CGDpheno1: Multi-system survey of mouse physiology in 72 inbred strains of mice (ANOVA-adjusted methodology) (2009)

Center for Genome Dynamics (CGD)   With: Korstanje R, Svenson K, Churchill G, Yang H

       
CGDpheno1 downloads
• Download CGDpheno1 project data set     one row per animal, one column per trait
• Download CGDpheno1 strain means, SD, N, etc.     one row per strain/sex/measure
Institutional authorship Center for Genome Dynamics (CGD)     Lab web site
Participants Korstanje R, Svenson K, Churchill G, Yang H
ContactRon Korstanje     ron.korstanje@jax.org     Lab web site
AffiliationCenter for Genome Dynamics (CGD)
Part of a series: • survey of 72 strains   (this project) CGDpheno1
• B6 controls sampled over time   see CGDpheno2
Project type Phenotype strain survey data set
MPD identifiersCGDpheno1     MPD:318
Data changelog No updates/corrections.       Initial release date: 06/2012.
Formatted citation
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The investigators adjusted the strain/sex means using an ANOVA statistical methodology to compensate for differences in seasonal and experimental conditions over 18 months of testing. MPD has accessioned both the adjusted strain means and the unadjusted individual animal values. Views and downloads of strain/sex means will have the ANOVA-adjusted means. Views and downloads of individual animal data points will have unadjusted data.

Summary of procedures that were conducted
• metabolic panel Clinical blood chemistry (plasma). 4h fast.
• complete blood count Hematology.
• lipid profile Cholesterol, HDL, triglycerides, free fatty acids. 4h fast, plasma.
• DXA Body mass, fat mass, lean mass, bone mineral density.
• body size and weight Body weight and length.
Mice: inbred   72 strains   ♀♂   age 10-13wks   1 cohort

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    CGDpheno1 31801 complete blood count (none) white blood cell count (WBC; per volume x 103)   [n/µL]  WBC inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31802 complete blood count (none) red blood cell count (RBC; per volume x 106)   [n/µL]  RBC inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31805 complete blood count (none) neutrophil differential (percent of total WBC)   [%]  pctNEUT inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31806 complete blood count (none) lymphocyte differential (percent of total WBC)   [%]  pctLYMP inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31807 complete blood count (none) monocyte differential (percent of total WBC)   [%]  pctMONO inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31808 complete blood count (none) eosinophil differential (percent of total WBC)   [%]  pctEOS inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31820 complete blood count (none) platelet count (PLT; units per volume x 103)   [n/µL]  PLT inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31821 complete blood count (none) mean platelet volume (MPV)   [fL]  MPV inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31825 complete blood count (none) hematocrit (HCT)   [%]  HCT inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31826 complete blood count (none) measured hemoglobin (HGB)   [g/dL]  mHGB inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31827 complete blood count (none) mean RBC corpuscular volume (MCV)   [fL]  MCV inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31828 complete blood count (none) mean RBC corpuscular hemoglobin content (MCH)   [pg]  MCH inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31829 complete blood count (none) mean RBC corpuscular hemoglobin concentration (MCHC)   [g/dL]  MCHC inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31831 complete blood count (none) RBC corpuscular distribution width (RDW)   [%]  RDW inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31832 complete blood count (none) hemoglobin concentration distribution width (HDW)   [g/dL]  HDW inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31834 complete blood count (none) reticulocyte differential (percent of total RBC)   [%]  pct_Retic inbred w/CC8 72 both 11wks N=7
    CGDpheno1 31841 lipid profile (none) total cholesterol (plasma CHOL)   [mg/dL]  CHOL inbred w/CC8 72 both 12wks N=7
    CGDpheno1 31842 lipid profile (none) HDL cholesterol (plasma HDL)   [mg/dL]  HDLD inbred w/CC8 72 both 12wks N=7
    CGDpheno1 31845 lipid profile (none) triglycerides (plasma TG, 4h fast)   [mg/dL]  TG inbred w/CC8 72 both 12wks N=7
    CGDpheno1 31848 lipid profile (none) non-esterified free fatty acids (plasma NEFA, FFA)   [mEq/L]  NEFA inbred w/CC8 72 both 12wks N=7
    CGDpheno1 31850 metabolic panel (none) glucose (plasma GLU, 4h fast)   [mg/dL]  GLU inbred w/CC8 72 both 12wks N=7
    CGDpheno1 31855 metabolic panel (none) sodium (plasma Na)   [mmol/L]  sodium inbred w/CC8 72 both 10wks N=8
    CGDpheno1 31856 metabolic panel (none) potassium (plasma K)   [mmol/L]  potassium inbred w/CC8 72 both 10wks N=8
    CGDpheno1 31857 metabolic panel (none) chloride (plasma Cl)   [mmol/L]  chloride inbred w/CC8 72 both 10wks N=8
    CGDpheno1 31860 metabolic panel (none) total bilirubin (plasma TBIL)   [µmol/L]  TBIL inbred w/CC8 72 both 12wks N=7
    CGDpheno1 31861 metabolic panel (none) dissolved-ionized carbon dioxide (CO2)   [mmol/L]  carbon_dioxide inbred w/CC8 72 both 10wks N=8
    CGDpheno1 31862 metabolic panel (none) blood urea nitrogen (BUN)   [mg/dL]  BUN inbred w/CC8 71 both 12wks N=7
    CGDpheno1 31870 metabolic panel (none) thyroxine (plasma T4)   [µg/dL]  T4 inbred w/CC8 72 both 12wks N=7
    CGDpheno1 31880 DXA (none) whole body bone mineral density (BMD)   [g/cm2]  BMD inbred w/CC7 69 both 13wks N=7
    CGDpheno1 31884 DXA (none) total tissue mass, head excluded   [g]  TTM inbred w/CC7 69 both 13wks N=7
    CGDpheno1 31885 DXA (none) lean tissue mass, head excluded   [g]  LTM inbred w/CC7 69 both 13wks N=7
    CGDpheno1 31887 DXA (none) percent fat, head excluded   [%]  pctFat inbred w/CC7 69 both 13wks N=7
    CGDpheno1 31888 body size and weight (none) body weight   [g]  bodyweight inbred w/CC7 69 both 13wks N=7
    CGDpheno1 31889 body size and weight (none) body length (tip of nose to base of tail)   [cm]  bodylength inbred w/CC7 66 both 13wks N=7
    All boxes             To see more rows use the paging control at top.