Project measure / variable:   Eumorphia1   HDL

ID, description, units MPD:23907   HDL   HDL cholesterol (plasma HDL)   [mg/dL]  
Data set, strains Eumorphia1   inbred   4 strains     sex: both     age: 12wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Eumorphia1 - HDL cholesterol (plasma HDL)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means70.4   mg/dL 88.1   mg/dL
Median of the strain means69.4   mg/dL 88.3   mg/dL
SD of the strain means± 6.27 ± 9.63
Coefficient of variation (CV)0.0891 0.109
Min–max range of strain means63.9   –   78.9   mg/dL 76.8   –   98.8   mg/dL
Mean sample size per strain18.8   mice 18.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 11723.1159 11723.1159 94.9926 < 0.0001
strain 3 4106.0569 1368.6856 11.0905 < 0.0001
sex:strain 3 3437.2732 1145.7577 9.2841 < 0.0001
Residuals 141 17400.9216 123.4108


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 78.9 8.72   20 1.95 0.111 54.2, 94.0 1.35
129S2/SvPas m 84.1 11.4   18 2.68 0.135 50.3, 102.0 -0.41
BALB/cJ f 70.3 9.19   18 2.17 0.131 54.2, 80.3 -0.02
BALB/cJ m 92.6 15.9   18 3.76 0.172 69.4, 120.0 0.47
C3HeB/FeJ f 68.5 5.47   19 1.26 0.0799 60.8, 79.2 -0.3
C3HeB/FeJ m 98.8 5.95   20 1.33 0.0602 88.1, 110.0 1.11
C57BL/6J f 63.9 15.1   18 3.56 0.236 34.3, 88.9 -1.04
C57BL/6J m 76.8 13.1   18 3.09 0.171 53.4, 91.3 -1.17


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 78.88 2.4841 83.7908 73.9692
129S2/SvPas m 84.05 2.6184 89.2264 78.8736
BALB/cJ f 70.3389 2.6184 75.5153 65.1624
BALB/cJ m 92.5556 2.6184 97.732 87.3791
C3HeB/FeJ f 68.5105 2.5486 73.5489 63.4721
C3HeB/FeJ m 98.85 2.4841 103.7608 93.9392
C57BL/6J f 63.8833 2.6184 69.0598 58.7069
C57BL/6J m 76.7556 2.6184 81.932 71.5791


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 81.465 1.8046 85.0326 77.8974
BALB/cJ both 81.4472 1.8515 85.1075 77.7869
C3HeB/FeJ both 83.6803 1.7795 87.1981 80.1624
C57BL/6J both 70.3194 1.8515 73.9797 66.6591




GWAS analysis not available: SNP data is not available for enough strains (at least 4)