MPD: Data set: Albers1

Albers JJ, Pitman W, Wolfbauer G, Cheung MC, Kennedy H, Tu AY, Marcovina SM, Paigen B. Relationship between phospholipid transfer protein activity and HDL level and size among inbred mouse strains. J Lipid Res. 1999 Feb;40(2):295-301. PubMed 9925659

Albers1 downloads
• Download Albers1 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Albers1 measures:

MA:0002501 plasma
MP:0000180 abnormal circulating cholesterol level
MP:0000184 abnormal circulating HDL cholesterol level
MP:0006084 abnormal circulating phospholipid level
MP:0011969 abnormal circulating triglyceride level
MP:0012780 abnormal phospholipid transfer protein activity
MP:0020124 abnormal circulating HDL phospholipid level
MP:0020127 abnormal circulating non-HDL phospholipid level
MP:0020151 abnormal circulating non-HDL cholesterol level
VT:0000180 blood cholesterol amount
VT:0000184 blood HDL cholesterol amount
VT:0002644 blood triglyceride amount
VT:0006084 blood phospholipid amount
VT:0010474 blood non-HDL cholesterol amount

Investigators	John J Albers University of Washington, Seattle, WA Beverly Paigen The Jackson Laboratory, Bar Harbor, ME
Participants	Pitman W, Wolfbauer G, Cheung MC Kennedy H, Tu AY, Marcovina SM
Contact	John J Albers jja@u.washington.edu
Acknowledgements	Funding provided by NIH HL30086, HL32087, HL49546, DK02456
Project type	Phenotype strain survey data set
MPD identifiers	Albers1 MPD:19
Data changelog	No updates/corrections. Initial release date: 05/2003.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Plasma phospholipid transfer protein activity and lipoprotein phospholipid parameters were characterized at baseline and then again after 6 wks on high fat diet.

Procedures conducted:

• lipid profile		Cholesterol, HDL, non-HDL, triglycerides, phospholipids. 4h fast, plasma. Baseline vs. high-fat diet (6wks).
• protein activity assessment		Phospholipid transfer protein activity. 4h fast.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Albers1:1	Albers1	lipid profile	high-fat diet	total cholesterol (plasma CHOL) [mmol/L] chol 1901 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8

Albers1:2	Albers1	lipid profile	high-fat diet	HDL cholesterol (plasma HDL) [mmol/L] HDLC 1902 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8

Albers1:3	Albers1	lipid profile	high-fat diet	non-HDL cholesterol (plasma non-HDL) [mmol/L] nonHDLC 1903 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8

Albers1:10	Albers1	lipid profile	high-fat diet	total phospholipid (plasma) [mmol/L] PL 1910 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8

Albers1:11	Albers1	lipid profile	high-fat diet	HDL phospholipid (plasma) [mmol/L] PL_HDL 1911 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8

Albers1:12	Albers1	lipid profile	high-fat diet	non-HDL phospholipid (plasma) [mmol/L] PL_nonHDL 1912 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8

Albers1:13	Albers1	protein activity assessment	high-fat diet	phospholipid transfer protein activity (plasma) [µmol/mL/h] PLTP 1913 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8

Albers1:22	Albers1	lipid profile	high-fat diet	percentage of large HDL particles (10-13 nm) (plasma) [%] largeHDL 1922 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8

Albers1:23	Albers1	lipid profile	high-fat diet	HDL peak size (plasma) [nm] HDLsize 1923 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8

Albers1:28	Albers1	lipid profile	high-fat diet	triglycerides (plasma TG) (4h fast) [mmol/L] TG 1928 baseline after 6wks on diet Δchange	inbred	15	both	6-8wks	N=8

Albers1: Diet-induced changes in plasma phospholipid transfer protein activity, lipids, and lipoproteins in 15 inbred strains of mice (1999)