Phenotype measure

ID, description, units MPD:2823   pctHDL_TCH   percent of total plasma cholesterol in HDL fraction   [%]
high-fat diet study
Data set, strains Paigen3   obesity mutants   8 strains     sex: both     age: 15-19wks
Procedure lipid profile
Ontology mappings


  STRAIN COMPARISON PLOT
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Paigen3 - percent of total plasma cholesterol in HDL fraction



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains8 strains
Mean of the strain means28.6   % 29.4   %
Median of the strain means28.7   % 27.6   %
SD of the strain means± 6.28 ± 8.38
Coefficient of variation (CV)0.219 0.285
Min–max range of strain means19.2   –   37.4   % 20.0   –   41.4   %
Mean sample size per strain17.6   mice 14.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 95.9258 95.9258 0.8028 0.3712
strain 6 9031.1485 1505.1914 12.5962 < 0.0001
sex:strain 6 1671.6263 278.6044 2.3315 0.0333
Residuals 224 26766.9609 119.4954


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.BKS(D)-Leprdb/J m 20.0 4.08   4 2.04 0.204 14.0, 23.1 -1.13
B6.Cg-Ay/J f 32.1 12.4   18 2.91 0.385 15.5, 72.8 0.56
B6.Cg-Ay/J m 31.1 8.27   16 2.07 0.266 20.4, 44.4 0.2
B6.Cg-Lepob/J f 19.2 9.19   16 2.3 0.477 7.55, 33.8 -1.5
B6.Cg-Lepob/J m 20.9 10.5   18 2.47 0.501 5.66, 39.5 -1.02
B6(Cg)-Tubtub/J f 32.6 8.6   21 1.88 0.264 20.0, 49.7 0.63
B6(Cg)-Tubtub/J m 38.3 8.15   20 1.82 0.212 22.3, 49.4 1.06
BKS.Cg-Dock7m +/+ Leprdb/J f 28.2 20.4   18 4.8 0.722 7.19, 73.3 -0.07
BKS.Cg-Dock7m +/+ Leprdb/J m 41.4 20.0   15 5.17 0.484 12.7, 76.2 1.43
BKSChpLt.HRS-Cpefat/J f 22.1 7.78   13 2.16 0.352 10.7, 35.4 -1.04
BKSChpLt.HRS-Cpefat/J m 24.0 8.33   16 2.08 0.347 11.4, 40.0 -0.65
C57BL/6J f 28.7 8.91   13 2.47 0.31 19.1, 51.8 0.01
C57BL/6J m 23.8 4.5   15 1.16 0.189 15.5, 32.5 -0.67
C57BLKS/J f 37.4 6.26   24 1.28 0.167 27.3, 48.8 1.4
C57BLKS/J m 36.1 7.11   15 1.84 0.197 26.1, 48.6 0.79


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.Cg-Ay/J f 32.1056 2.5766 37.1829 27.0282
B6.Cg-Ay/J m 31.0625 2.7328 36.4479 25.6771
B6.Cg-Lepob/J f 19.2406 2.7328 24.626 13.8552
B6.Cg-Lepob/J m 20.9222 2.5766 25.9996 15.8448
B6(Cg)-Tubtub/J f 32.5667 2.3854 37.2674 27.8659
B6(Cg)-Tubtub/J m 38.345 2.4443 43.1618 33.5282
BKS.Cg-Dock7m +/+ Leprdb/J f 28.1828 2.5766 33.2602 23.1054
BKS.Cg-Dock7m +/+ Leprdb/J m 41.3667 2.8225 46.9287 35.8047
BKSChpLt.HRS-Cpefat/J f 22.0769 3.0318 28.0515 16.1024
BKSChpLt.HRS-Cpefat/J m 24.025 2.7328 29.4104 18.6396
C57BL/6J f 28.7 3.0318 34.6745 22.7255
C57BL/6J m 23.7933 2.8225 29.3553 18.2313
C57BLKS/J f 37.3625 2.2314 41.7596 32.9654
C57BLKS/J m 36.08 2.8225 41.642 30.518


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.Cg-Ay/J both 31.584 1.878 35.2848 27.8833
B6.Cg-Lepob/J both 20.0814 1.878 23.7822 16.3807
B6(Cg)-Tubtub/J both 35.4558 1.7077 38.8211 32.0906
BKS.Cg-Dock7m +/+ Leprdb/J both 34.7747 1.9108 38.5402 31.0092
BKSChpLt.HRS-Cpefat/J both 23.051 2.0409 27.0727 19.0292
C57BL/6J both 26.2467 2.0711 30.3281 22.1653
C57BLKS/J both 36.7212 1.799 40.2663 33.1762