MPD: Data set: CGDpheno1

Before submitting these data to MPD, the investigators adjusted the strain/sex means using an ANOVA statistical methodology to compensate for differences in seasonal and experimental conditions over 18 months of testing. MPD has accessioned both the adjusted strain means and the unadjusted individual animal values. Views and downloads of strain/sex means will have the ANOVA-adjusted means. Views and downloads of individual animal data points will have unadjusted data.

Because of the above methodology MPD-originating measure modelling analytics will not be available for these measures.

Procedures conducted:

• metabolic panel		Clinical blood chemistry (plasma). 4h fast.
• complete blood count		Hematology.
• lipid profile		Cholesterol, HDL, triglycerides, free fatty acids. 4h fast, plasma.
• DXA		Body mass, fat mass, lean mass, bone mineral density.
• body size and weight		Body weight and length.

CGDpheno1 downloads
• Download CGDpheno1 project data set animal data, as uploaded
• Download CGDpheno1 animal data matrix with factor-related expansion applied as necessary
• Download CGDpheno1 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to CGDpheno1 measures:

Institutional authorship	Center for Genome Dynamics (CGD) Lab web site
Investigators	Ron Korstanje The Jackson Laboratory, Bar Harbor, ME
Participants	Korstanje R, Svenson K, Churchill G, Yang H
Contact	Ron Korstanje ron.korstanje@jax.org Lab web site
Part of a series:	• survey of 72 strains (this project) CGDpheno1 • B6 controls sampled over time see CGDpheno2
Project type	Phenotype strain survey data set
MPD identifiers	CGDpheno1 MPD:318
Data changelog	No updates/corrections. Initial release date: 06/2012.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
CGDpheno1:1	CGDpheno1	complete blood count	(none)	white blood cell count (WBC; per volume x 10³) [n/µL] WBC 31801	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:2	CGDpheno1	complete blood count	(none)	red blood cell count (RBC; per volume x 10⁶) [n/µL] RBC 31802	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:5	CGDpheno1	complete blood count	(none)	neutrophil differential (NEUT; percentage of total WBC) [%] pctNEUT 31805	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:6	CGDpheno1	complete blood count	(none)	lymphocyte differential (LYM; percentage of total WBC) [%] pctLYMP 31806	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:7	CGDpheno1	complete blood count	(none)	monocyte differential (MONO; percentage of total WBC) [%] pctMONO 31807	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:8	CGDpheno1	complete blood count	(none)	eosinophil differential (EOS; percentage of total WBC) [%] pctEOS 31808	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:20	CGDpheno1	complete blood count	(none)	platelet count (PLT; units per volume x 10³) [n/µL] PLT 31820	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:21	CGDpheno1	complete blood count	(none)	mean platelet volume (MPV) [fL] MPV 31821	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:25	CGDpheno1	complete blood count	(none)	hematocrit (HCT) [%] HCT 31825	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:26	CGDpheno1	complete blood count	(none)	measured hemoglobin (HGB) [g/dL] mHGB 31826	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:27	CGDpheno1	complete blood count	(none)	mean RBC corpuscular volume (MCV) [fL] MCV 31827	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:28	CGDpheno1	complete blood count	(none)	mean RBC corpuscular hemoglobin content (MCH) [pg] MCH 31828	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:29	CGDpheno1	complete blood count	(none)	mean RBC corpuscular hemoglobin concentration (MCHC) [g/dL] MCHC 31829	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:31	CGDpheno1	complete blood count	(none)	RBC corpuscular distribution width (RDW) [%] RDW 31831	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:32	CGDpheno1	complete blood count	(none)	hemoglobin concentration distribution width (HDW) [g/dL] HDW 31832	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:34	CGDpheno1	complete blood count	(none)	reticulocyte differential (Retic; percentage of total RBC) [%] pct_Retic 31834	inbred w/CC8	72	both	11wks	N=7

CGDpheno1:41	CGDpheno1	lipid profile	(none)	total cholesterol (plasma CHOL) [mg/dL] CHOL 31841	inbred w/CC8	72	both	12wks	N=7

CGDpheno1:42	CGDpheno1	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] HDLD 31842	inbred w/CC8	72	both	12wks	N=7

CGDpheno1:45	CGDpheno1	lipid profile	(none)	triglycerides (plasma TG, 4h fast) [mg/dL] TG 31845	inbred w/CC8	72	both	12wks	N=7

CGDpheno1:48	CGDpheno1	lipid profile	(none)	non-esterified free fatty acids (plasma NEFA, FFA) [mEq/L] NEFA 31848	inbred w/CC8	72	both	12wks	N=7

CGDpheno1:50	CGDpheno1	metabolic panel	(none)	glucose (plasma GLU, 4h fast) [mg/dL] GLU 31850	inbred w/CC8	72	both	12wks	N=7

CGDpheno1:55	CGDpheno1	metabolic panel	(none)	sodium (plasma Na) [mmol/L] sodium 31855	inbred w/CC8	72	both	12wks	N=8

CGDpheno1:56	CGDpheno1	metabolic panel	(none)	potassium (plasma K) [mmol/L] potassium 31856	inbred w/CC8	72	both	12wks	N=8

CGDpheno1:57	CGDpheno1	metabolic panel	(none)	chloride (plasma Cl) [mmol/L] chloride 31857	inbred w/CC8	72	both	12wks	N=8

CGDpheno1:60	CGDpheno1	metabolic panel	(none)	total bilirubin (plasma TBIL) [µmol/L] TBIL 31860	inbred w/CC8	72	both	12wks	N=7

CGDpheno1:61	CGDpheno1	metabolic panel	(none)	dissolved-ionized carbon dioxide (CO₂) [mmol/L] carbon_dioxide 31861	inbred w/CC8	72	both	12wks	N=8

CGDpheno1:62	CGDpheno1	metabolic panel	(none)	blood urea nitrogen (BUN) [mg/dL] BUN 31862	inbred w/CC8	72	both	12wks	N=7

CGDpheno1:70	CGDpheno1	metabolic panel	(none)	thyroxine (plasma T4) [µg/dL] T4 31870	inbred w/CC8	72	both	12wks	N=7

CGDpheno1:80	CGDpheno1	DXA	(none)	whole body bone mineral density (BMD) [g/cm²] BMD 31880	inbred w/CC7	71	both	13wks	N=7

CGDpheno1:84	CGDpheno1	DXA	(none)	total tissue mass, head excluded [g] TTM 31884	inbred w/CC7	71	both	13wks	N=7

CGDpheno1:85	CGDpheno1	DXA	(none)	lean tissue mass, head excluded [g] LTM 31885	inbred w/CC7	71	both	13wks	N=7

CGDpheno1:87	CGDpheno1	DXA	(none)	percent fat, head excluded [%] pctFat 31887	inbred w/CC7	71	both	13wks	N=7

CGDpheno1:88	CGDpheno1	body size and weight	(none)	body weight [g] bodyweight 31888	inbred w/CC7	71	both	13wks	N=7

CGDpheno1:89	CGDpheno1	body size and weight	(none)	body length (tip of nose to base of tail) [cm] bodylength 31889	inbred w/CC7	71	both	13wks	N=7

CGDpheno1: Multi-system survey of mouse physiology in 72 inbred strains of mice (ANOVA-adjusted methodology) (2009)

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