Project measure / variable:   GMC06   HDL

ID, description, units MPD:55522   HDL   HDL cholesterol (plasma HDL, 16h fast)   [mmol/L]  
Data set, strains GMC06   inbred   5 strains     sex: both     age: 10-11wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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GMC06 - HDL cholesterol (plasma HDL, 16h fast)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains5 strains
Mean of the strain means2.09   mmol/L 2.53   mmol/L
Median of the strain means1.66   mmol/L 2.15   mmol/L
SD of the strain means± 0.840 ± 0.895
Coefficient of variation (CV)0.402 0.353
Min–max range of strain means1.39   –   3.28   mmol/L 1.62   –   3.86   mmol/L
Mean sample size per strain16.6   mice 16.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7.9561 7.9561 136.5698 < 0.0001
strain 4 97.5759 24.394 418.7306 < 0.0001
sex:strain 4 1.1434 0.2858 4.9065 0.0009
Residuals 153 8.9133 0.0583


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.67 0.154   16 0.0386 0.0577 2.44, 2.96 0.69
129S1/SvImJ m 3.0 0.343   16 0.0857 0.114 2.34, 3.71 0.52
A/J f 1.39 0.0929   16 0.0232 0.0667 1.19, 1.54 -0.84
A/J m 1.62 0.0915   16 0.0229 0.0563 1.45, 1.8 -1.02
C57BL/6J f 1.66 0.0916   16 0.0229 0.0551 1.51, 1.8 -0.51
C57BL/6J m 2.04 0.193   16 0.0482 0.0945 1.48, 2.22 -0.55
NOD/ShiLtJ f 1.46 0.261   18 0.0614 0.178 0.921, 1.8 -0.75
NOD/ShiLtJ m 2.15 0.151   16 0.0377 0.0703 1.86, 2.44 -0.43
NZO/HlLtJ f 3.28 0.218   17 0.0529 0.0665 2.97, 3.95 1.41
NZO/HlLtJ m 3.86 0.49   16 0.122 0.127 2.97, 4.44 1.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.6746 0.0603 2.7938 2.5554
129S1/SvImJ m 3.0049 0.0603 3.1241 2.8857
A/J f 1.392 0.0603 1.5112 1.2728
A/J m 1.6241 0.0603 1.7433 1.5049
C57BL/6J f 1.6635 0.0603 1.7827 1.5443
C57BL/6J m 2.0406 0.0603 2.1598 1.9214
NOD/ShiLtJ f 1.4618 0.0569 1.5742 1.3494
NOD/ShiLtJ m 2.1464 0.0603 2.2656 2.0272
NZO/HlLtJ f 3.2812 0.0585 3.3969 3.1656
NZO/HlLtJ m 3.8621 0.0603 3.9813 3.7429


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.8398 0.0427 2.9241 2.7555
A/J both 1.508 0.0427 1.5923 1.4237
C57BL/6J both 1.852 0.0427 1.9363 1.7677
NOD/ShiLtJ both 1.8041 0.0415 1.886 1.7222
NZO/HlLtJ both 3.5717 0.042 3.6547 3.4886




  GWAS USING LINEAR MIXED MODELS