CGDpheno1: Multi-system survey of mouse physiology in 72 inbred strains of mice (ANOVA-adjusted methodology) (2009)

Center for Genome Dynamics (CGD)   Ron Korstanje   With: Korstanje R, Svenson K, Churchill G, Yang H

CGDpheno1 downloads
• Download CGDpheno1 project data set     animal data, as uploaded
• Download CGDpheno1 animal data matrix     with factor-related expansion applied as necessary
• Download CGDpheno1 strain means, SD, N, etc.     one row per strain/sex/measure
Ontology terms mapped to CGDpheno1 measures:
  MA:0000009   adipose tissue
  MA:0000059   blood
  MA:0001459   bone
  MA:0002501   plasma
  MP:0000180   abnormal circulating cholesterol level
  MP:0000184   abnormal circulating HDL cholesterol level
  MP:0000188   abnormal circulating glucose level
  MP:0000217   abnormal leukocyte cell number
  MP:0000226   abnormal mean corpuscular volume
  MP:0000717   abnormal lymphocyte cell number
  MP:0001256   abnormal body length
  MP:0001259   abnormal body weight
  MP:0001553   abnormal circulating free fatty acids level
  MP:0001569   abnormal circulating bilirubin level
  MP:0001586   abnormal erythrocyte cell number
  MP:0001588   abnormal hemoglobin
  MP:0001589   abnormal mean corpuscular hemoglobin
  MP:0001776   abnormal circulating sodium level
  MP:0002089   abnormal postnatal growth/weight/body size
  MP:0002586   abnormal platelet volume
  MP:0002596   abnormal hematocrit
  MP:0002602   abnormal eosinophil cell number
  MP:0002668   abnormal circulating potassium level
  MP:0003018   abnormal circulating chloride level
  MP:0003860   abnormal carbon dioxide level
  MP:0003959   abnormal lean body mass
  MP:0005265   abnormal blood urea nitrogen level
  MP:0005457   abnormal percent body fat/body weight
  MP:0005475   abnormal circulating thyroxine level
  MP:0005640   abnormal mean corpuscular hemoglobin concentration
  MP:0008849   abnormal hemoglobin concentration distribution width
  MP:0010066   abnormal red blood cell distribution width
  MP:0010119   abnormal bone mineral density
  MP:0011898   abnormal platelet cell number
  MP:0011913   abnormal reticulocyte cell number
  MP:0011969   abnormal circulating triglyceride level
  MP:0012321   abnormal total tissue mass
  MP:0012397   abnormal nucleated erythrocyte cell number
  MP:0012440   abnormal neutrophil cell number
  MP:0012441   abnormal monocyte cell number
  VT:0000180   blood cholesterol amount
  VT:0000184   blood HDL cholesterol amount
  VT:0000188   blood glucose amount
  VT:0000217   leukocyte quantity
  VT:0000222   neutrophil quantity
  VT:0000223   monocyte quantity
  VT:0000248   erythrocyte size trait
  VT:0000717   lymphocyte quantity
  VT:0001256   body length
  VT:0001259   body mass
  VT:0001553   blood free fatty acid amount
  VT:0001569   blood bilirubin amount
  VT:0001586   erythrocyte quantity
  VT:0001588   blood hemoglobin amount
  VT:0001776   blood sodium amount
  VT:0002329   blood gas amount
  VT:0002447   erythrocyte morphology trait
  VT:0002602   eosinophil quantity
  VT:0002644   blood triglyceride amount
  VT:0002668   blood potassium amount
  VT:0003018   blood chloride amount
  VT:0003135   reticulocyte quantity
  VT:0003179   platelet quantity
  VT:0004152   blood iron amount
  VT:0005007   bone mineral mass
  VT:0005265   blood urea nitrogen amount
  VT:0005452   adipose amount
  VT:0005475   blood thyroxine amount
  VT:0010457   platelet size trait
  VT:0010482   body fat mass
  VT:0010483   body lean mass

Institutional authorship Center for Genome Dynamics (CGD)     Lab web site
Investigators Ron Korstanje       The Jackson Laboratory,  Bar Harbor, ME
Participants Korstanje R, Svenson K, Churchill G, Yang H
ContactRon Korstanje     Lab web site
Part of a series: • survey of 72 strains   (this project) CGDpheno1
• B6 controls sampled over time   see CGDpheno2
Project type Phenotype strain survey data set
MPD identifiersCGDpheno1     MPD:318
Data changelog No updates/corrections.       Initial release date: 06/2012.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Before submitting these data to MPD, the investigators adjusted the strain/sex means using an ANOVA statistical methodology to compensate for differences in seasonal and experimental conditions over 18 months of testing. MPD has accessioned both the adjusted strain means and the unadjusted individual animal values. Views and downloads of strain/sex means will have the ANOVA-adjusted means. Views and downloads of individual animal data points will have unadjusted data.

Because of the above methodology MPD-originating measure modelling analytics will not be available for these measures.

Procedures conducted:
• metabolic panel  Clinical blood chemistry (plasma). 4h fast.
• complete blood count  Hematology.
• lipid profile  Cholesterol, HDL, triglycerides, free fatty acids. 4h fast, plasma.
• DXA  Body mass, fat mass, lean mass, bone mineral density.
• body size and weight  Body weight and length.

Mice: inbred w/CC8   72 strains   ♀♂   age 10-13wks   1 experimental group