
  MP:0002586   abnormal platelet volume
  MP:0002596   abnormal hematocrit
  MP:0002602   abnormal eosinophil cell number
  MP:0005265   abnormal blood urea nitrogen level
  MP:0005640   abnormal mean corpuscular hemoglobin concentration
  MP:0008849   abnormal hemoglobin concentration distribution width
  MP:0010066   abnormal red blood cell distribution width
  MP:0010213   abnormal circulating fibrinogen level
  MP:0011898   abnormal platelet cell number
  MP:0011913   abnormal reticulocyte cell number
  MP:0011969   abnormal circulating triglyceride level
  MP:0012324   abnormal circulating antithrombin level
  MP:0012327   abnormal circulating factor VIII level
  MP:0012360   abnormal large unstained cell number
  MP:0012397   abnormal nucleated erythrocyte cell number
  MP:0012440   abnormal neutrophil cell number
  MP:0012441   abnormal monocyte cell number
  MP:0012442   abnormal basophil cell number
  VT:0000180   blood cholesterol amount
  VT:0000184   blood HDL cholesterol amount
  VT:0000188   blood glucose amount
  VT:0000203   blood aspartate transaminase amount
  VT:0000217   leukocyte quantity
  VT:0000222   neutrophil quantity
  VT:0000223   monocyte quantity
  VT:0000248   erythrocyte size trait
  VT:0000717   lymphocyte quantity
  VT:0001553   blood free fatty acid amount
  VT:0001569   blood bilirubin amount
  VT:0001586   erythrocyte quantity
  VT:0001588   blood hemoglobin amount
  VT:0002447   erythrocyte morphology trait
  VT:0002551   blood coagulation trait
  VT:0002602   eosinophil quantity
  VT:0002607   basophil quantity
  VT:0002644   blood triglyceride amount
  VT:0003135   reticulocyte quantity
  VT:0003179   platelet quantity
  VT:0004152   blood iron amount
  VT:0005265   blood urea nitrogen amount
  VT:0010457   platelet size trait
  VT:3000003   fibrin formation trait

Investigators Karen L Svenson       The Jackson Laboratory,  Bar Harbor, ME
Jiri Forejt       Academy of Sciences of the Czech Republic,  Prague CZECH REPUBLIC
Leah Rae Donahue       The Jackson Laboratory,  Bar Harbor, ME
Beverly Paigen       The Jackson Laboratory,  Bar Harbor, ME
Participants Marion M
ContactKaren L Svenson
Affiliated CenterJAX Heart, Lung, and Blood Center (HLB)
Part of a series: • B6.PWD hematology and blood chemistry   (this project) Svenson3
• B6.PWD body and bone composition   see Svenson4
• None   see Svenson5
Project type Phenotype strain survey data set
MPD identifiersSvenson3     MPD:273
Data changelog 1 update/correction.       Initial release date: 07/2012.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Procedures conducted:
• complete blood count  Hematology.
• coagulation test  Fibrinogen, anti-thrombin III, factor VIII
• metabolic panel  Glucose, bilirubin, blood urea nitrogen, aspartate transaminase (plasma). 4h fast.
• lipid profile  Cholesterol, HDL, triglycerides, free fatty acids. 4h fast, plasma.

Mice: B6.PWD consomic w/par   28 strains   ♀♂   age 9wks   1 experimental group